Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
8 Cards in this Set
- Front
- Back
Where does erythropoiesis take place in the fetus
|
first in the yolk sac, then in the liver, and some in the spleen - by the 5th month of gestation it begins to move to the bone marrow
|
|
Fetal hemoglobin
|
has more affinity to oxygen than adult hemoglobin so the fetal blood is able to grab oxygen off of maternal hemoglobin as it goes through the placenta
|
|
The fetus and neonate have an increased number
|
of RBC's - their breakdown after birth releases hemoglobin which converts to bilirubin - sometimes at a rate too fast for the liver to conjugate into water-soluble "direct" bilirubin that can be excreted in the urine - this can result in jaundice and sometimes kernicterus
|
|
Hemolytic disease of the newborn
|
results in an incompatibility between the maternal and fetal blood which involves differences in Rh factors and sometimes ABO blood type - maternal antibodies cross the placenta and hemolyse fetal erythrocytes
|
|
Sickle cell anemia and thalassemia
|
can come from an inherited abnormality of hemoglobin structure
|
|
G6PD deficiency and hereditary spherocytosis
|
are other inherited abnormalities
|
|
At birth the lymphocyte count
|
is naturally high
|
|
Childhood leukemia
|
is probably the result of multiple interactions between hereditary predisposition and environmental factors
|