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13 Cards in this Set

  • Front
  • Back

Primary Response

response of body to first contact with antigen

Secondary Response

(memory response)


Response of host upon second exposure to an antigen


A more intesive response characterized by high titer of IgG


Based on presence of Memory cells

Cytokines

Signaling molecules

T cells 2 kinds

Helper T cells (CD4, Th)


Cytotoxic T cells (CD8, Tc)

Helper T cells

prodice cytokines to stimulate Tc sells, activate macrphages, and stimulate B cells

Cytotoxic T cells

Destroy target cells with perforin

antigen presenting cell (APC)

ingests, processes and displays antigens on its surface


Macrophages and dendritic cells serve as APC


Antigens are dislayed in association with a "self" molecule called MHC (major histocompatibility complex)

activated macrophages

macrophages stimulted by ingesting Ag or by cytokines

Natural killer cells

lymphocyts that destroy virusinfected cells + tumor cells

interrelationship of cell mediated and humoral immunity

although considered two seperate branches, the humoral immune system and cell-mediated system funstion in concert


T cells help stimulate B cells to produce Ab


antibody-dependent Cell-Mediated Cytotoxicity(ADCC)

what is the difference

i dont know

T dependent antigens

require a TH cell for antibodies

T independent antigens

antigens that stimulate B cell directly without help of T cells