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26 Cards in this Set
- Front
- Back
creatinine is formed from the
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oxidation of creatine
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creatinine is considered the substance of choice to mz endogenous real clearance because
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it is completely filtered by the glomeruli
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which statement is true about creatinine
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high serum levels results from reduced glomerular filtration rates
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which of the formula below is the correct expression of creatinine clearance
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CC = U/P x V x 1.73/A
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a sample of amniotic fluid collected for fetal lung studies from a woman w/ a pregnancy compromised by hemolytic disease of the newborn (HDN) has a creatinine of 88 mg/dL, what is the most likely cause of this result
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fluid is urine from accidental puncture of the urinary bladder
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which analyte should be reported as a ratio using creatinine concentration as a reference
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urinary microalbumin
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urea is producd from
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the catabolism of proteins & amino acids
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urea concentration is calc from the BUN by mx by a factor of
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BUN 2.14
Urea = BUN x (1/.467) = 2.14 |
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a patient BUN is 60 mg/dL & serum creatinine is 3.0 mg/d: the results suggest
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prerenal failure
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urinary urea mz may be used for calc of
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nitrogen balance
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BUN is determined electrochemically by coupling the urease reaction to mz of
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the time rate of increase in conductivity
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in the UV enzymatic method for BUN, the urease reaction is coupled to a second emz rtx using
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glutamate dehydrogenase
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which produce is mz in coupling step of the urease-UV method for BUN
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NAD+
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which emz defency is responsible for phenylketonuria (PKU)
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phenylalanine hydroxylase
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which of the following condtx is classified as a renal type aminoaciduria
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Fanconi's syndrome
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which aminoaciduria results in the overflow of branched chained amino acids
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maple syrup urine disease
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which of the following best describe the Guthrie test
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bioassay for PKU dependent upon the phenylalanine requirement of B. subtilis
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of the method used to measure amino acids, which is capable of mz only phenylalanine
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flurometric analysis w/ ninhydrin
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blood ammonia levels are usually mz in order to eva
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hepatic coma
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enzymatic mz of ammonia requires which of the following substrates & coemz
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a-Ketoglutarate (substrate)
NADH (coemz) |
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which of the following is true about ammonia
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hepatic coma can results from Reye's syndrome
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a sample for ammonia assay is taken from an IV line that has been capped & injected w/ lithium heparin (called heparin lock), the sample is drawn in a syringe containing lithium heparin & immediately capped & iced. the plasma is separated & analyzed w/in 20 mins of collection & the results is 50 ug/dL -- higher than one mz 4 hours ago, why?
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stasis of blood in the line caused increase ammonia
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uric acid is derived from the
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catabolism of purines
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which of the following condtx is ass w/ hyperuricemia
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renal failure
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order for uric acid are legitimate stat request because
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levels above 10 mg/dL causes urinary tract calculi
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which uric acid method is ass w/ negative bias caused by reducing agents
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uricase coupled w/ the Trinder reaction
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