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13 Cards in this Set

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Function of Calcium
1.) Nerve impulse transmission
2.) Cofactors of certain enzymes
3.) Coagulation of blood
4.) Skeletal Mineralization
5.) Preserves cell membrane
5 different functions
Calcium homeostasis involves the:
1.) Small intestine
2.) Kidneys
3.) Skeleton
3 different body parts
Why is ionized calcium the best indication of calcium status?
1.) Biologically active
2.) Regulated by PTH and vit D
How is calcium measured in the blood?
Using ion-selective electrodes
Is Phosphate found intracellularly or extracellularly?
Both
How is phosphate measured?
Ammonium Molybdate to form a phosphomybdate complex.
Magnesium function
1.) Enzyme substrate formation
2.) functions as an activator for many enzyme systems
Methods to measure total magnesium serum and plasma?
1.) photometric methods
2.) atomic absorption spectrophotometry
How to detect free magnesium?
Ion selective electrodes with neutral carrier ionophores
What are some functions of PTH?
1.) Stimulates calcium reabsorotion and release of calcium and phosphate from bone.

2.) Stimulates calcium reabsorption and inhibition of phosphate reabsorption from the renal tubules.

3.) Stimulation of renal production of VitD and then increases intestinal absorption of cal and phosphate.
What is Vit D
Major biologically active metabolite of the vit D sterol family
How can we get Vit D
Ingestion, or from the Sun
Role of Vit D in calcium metabolism
1.) Increases absorption of Ca, and Phosphate from GI
2.) enhances the effect of PTH in the nephron to promote RT calcium reabsorption