Clinical Chemistry - Chapter 15 - Lipids And Lipoproteins

Front 1

Describe the structure of fatty acids:

Back 1

linear chains ofcarbon-hydrogen bonds terminating in carboxyl group

Front 2

Describe the structure of triglycerides:

Back 2

3 fatty acid moleculesattached to 1 molecule of glycerol by ester bonds

Front 3

Describe the structure of phospholipids

Back 3

glycerol backbone andphospholipid head

Front 4

Describe the structure of cholesterol

Back 4

unsaturated steroid alcoholcontaining 4 rings & single side chain tail

Front 5

Describe the structure of lipopoteins:

Back 5

lipids + proteins

Front 6

Chylomicrons

Back 6

largest and least dense; producedby intestine; deliver dietary lipids to hepatic and peripheral cells

Front 7

VLDL

Back 7

produced by liver; majorcarriers of endogenous triglycerides

Front 8

LDL

Back 8

form as a result oflipolysis of VLDL; readily taken up by cells via LDL receptors in liver &peripheral cells

Front 9

HDL

Back 9

smallest & most dense;synthesized by liver & intestine; capable of removing excess cholesterolfrom peripheral cells

Front 10

Lipoprotein X

Back 10

Abnormal lipoprotein,patients with biliary cirrhosis or cholestasis; LCAT mutations

Front 11

What are the pathways in lipoprotein metabolism?

Back 11

lipid absorption, exogenous pathway, endogenous pathway, reverse cholesterol transport pathway

Front 12

Arteriosclerosis

Back 12

caused by lipids, in formof esterified cholesterol, being deposited in artery walls, resulting in fattystreaks, which develop into plaques that can block blood flow

Front 13

An elevation of Lp (a) poses an increased risk of:

Back 13

CHD and cerebrovascular disease