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29 Cards in this Set
- Front
- Back
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Jones oxidation - R, P, C (reactants, products, conditions)? |
Alcohol to carbonyl, PCC |
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DCC is used to activate _ for the formation of... |
DCC activates carboxylic acids for ester or amide formation |
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From carboxylic acid to ketone, conditions? |
1) CH3NH(OCH3), DCC 2) CH3MgBr |
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Aldehyde to ketone? |
CH3MgBr, PCC |
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Oxymercuration conditions |
Hg(OAc)2, H+/H2O |
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Acid chloride to ketone (w methyl substituent)? |
CH3Li, CuBr |
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Ozonolysis? |
O3 and solvent MeOH |
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Double reduction of ester to alcohol? |
LiAlH4 |
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Single reduction of ester to aldehyde? |
DIBAL-H |
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Ester to carboxylic acid, name and conditions? |
Saponification; KOH and H2O |
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Conversion of carboxylic acid to acid chloride? |
SOCl2 |
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Substitution of Cl on acid chloride for diethylamine? |
(CH3)2NH |
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Wolff-Kishner Reduction: R, P, C? |
Ketone and H2N-NH2 in KOH, makes CH2 out of ketone |
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Hydroboration-oxidation conditions? Where does BH3 add first? |
BH3, H2O2/NaOH; BH3 first adds to the less substituted side of the double bond |
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Addition of Br to benzene? |
Br2, FeBr3 |
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Addition of aldehyde to aromatic ring? |
Acid chloride + FeCl3 |
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Conversion of NO2 group to ether? |
1) Fe/Hcl, 2) NaNO2/MeOH |
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Reduce aldehyde to primary alcohol on ring? |
NaBH4 |
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Add NO2 group to ring? |
HNO3, H2SO4 |
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Addition of alkyl group to hydroxyl group on ring? |
PBR3, X-MgBr |
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Conversion of terminal DB to carboxylic acid? |
1) BH3, 2) CrO3 H3O+ |
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Ethylene Glycol and HCl addition to carbonyl? |
Creation of 5 membered ring with 2 oxygens symmetrical |
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What can you use to protect a hydroxyl group from attack? With what do you ultimately remove this? |
THP; removed with acid and water |
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What does MCPBA do? |
Turns a double bond into an epoxide |
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Formation of acetal: R, P, C? |
Carbonyl, make acetal; ROH and acid |
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Formation of imine: R, P, C? |
Carbonyl, primary amine, acid |
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Formation of enamine: R, P, C? |
Carbonyl, secondary amine, acid |
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Acid-catalyzed esterification: R, P, C? |
Carboxylic acid, makes ester, need ROH group and acid |
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Haloform reaction: R, P, C? |
Carbonyl, makes carboxylic acid, need Br3 and NaOH |
