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18 Cards in this Set
- Front
- Back
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Indications for diuretic use (6) |
- edema associated with CHF - acute pulmonary edema - liver disease - renal disease - hypertension - conditions that cause hyperkalemia |
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Thiazide and thiazide like diuretics action and indication |
Block the chloride pump Keep the chloride sodium in the tubule to be excrete in the urine, thus preventing the reabsorption of both in the vascular system Treatment of edema associated with CHF, liver or renal disease Mono therapy or adjuncts for the treatment of hypertension |
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Thiazide cautions (3) |
- gout - SLE - diabetes |
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Thiazide adverse effects |
- hypokalemia - decreased calcium excretion - altered blood glucose levels - slightly alkalinized urine |
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Thiazide drug to drug interactions |
- cholestyramine or colestipol - digoxin - anti diabetic agents - lithium
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Loop diuretics |
Furosemide ( lasix) Most commonly used; less powerful than new drugs
Bumetanide ( bumex) Torsemide ( demadex) Are the newer drugs that are more powerful than lasix
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Loop diuretics actions and indications |
Block the chloride pump in the ascending loop of henle, causing reabsorption of sodium and chloride Indications - acute CHF - acute pulmonary edema - edema associated with CHF - edema associated with renal or liver disease - hypertension |
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Loop D. Contraindications and cautions |
- electrolyte depletion - anuria - severe renal failure - hepatic coma
Cautions - SLE - Gout - DM |
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Adverse effects (LD) |
Related to the imbalance in electrolytes and fluid - hypokalemia - alkalosis - hypocalcemia - hypotension - dizziness - hyperglycemia - ototoxicity or deafness, can be reversed when off the medication |
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Drug to drug interactions ( LD) risk of ototoxicity |
- amino glycosides and cisplatin - anticoagulation - ibuprofen, NSAIDS, salicylates, indomethacin |
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Carbonic anhydride inhibitors actions and indications |
Blocks the effects of carbonic anhydrase , slowing down the movement of hydrogen ions
Indications: adjunct to other diuretics Glaucoma |
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Carbonic inhibitors contraindications and cautions |
- angle closure glaucoma Cautions - fluid or electrolyte imbalances - renal or hepatic disease - adrenocortical insufficiency - respiratory acidosis - COPD |
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Thiazide and thiazide like diuretics prototype drug |
Hydrochlorothiazide |
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Loop diuretics prototype drug |
Furosemide (lasix) |
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Carbonic anhydrase inhibitors prototype drug |
Acetazolamide |
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Spironolactone is the drug of choice for treating |
Hyper aldosterone |
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Mannitol |
The only osmotic diuretic |
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Osmotic diuretics indications |
Used in acute eye situations or during acute attacks of glaucoma Cranial pressure, ARF due to shock, trauma, or overdose |
