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13 Cards in this Set

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Describe the structure of fatty acids:

linear chains ofcarbon-hydrogen bonds terminating in carboxyl group

Describe the structure of triglycerides:

3 fatty acid moleculesattached to 1 molecule of glycerol by ester bonds

Describe the structure of phospholipids

glycerol backbone andphospholipid head

Describe the structure of cholesterol

unsaturated steroid alcoholcontaining 4 rings & single side chain tail

Describe the structure of lipopoteins:

lipids + proteins


largest and least dense; producedby intestine; deliver dietary lipids to hepatic and peripheral cells


produced by liver; majorcarriers of endogenous triglycerides


form as a result oflipolysis of VLDL; readily taken up by cells via LDL receptors in liver &peripheral cells


smallest & most dense;synthesized by liver & intestine; capable of removing excess cholesterolfrom peripheral cells

Lipoprotein X

Abnormal lipoprotein,patients with biliary cirrhosis or cholestasis; LCAT mutations

What are the pathways in lipoprotein metabolism?

lipid absorption, exogenous pathway, endogenous pathway, reverse cholesterol transport pathway


caused by lipids, in formof esterified cholesterol, being deposited in artery walls, resulting in fattystreaks, which develop into plaques that can block blood flow

An elevation of Lp (a) poses an increased risk of:

CHD and cerebrovascular disease