Chapter 17

Front 1

Loading dose

Back 1

A larger dose that brings the patient to an effective drug concentration with great rapidity.

Front 2

Rights of medication administration (5 of them)

Back 2

1. Right patient

2. Right drug

3. Right dose

4. Right route

5. Right time

Front 3

Pediatric dosing is strictly based on what?

Back 3

Weight

Front 4

Gram (g) = how many milligrams?

Back 4

Gram=1000 mg

Front 5

A Liter is equal to

Back 5

1000mL, slightly more than 1 quart, or the capacity occupied by 2.2 pounds of distilled water add 39.2ﾟC.

Front 6

Cp

Back 6

Desired plasma concentration

Front 7

CL

Back 7

The ratio between the rate of elimination to the plasma concentration of the drug.

Front 8

F

Back 8

Bioavailability (F=1 in IV applications)

Front 9

Vd

Back 9

Volume of Distribution

Front 10

If the patient has some sort of liver or kidney disorder what happens to the maintenance dose and loading dose?

Back 10

The maintenance dose decreases and the loading dose stays the same.

Front 11

Oxygen

Back 11

Given to all patients with angina pectoris. Causes vasodialation and protects the tissues from hypoxia.

Front 12

Epinephrine

Back 12

A sympathetic drug use to manage cardiac arrest because it increases heart contractibility.

Front 13

Isoproterenol (Isuprel)

Back 13

Produces an overall increase in heart rate and myocardial contractibility but newer agents have replaced it in most clinical settings.

Front 14

Dopamine (Intropin)

Back 14

Indicated and used in cases with hypotension is less than 90mmHg. It causes vasoconstriction. It should be used at the lowest dose that produces adequate perfusion of vital organs.

Front 15

Beta blockers (Propranolol, Metroprolol, Atenolol, and Esmolol)

Back 15

Reduce heart rate blood pressure, myocardial contractbility, and myocardial oxygen consumption which makes them effective in the treatment of angina pectoris and hypertension. They are also useful in preventing atrialfibulation, atrial flutter and paroxysmal supra-ventricular tachycardia. Adverse reactions are hypotension congestive heart failure and brochospasm.

Front 16

Lidocaine

Back 16

Lidocaine is the drug of choice for the suppression of ventricular ectopy (a beat located outside the normal conductive system) contractions including ventricular tachycardia and ventricular flutter.

Front 17

Antibiotics

Back 17

Class of drugs that have activity in inhibiting the growth reproduction of bacteria (bacteriostatic) or that are directly toxic to bacteria resulting in cellular death (bactericidal).

Front 18

Palliative care

Back 18

Management of symptoms and prevention of patients suffering is the main goal of medication and life limiting and terminal illnesses.

Front 19

Drug absorption

Back 19

The process of transport of the drug from the sight of administration to the systemic circulation.

Front 20

Drug distribution

Back 20

The process of moving the drug from the bloodstream into the tissues.

Front 21

Volume of Dustribution

Back 21

The ratio between the amount of drug in the body to the plasma concentration.

Front 22

Vd

Back 22

Amount of drug in the body/plasma drug concentration.

Front 23

Low Vd

Back 23

Means the drug stays in the blood.

Front 24

Medium Vd

Back 24

Means the drug distributes in the ECF (extracellular fluid).

Front 25

High Vd

Back 25

Means the drug moves to tissue.

Front 26

Pregnancy (Drug) category A

Back 26

Human studies OK safe

Front 27

Pregnancy drug category B

Back 27

Studies in pregnant women have failed to demonstrate a risk to the fetus in any trimester.

Front 28

Pregnancy drug category C

Back 28

Potential benefits may (for mom) outweigh possible risks.

Front 29

Pregnancy drug category D

Back 29

Positive human fetal risk but potential benefits may warrant use despite potential risks.

Front 30

Pregnancy drug category X

Back 30

Risks outweigh potential benefits.

Front 31

Pregnancy drug category N

Back 31

Not investigated by the FDA.

Front 32

Intradermal

Back 32

ID the drug is given beneath the epidermis. Mostly used for drug allergy testing and local anesthetics.

Front 33

Examples of topical drug delivery

Back 33

Skin patch, creams, ointment, lotions, eye or nasal drops and inhalers.

Front 34

Buffered tablets

Back 34

A weak acid or base that is added to the medication to moderate the PH of a drug and keep it as close to neutral as possible.

Front 35

Enteric-coated tablets

Back 35

Specific coat that prevents them from dissolving and/or absorbing in the stomach, so the medication stays undissolved until it reaches the small intestine where it is dissolved and absorbed into blood stream.

Front 36

TDDS

Back 36

Transdermal drug delivery systems or transdermal patches.

Front 37

PDR

Back 37

Physicians desk reference.

Front 38

Analgesics

Back 38

A drug acting to relieve pain.

Front 39

Antiemetics

Back 39

A drug to prevent vomiting and/or nausea.

Front 40

Antibiotics

Back 40

A medicine that inhibits the growth of or destroys micro organisms.

Front 41

p.o.

Back 41

Per os (via the mouth)

Front 42

TD

Back 42

Intradermal

Front 43

Pharmacokinetics

Back 43

The branch of pharmacology concerned with the movement of drugs within the body.

Front 44

TCA's

Back 44

Tricyclics antidepressants