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26 Cards in this Set

  • Front
  • Back
creatinine is formed from the
oxidation of creatine
creatinine is considered the substance of choice to mz endogenous real clearance because
it is completely filtered by the glomeruli
which statement is true about creatinine
high serum levels results from reduced glomerular filtration rates
which of the formula below is the correct expression of creatinine clearance
CC = U/P x V x 1.73/A
a sample of amniotic fluid collected for fetal lung studies from a woman w/ a pregnancy compromised by hemolytic disease of the newborn (HDN) has a creatinine of 88 mg/dL, what is the most likely cause of this result
fluid is urine from accidental puncture of the urinary bladder
which analyte should be reported as a ratio using creatinine concentration as a reference
urinary microalbumin
urea is producd from
the catabolism of proteins & amino acids
urea concentration is calc from the BUN by mx by a factor of
BUN 2.14
Urea = BUN x (1/.467) = 2.14
a patient BUN is 60 mg/dL & serum creatinine is 3.0 mg/d: the results suggest
prerenal failure
urinary urea mz may be used for calc of
nitrogen balance
BUN is determined electrochemically by coupling the urease reaction to mz of
the time rate of increase in conductivity
in the UV enzymatic method for BUN, the urease reaction is coupled to a second emz rtx using
glutamate dehydrogenase
which produce is mz in coupling step of the urease-UV method for BUN
NAD+
which emz defency is responsible for phenylketonuria (PKU)
phenylalanine hydroxylase
which of the following condtx is classified as a renal type aminoaciduria
Fanconi's syndrome
which aminoaciduria results in the overflow of branched chained amino acids
maple syrup urine disease
which of the following best describe the Guthrie test
bioassay for PKU dependent upon the phenylalanine requirement of B. subtilis
of the method used to measure amino acids, which is capable of mz only phenylalanine
flurometric analysis w/ ninhydrin
blood ammonia levels are usually mz in order to eva
hepatic coma
enzymatic mz of ammonia requires which of the following substrates & coemz
a-Ketoglutarate (substrate)
NADH (coemz)
which of the following is true about ammonia
hepatic coma can results from Reye's syndrome
a sample for ammonia assay is taken from an IV line that has been capped & injected w/ lithium heparin (called heparin lock), the sample is drawn in a syringe containing lithium heparin & immediately capped & iced. the plasma is separated & analyzed w/in 20 mins of collection & the results is 50 ug/dL -- higher than one mz 4 hours ago, why?
stasis of blood in the line caused increase ammonia
uric acid is derived from the
catabolism of purines
which of the following condtx is ass w/ hyperuricemia
renal failure
order for uric acid are legitimate stat request because
levels above 10 mg/dL causes urinary tract calculi
which uric acid method is ass w/ negative bias caused by reducing agents
uricase coupled w/ the Trinder reaction