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51 Cards in this Set

  • Front
  • Back

Prevention Bacterial Meningitis

Health education


Immunization: Bi, Tri, Quadrivalant


not result in Herd Immunitu



Control of Bacterial Meningitis

Report to LHO


Isolation


Concurrent disinfection


Protection of contacts- Rifampicin -


Investigation of contacts


Specifc Treatment



Drug: Does NOT cause Prolactinemia:

Resperpine

Drug: Treatment of Opoid dependency

Methadone

Buprenorphine:

Partial Agonist at u Receptor

Tolerance occurs to all of Actions of Opoids EXCEPT

Miosis

New born develops respiratory depression in postoperative wards: result of?

opoids

Naltrexone used in treatment of _____ of Opoid addiction

Overdose


NOT an Opoid Agonist

Ketamine


Pregnant tonic clonic seizures uses Phenobaritone stops 4 month into pregnancy:

Decision wrong for risk of Teratogenacity toxicity is highest at first trimester

Fetal Hydantoin Syndrome seen in pregnancy +

Phenytoin

Effect of Valproate EXCEPT

Osteomalacia

Enhances levels of Levodopa in Parkinson's

Entacapone

History of Head injury , NOT to use for analgesia

morphine

Chronic treatment of Epelipsy , S/E hirtruism & gingval Hyperplasia

Phenytoin

Entacapone useful in Levodopa-carbidopa treatment b/c

Decreases formation of 3-OMD

Antiepeliptic drug used for treatment of Post herpetic neuralgia

Gaba pentin

Tramadol

opoid analgesc

Abcensce seizure

Ethosuxamide

Headache Aspirin => severe shortness of breathe


Responsible?

Leukotriends

Action of Aspirin at lowest dose

Antiplatelet

Acute inflammatory swelling of lower limb:


NOT useful ?

Paracetamol

Post-operative pain, NSAIDS:

Ketoralic

Child +Viral infection + high fever


C/I NSAIDS?

Aspirin

Parkinsonism: Levodopa + vit b =>

Decreased Efficacy

Selegilline: NOT

a MOA-A inhibitor

Granulomatous amebic meningo-encephalitis (GAM) is caused by:

Acanthamoeba Castellani

Protozoan + Nuclear Chromatin particles

Entamoeba histolytica

Trypsonomiasis Lab Diagnosis?

Aspirate Chancre


Csf Examination

NOT a pathogenic free living amoeba

Entamoeba Histolytica

Plasmodium Falciparum does NOT

produces single infection of the RBCs.

A woman + returned from Africa+paroxysmal attacks of chills, fever, and sweating


last a day or two at a time and recur every 36 to 48 h.


Examination of a stained blood : ring like and crescent-like forms within red blood cells.

Plasmodium falciparum

Protozoan flagellated

N. fowleri

Primary amoebic meningo-encephalitis (PAM)

N.fowleri


Spine like psuedopods trophozoite

Acanthamoeba castellani

Polymorphic pattern of Trypomastigote

Trypanosoma gambiense

WRONG : neiseria meningitis:

coagulase production

All of the Meningococci ,pneumococci has

Capsule


Case: Brain abscess after teeth removal:

Aneurobic streptococci

Neiseria meningitis :

Produce enzymes: igA oxidase, oxidase


CAN"T Exotoxin

Case: young boy +missed immunzation + Meningitis+ CSF ^^ polymorphs & Gram stain -ve poliomorphic rods, Isolation on chocolate agar

H. influenza


VF: Polysacchride capsule

Newborn + meningitis+ short gram +ve rods

Neisseria onocytoges (form mother birth canal, unpasterized milk)


(Lesteria monocytogenes?)

H.influenza confirm

chocolate agar x and v factor

Neonatal meningitis + bulging of ant frotal +gp B stretoticocci: Patho?

capsule invade csf , dont have anticapsular 'specif" Ab,-> negative opsonization " enhance Phagocytosis"

Lesteria monocytogenes infect young child with all vaccines for septic meningitis

No vacc for lesteria, e.coli, strepto A & B

Child died of septic shock , gram -ve isolated in blodd & csf


fever, hypotenstion

"meningococci"


Cultre?; Modified thayer martin medium


imp VF: Endotoxin : lipooligosacchride

Rabies virus

Causes late manifestation: previleged site: away from immunity


ACTIVE PASSIVE and Active vacc

Child bitten dog with Rabies: Delayed immunity?

replicate at privileged site

N.meningitis:

facultativea anaerobe


has oxidase enzyme

Immunocompromised +/ temporal lobe lesion + Multinucleated giant cell (intranucleus)

Inclusion bodies, herpis simplex virus

Meningitis seen with

C5-C9 deffincency "genetics"