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11 Cards in this Set
- Front
- Back
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What are inhibitors defined as? |
Molecules that cause a loss of catalytic activity. |
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What enzyme-level function do inhibitors serve? |
The prevention of substrates fitting into the active sites of the enzyme |
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What is the one thing that reversible inhibitors can't do? |
Form covalent bonds with an enzyme |
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Reversible inhibitors may be competitive or noncompetitive. What does this mean? |
They may compete with the substrate for the active site or they may act on another site |
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What is a competitive inhibitor similar to, chemical-structure-and-polarity wise? |
The substrate |
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How are the effects of a competitive inhibitor reversed? |
By increasing the substrate concentration |
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What function does the competitive inhibitor, antimetabolite, serve? |
The treatment of some bacterial infections |
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Sulfanilamide competes with p-aminobenzoic acid in the growth cycle of bacteria. What is the 4-letter abbreviation for p-aminobenzoic acid? |
PABA |
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How does a noncompetitive inhibitor prevent the catalyzing of a reaction? |
By changing the shape of the enzyme |
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The effects of some inhibitors are irreversible. What is the effect of an inhibitor covalently bonding with R groups of an amino acid near the active site? |
Enzyme activity is destroyed |
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Generally speaking, how is a non-competitive inhibitor reversed? |
By a chemical process that removes the inhibitor |
