Chromosome Mutation Practice Problems

Front 1

Identify the chromosome aberration that increases the genetic material on a particular
chromosome

Back 1

Insertion/duplication

Front 2

Identify the chromosome aberration that decreases the genetic material on a particular
chromosome

Back 2

deletion AKA deficiency

Front 3

Identify the chromosome aberration that changes the position of genetic material
within a chromosome without altering the amount of genetic material carried by the
chromosome

Back 3

inversion

Front 4

Identify the chromosome aberration that shifts genetic material from one chromosome
to a non-homologous chromosome.

Back 4

translocation

Front 5

In diploids, a single recessive allele can end up being expressed in diploids via two
mechanisms

Back 5

pseudodominance, genomic imprinting, X-linkage

Front 6

Identify the chromosome aberration that causes genes to move from one linkage
group to another

Back 6

translocation

Front 7

The phenomenon whereby changing the position of a gene within the genome affects
its pattern of expression

Back 7

position effect variegation. PEV

Front 8

The type of chromatin that can prevent gene expression

Back 8

heterochromatin (AKA closed)

Front 9

When a recessive allele is expressed in the phenotype because a deletion removed the second copy of the gene.

Back 9

pseudodominance

Front 10

Inversion that involves the centromere is called...

Back 10

pericentric

Front 11

inversion that does not involve the centromere is called...

Back 11

paracentric

Front 12

Indicate the two rearrangements where there is no change in the total amount of genetic material

Back 12

inversion and translocation

Front 13

Inversions are often called...

Back 13

crossing over suppressor

Front 14

A chromosome with two centromeres

Back 14

dicentric

Front 15

A chromosome with no centromere

Back 15

acentric

Front 16

A translocation leading to the fusion of two chromosomes

Back 16

Robertsonian

Front 17

If a translocation breakpoint is close to or within genes, a new ______ can be created.

Back 17

hybrid gene

Front 18

Somatic translocations have often been associated with specific types of ______ in humans.

Back 18

cancer

Front 19

Inversions and translocations can participate in the ______ process during evolution.

Back 19

speciation

Front 20

Individual with balanced translocations are usually viable but very often are identified because the are ______.

Back 20

sterile

Front 21

A karyotype with 2n-1 is called

Back 21

monosomy

Front 22

A karyotype with 2n+1 is called

Back 22

trisomy

Front 23

A deviation from normal diploidy is called

Back 23

aneuploidy

Front 24

Monosomy and trisomy are the result of _____ during either meiosis I or II.

Back 24

non-disjunction.