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30 Cards in this Set

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Reduction in the number of rbc, hemoglobin or both in the circulating blood

Anemia

Anemia may be associated with

-Decreased rbc production


-inappropriate rbc loss


-increase rbc destruction

Basis of morphological classification

MCV


MCHC


MCH

Average mass of hemoglobin per rbc in a sample of blood

MCH

Measure of concentration of hemoglobin in a given volume of packed rbc. Defined as ratio of weight of hemoglobin to volume of rbc

MCHC

Depression of erythrogenesis

Normocytic, normochromic

Dietary deficiency

Macrocytic, Normochromic

Recovery from large loss of RBC

Macrocytic, hypochromic

Iron deficiency

Microcytic, hypochromic

Follows trauma or surgical procedure, sweet clover, warfarin, or bracken fern

Acute hemorrhage

Anemia manifested immediately until blood volume returns to normal

Peracute hemorrhage

Usually microcytic and hypochromic due to depletion of iron; parasitism, git lesions, bleeding into body cavities

Chronic hemorrhage

Examples of blood loss anemia

Acute hemorrhage


Peracute hemorrhage


Chromic hemorrhage

Blood parasites:

Anaplasma


Piroplasma


Haemobartonella


Eperythrozoon


Viral infections:

EIA

Bacterial infections:

C. Haemolyticum


Leptospira icterohaemorrhagiae

Poisonous plants:

Castor bean


Oak shoot


Wild onions

Chemical agents:

Copper


Lead


Phenothiazine


Methylene blue

Metabolic diseases

-Immunohemolytic ds. Of newborn


-autoimmune hemolytic anemia

Increase erythrogenesis in response to anemic process, high porphyrin induces defect in synthesis of heme, rbc defective and susceptible to hemolysis

Porphyria in cattle

Severe anemia due to hemolysis or hemorrhage (def in pyruvate kinase-energy metabolism)



-with remarkable nucleated rbc, reticulocytes, polychromasia, anisocytosis, poikilocytosis

Familial anemia im Basenji dogs

Stomatocytosis

Hemolytic anemia in chondrodysplastic malamute

Is irregular clump of ribosomal RNA and organelles like mitochondria

Reticulum

Irregular net-like structures in polychromatoohils

Reticulocytes

Decreased production of rbc caused vy inadequate production of RBC by the bone marrow

Non regenerative anemia

Species where reticulocytes when stained with new methylene blue AGGREGATES ONLY

Canine

Average size/volume of rbc

MCV

MCV means

Mean corpuscular volume

MCH means

Mean corpuscular hemoglobin

MCHC means

Mean corpuscular hemoglobin concentration