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57 Cards in this Set

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Arteries

Carry blood away from the ❤️

Veins

Carry blood toward the ❤️

_________ the site of gas exchange & nutrients passing into the tissue space for cellular needs.

Capillaries

Tunic Layers

Interna/Intima Layer


Media Layer


External Layer

I


M


E

Interna/Intima Layer

The innermost Layer lining the lumen with squamous shape endothelial cells

“Internal”

Media Layer

Comprised of elastic fibers and smooth muscle which is innervated by the sympathetic nervous system for control of vasoconstriction and vasodilation

“Middle”

Externa Layer

Collagen Fibers that protect and reinforce vessels

“External”

Lumen

Central blood-containing space surrounded by the tunics

Both arteries and veins contain ____________________ however they may differ in the amount or quantity of specific layer of tissue(s) such as the tunica media or smooth muscle

All 3 tunic layers

Capillaries??

Smallest blood vessels

________ walls consist of single cell thickness of endothelial cells.


Only allow a single RBC to pass at a time

Capillaries

3 types of capillaries

Continuous


Fenestrated


Sinusoids

C


F


S

Continuous

Found in skin and muscles


Uninterrupted lining of tight junctions


Intercellular cleft spaces allow for the passage of fluids and solubilized products within the fluids

Fenestrated

Found in small intestines, endocrine glands, kidneys.


Endothelial lining consist of pores for greater permeability

Sinusoids

Found in liver, bone marrow, lymphoid tissue.


Very leaky endothelium to allow for passage of large molecules such as proteins and blood cells.

Vascular Shunt

Channel Connecting an arteriole directly w/ a venule (vein) through the capillary bed

Pre-capillary Sphincter

Band of smooth muscle surrounding a true capillary


Under stimulation by the sympathetic nervous system contracts the smooth muscle band to shunt blood from non-vital areas to areas where oxygenated blood is in more demand

Veins have large capacitance vessels w/ __________ walls than arteries, designed to return blood to the ❤️

THINNER

Veins contain “________” to prevent the back flow of blood

Valves

Blood pressure

Force exerted on the wall of blood vessels



Provides the driving force to keep blood moving

Varicose veins

Dilated and painful veins due to incompetent (leaky) valves

Venous BP alone is too low to promote adequate blood return and is aided by?

Respiratory “pump”


Muscular “pump”


Sympathetic venoconstriction

R


M


SVC

Respiratory “pump”

Pressure changes created during breathing

Muscular “pump”

Contraction of skeletal muscles “milk” blood towards the ❤️

Muscular “pump”

Contraction of skeletal muscles “milk” blood towards the ❤️

Sympathetic Venoconstriction

Under sympathetic control, smooth muscles constrict, pushing blood back toward the ❤️

Resistance

Opposition to blood flow

Sources of resistance are ...?

Blood Viscosity


Total blood vessel length


Blood vessel diameter

Viscosity & blood vessels length remain relatively __________ however changes in vessels diameter frequently alter peripheral resistance

Constant

Larger Diameter = ? = ?

Lower resistance


Decreased BP

Smaller diameter = ? = ?

Greater resistance


Increased BP

Systemic BP

Pressure exerted on arterial walls during ventricular contraction.


Highest pressure is in the aorta and zero pressure in the right atrium

Diastolic BP

Pressure exerted on arterial walls during ventricular relaxation

Capillary pressure ranges from _____ -> ______ mm Hg

20-40 mmHg


Enough pressure to drive nutrients and gases into the tissue space but not high enough to rupture the thin endothelial walls

Lacerated “veins” have a smooth blood flow while lacerated arterial blood flows in spurts. This is due to?

Varying degrees of pressure in each conduit

Maintaining blood pressure

Cardiac output


Peripheral resistance


Blood volume

CO


PH


BV

Short term control of BP

Mediated through the sympathetic nervous system by altering vessel diameter there for resistance

Vasoconstriction = ? = ?

Increased Resistance


Higher BP

Vasodilation = ? = ?

Decreased resistance


Lower BP

“Short term control” originates out of the?

“vasomotor center “

Vasometer center

Sympathetic neurons in the medulla of the brain stem which regulates blood vessel diameter

Cardiovascular center

Also located in the medulla or brain stem


Controls BP by altering CO and blood vessel diameter, consists of the “ Cardioacceleratory Center” and the “Cardiohibitory Center” to speed up and slow down heart rate respectively

Long term control of BP

Altering blood volume (“direct renal mechanism”) or regulated through releases of hormones from the kidneys which is the “indirect renal mechanism”


Indirect process is thru the release of hormones


Renin -> Angiotensin 2 -> aldosterone -> ADH

Angiotensin 2

Vasoconstrictor (^ resistance to blood flow and BP)

Aldosterone

Regulates electrolytes and will preserve more sodium (& potassium) in the body therefor keep more water in the body as well, ^ BP

Aldosterone stimulates ADH

Which decreases urine excretion and builds up fluid volume

Hypotension

Low BP w/ systolic pressure below 100 mmHg

Orthostatic hypotension

Temporary low BP related to posture or suddenly rising from a seated or lying position

Hypertension

Sustained elevated BP


“Silent killer”

Chronic elevated BP is major cause of ...

Heart disease


Renal failure


Vascular disease


stroke

Primary Hypertension

Elevated BP NOT associated w/ an identifiable particular cause

Risk factors for primary hypertension

Obesity


Age


Race


Hereditary


Stress factors


Smoking

Secondary hypertension

Hypertension due to an identifiable disorder such as excessive renin excretion, arteriosclerosis & endocrine disorders

Circulatory shock

Any condition in which blood vessels are inadequately filled and blood cannot circulate normally


Hypovolemic


Vascular


Cardiogenic

Hypovolemic shock

Large scale blood loss

Vascular shock

Poor circulation resulting from extreme vasodilation

Cardiogenic shock

Heart cannot sustain adequate circulation