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83 Cards in this Set

  • Front
  • Back

What is the cell theory

-The cell is the smallest unit of life


- all organisms are made of one or more cells


-cells only arise from other cells

What does the cells shape reflect?

Its function

This is the

Nucleus

What is the largest organelle

The nucleus

What is the function of the nucleus

Genetic control center; directs protein synthesis

What is the rough ER composed of

Extensive sheets and covered with ribosomes

What is the composition of Smooth ER

Branching tubules with no ribosomes (smooth surface)

What is the function of Rough ER

Protein synthesis and manufacture of cellular membrane

The function of Smooth ER

Lipid synthesis, detoxification, calcium storage

Ribosomes

Small dark granules free in cytosol or on surfaces of Rough ER

What is the function of ribosomes

Interpret genetic code and synthesize polypeptides

Golgi complex

Several closely spaced parallel cisternae with thick edges

what is the function of the golgi complex

-Packages, modifies and separates proteins for secretion from cell.


- modifies carbohydrates on proteins

lysosomes

membranous sacs containg acid hydrolases

what is the function of lysosomes

sites of intracellular digestion

peroxisomes

membranous sacs containing catalase and oxidase enzymes

in what organs are peroxisomes abundant in?

the liver and kidney

what are the functions of peroxisomes

detoxification, most important enzyme catalase breaks down hydrogen peroxide

mitochondrion

Rodlike, double membrane structures; inner membrane folded into projections called cristae

what is the function of the mitochondria?

site of ATP synthesis; powerhouse of the cell

what is the function of inclusions

storage for nutrients, waste and cell products

centrioles

paired cylindrical bodies, each composed of nine triplets of microtubles

what are the functions of centrioles

-organize microtubule work


-form the spindle as asters during mitosis


- form the bases of flagella and cilia

microtubules

cylindrical structures made of tubulin proteins

what is the function of microtubules

-support the cell and give it shape


-involved in intracellular and cellular movement


-form axonemes (stalk) of cilia and flagella

what is the function of the cell membrane

barrier, communication, transport,

what is the cell membrane composed of

lipids and proteins

the heads of phospholipids are _________ and are attracted to _________

polar; water

the tails of phospholipids are __________ and avoid ____________

nonpolar; water

the head of phospholipids lie on both the __________ and _________ surfaces while the tails line up in _____________

inner, outer, the center

cholesterol has both a

polar (hydoxyl group) and nonpolar (fused ring system) region

what does cholesterol do for the cell membrane

stiffens it

integral proteins have both

hydrophilic and hydrophobic regions



Transport

the functions of transport

hydrolyze ATP as an energy source to actively pump substances across membrane

receptors for signal transmission

function of receptors

a membrane protein outside of cell with a specific shape that matches the shape of a chemical messenger

enzymatic activity

function of the enzymatic activity

catalyzes sequential steps of metabolic pathway

cell-cell recognition

function of cell-cell recognition

glycoproteins serve as identification tags

cytoskeleton and extracellular matrix (ECM)

functions of ECM

helps maintain cell shape, cell movement, and fixes location of certain membrane proteins



cell-cell joining

functions of cell-cell joining

cell adhesion molecules (CAMs) provide temporary binding sites that guide cell migration

what makes peripheral proteins different from integral proteins?

they are not embedded in lipid bilayer

function of peripheral proteins

-helps support membrane from cytoplasmic side


-change shape of cell during cell division and muscle contraction

glycocalyx is found

on the surface of animal cells

what is glycocalyx composed of?

carbohydrate portions created by sugars of glycoproteins and glycolipids

function of glycocalyx

-gives identity of molecules


-immune system recognition


-cell communication by chemical signals

Vesicular Transport

transport of large particles and uses ATP

Exocytosis

V-transport out of cell

endocytosis

V-transport into cell

phagocytosis meaning and function

cell eating- keeps tissue free of debris and infectious microorganisms

steps of phagocytosis

1) cell engulfs large particle by forming a projecting pseudopod (false foot)


2) gets enclosed with membranous sac called phagosome


3) phagosome combines with lysosome and is ingested

pinocytosis meaning and function

cell drinking- cell "gulps" drops of extracellular fluid containing solutes into tiny vesicles

Process of exocytosis

Process of exocytosis

1) membrane bound vesicle migrates to the plasma membrane


2) v-SNAREs bind with t-SNAREs


3) vesicle and plasma membrane fuse and a pore opens up


4)vesicle contents are released to the cell exterior

2nd messenger system 

2nd messenger system

messenger binds to surface receptor (1)


receptor activates G protein that is linked to (2)


G protein binds to enzyme, adenylate cyclase which converts ATP ---> cAMP the second messenger (3)


cAMP activated a kinase in cytosol (4)


kinase activates or inactivates other enzyme triggering physiological changes in cell (5)

where us microvilli located

surface of absorptive cells such as intestinal and kidney tubule cells

function of microvilli

shapes cell and increases plasma membrane surface area

what are cilia and flagella made of

centrioles that form base (basal bodies), 2 microtubules that form axoneme (stalk), and arms are composed of protein

function of cilia

moves mucous and trapped substances across surface

flagella

only found in sperm; provides movement

protein synthesis

involves (a) transcription, synthesis of complementary mRNA and (b) translation "reading" of the mRNA by tRNA and peptide bonding of amino acids into polypeptide

what coordinates translation?

ribosomes

microfilaments

form a net work on cytoplasmic side of plasma membrane called membrane skeleton

function of microfilaments

supports phospholipids and microvilli and provides cell movement

function intermediate fibers

help hold epithelial cells together


resist stress on cells


line nuclear envelope


toughens hair and nails (ex: keratin)

funtion of microtubules

hold organells in place


maintians cell shape


guides organells and molecules


from stialk of cilia and flagella

Steps of Cell cycle

-G1 phase the first gap phase:


cell is syntehsizing proteins and growing rapidly


centrioles start to replicate to prepare for cell division


-S phase synthesis phase:


DNA is replicated


-G2 phase, second gap phase:


enzymes needed for division are syntehsized and moved to proper sites


-M phase, miotic phase: prophase, metaphase, anaphase, telophase


G0 phase- cells that left cycle

during mitosis cells

divide into 2 daughter cells with indentical copies of DNA

funtion of mitosis

generates new cells for growth and repair

steps of mitosis

1) prophase


2) metaphase


3) anaphase


4) telophase

in what phase do centromeres split in 2

anaphase

cytokinesis is the division of the

cytoplasm

sequence of cytokinesis

myosin pulls in microfilaments


this causes crease aroung the cel equator


cell pinches into two


interphase has begun

creasing around the cell equator is called

cleavage furrow

autolysis

self digestion of dead or degenrate cells

when does autolysis happen

when lysosomes rupture

what can cause a lysosome to rupture

lack of O2


cell is injured


excessive amount of vitamin A

apoptosis

"falling away" or programmed cell death

apoptosis occurs

when body of cells are programmed to have limited life span

what is an example of apoptosis?

menstraul cycle