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11 Cards in this Set
- Front
- Back
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Products of TCA cycle |
4 e- carriers 1 GTP |
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Pyruvate dehydrogenase |
Facilitates conversion of pyruvate to acetyl CoA |
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Coenzymes to pyruvate dehydrogenase |
TPP, Lipoic acid, CoA, NAD, FAD |
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First reaction of the TCA cycle |
Oxaloacetate + acetyl CoA --> citrate Catalyzed by citrate synthase |
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Aconitase |
Catalyzes conversion of citrate to isocitrate |
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isocitrate dehydrogenase |
Catalyzes conversion of isocitrate --> oxalosuccinate --> a-ketoglutarate. Produces an NADH and CO2 in the process |
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a-ketoglutarate dehydrogenase |
a-ketoglutarate + NAD+ + CoA --> succinyl CoA + CO2 + NADH |
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Succinyl CoA synthitase |
Catalyzes succinyl CoA + Pi + GDP --> succinate + GTP |
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Succinate dehydrogenase |
Succinate --> fumerate Enzyme found in the mitrochondrial inner membrane, part of the ETC |
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Fumerase |
Fumerate --> Malate |
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Malate dehydrogenase |
Malate --> Oxaloacetate to restart the cycle Not energetically favorable, but citrate reaction is highly favorable so product is quickly used up |
