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17 Cards in this Set
- Front
- Back
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hallmarks of AHC dz |
-pure weakness, sensory OK -LMN (ALS is the only one with also UMN) -fasciculations |
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UMN lesions in ALS |
corticospinal & corticobulbar tracts |
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pseudobulbar palsy: degen of corticobulbar tract |
emotional lability, dysarthria, dysphagia |
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LMN in ALS |
AHC & brainstem degen (primarily motor nuclei in medulla) |
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motor nuclei: nucleus ambiguous & hypoglossal nucleus |
dysarthria/dysphagia (BULBAR PALSY) |
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low amplitude CMAP, but NORMAL SNAP |
ALS |
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fasciculations/fibrillations & large motor unitis |
ALS |
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how are bowel & bladder in ALS? |
preserved |
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why is it that eye movements are ok until very late in ALS? |
higher brain stem motor units are preserved |
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where are the anterior horn cells? |
skinny part of butterfly (fat part is preserved-sensory) |
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what happens if you have EXCESSIVE GLUTAMATE which overstimulates NMDAreceptors--->causing overload of Ca++ in the post synaptic neuron? |
cell death: damanage/death after stroke, seizures, ALS |
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reflexes in ALS |
up and down |
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reflexes in peripheral neuropathy |
decreased |
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reflexes in MG & myopathy |
normal |
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spastic & flaccid weakness |
ALS |
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distal/flaccid weakness |
PN |
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Dx of West Nile |
WNV-specific IgG and IgM antibodies |
