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29 Cards in this Set
- Front
- Back
- 3rd side (hint)
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predominately natural killer cells. Also by T helper cells weaker antiviral action, more of a role in immunomodulation particularly macrophage activation may be useful in chronic granulomatous disease and osteopetrosis |
Interferon-gamma |
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produced by fibroblasts antiviral actionreduces the frequency of exacerbations in patients with relapsing-remitting MS |
Int Beta |
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produced by leucocytesantiviral actionuseful in hepatitis B & C, Kaposi's sarcoma, metastatic renal cell cancer, hairy cell leukaemiaadverse effects include flu-like symptoms and depression |
Int alpha |
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Ifn receptors |
IFN-alpha and IFN-beta bind to type 1 receptors whilst IFN-gamma binds only to type 2 receptors. |
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BROWN SEQUARD |
Ipsi dorsal & pyramidal contra spino thalamic |
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ADH site of action |
promotes water reabsorption in the collecting ducts of the kidneys by the insertion of aquaporin-2 channels. |
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ADH site of action |
promotes water reabsorption in the collecting ducts of the kidneys by the insertion of aquaporin-2 channels. |
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second-wind' phenomenon and present with distal muscle cramping Second wind - a person's ability to breathe freely during exercise, after having been out of breath |
McArdle |
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Glycogen storage diseases |
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Hypoglycemia GSD |
Von Gierek |
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cardiomyopathy and severe, generalised muscular hypotonia |
Pompes disease |
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anaphylaxis key cytokine |
histamine |
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sister chormatids moving opposite ends of cell |
anaphase (on (an-aphase) their way) |
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middle of the cell (chromosomes) |
metaphase |
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chrkmatids arrrive at opposite ends |
telophase (telephone to say they arrived) |
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Thick Asc limb |
Reabsorption of Na. K. Cl |
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Microtubules function |
Microtubules help guide movement during intracellular transport and also help bind internal organelles |
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docking and fusion. |
Proteins called SNAREs on the surface of vesicles and their target organelles facilitate docking and fusion. |
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smooth endoplasmic reticulum synthesises |
the lipid membrane. |
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5FU moa |
Pyrimidine analogue inducing cell cycle arrest and apoptosis by blocking thymidylate synthase (works during S phase) |
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6MP |
Purine analogue that is activated by HGPRTase, decreasing purine synthesis |
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cytarabine |
Pyrimidine antagonist. Interferes with DNA synthesis specifically at the S-phase of the cell cycle and inhibits DNA polymerase |
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cardiac ap |
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cardiac ap Calcium in |
phase 2 |
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Cardiac ap sodium in |
phase 0 |
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carfiac ap phase 2 |
ca in. k out |
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cadiac ap. k out |
1,2,3,4 |
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cardiac ap.. diastole |
4 phase |
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Protein degradation |
recognition by ubiquitin digestion by proteasome |
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