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11 Cards in this Set

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Types of Combination Inhalers

Advair


Symbicort

Types of oral corticosteroids

Prednisone


Prednisolone


Methylprednisolone

Anti-Leukotrienes

Block the action of leukotrienes, which cause inflammation and mucus secretion associated with allergies, thus preventing bronchial constriction.


E.g: Montelukast sodium (Singulair)

To reduce some types of airway allergic reactions - NOT for immediate relief

Beta-2 Agonist Bronchodilators

Used for rapid symptom relief.



Ventolin (Salbutamol)

Anti-cholinergic bronchodilators

Promotes smooth muscle relaxation of the bronchi by binding to muscarinic receptors.


E.g.: Iptrotropium bromide (atrovent)


- Peak effect 30-45 min; lasts 6-8 hours


Tiotropium bromide (Flovent)


- 24-hr duration; sustained improvements in lung function and reduce frequency of exacerbations

Names of inhaled corticosteroids

Beclomethasone (Beclovent)


Fluticasone (Flovent)

Symptoms of COPD

- chronic / persistent cough


- increased sputum production


- dyspnea


- wheezing


- chest tightness

Medications for COPD management

LABAs, or


Combination ICS and LABAs

Medications for COPD exacerbation

- antibiotics


- oral corticosteroids

How can COPD lead to pulmonary hypertension?

Inflammatory changes lead to excessive mucus production, leading to:


1. Chronic obstruction (decreased O2 and increased CO2)


2. Alveolar hypoxia —> RHF and decreased LV output —> fluid retention —> ‘blue bloaters’

Treatment of COPD exacerbations

1. Supplemental O2


2. Inhaled beta-agonist (SABA)


3. Oral corticosteroids


4. Broad-spectrum antibiotics


- Cipro, Amoxicillin, Doxycycline


- +/- Macrolide (Azithro, clarithromycin)