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182 Cards in this Set

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protein in blood; maintains proper amount of water in the blood

albumin

specific protein (immunoglobin) produced by lymphocytes in response to bacteria, viruses, or other antigens

antibody (Ab)

substance that stimulates the production of an antibody

antigen

white blood cell containing granules that stain blue

basophil

orange-yellow pigment in bile; formed by the breakdown of hemoglobin when red blood cells are destroyed

bilirubin

blood clotting

coagulation

protein that stimulates growth of white blood cells

colony-stimulating factor (CSF)

change in structure and function of a cell as it matures

differentiation

method of separating serum proteins by electrical charge

electrophoresis

white blood cell containing granules that stain red; associated with allergic reactions

eosinophil

immature red blood cell

erythroblast

red blood cell

erythrocyte

hormone secreted by the kidneys; stimulates red blood cell formation

erythropoietin (EPO)

protein that forms the basis of a blood clot

fibrin

plasma protein that is converted to fibrin in the clotting process

fibrinogen

plasma protein

globulin

white blood cell with numbers dark-staining granules (eosinophil, neutrophil, and basophil)

granulocyte

cell in the bone marrow that gives rise to all types of red blood cells

hematopoietic stem cell

blood protein containing iron

hemoglobin

destruction of breakdown of blood

hemolysis

anticoagulant found in blood and tissue cells

heparin

response of the immune system to foreign invasion

immune reaction

protein with antibody activity

immunoglobin

white blood cell

leukocyte

mononuclear leukocyte that produces antibodies

lymphocyte

monocyte that migrates from blood to tissue spaces; works as a phagocyte to engulf foreign material and debris

macrophage

large platelet precursor cell found in the bone marrow

megakaryocyte

leukocyte with one large nucleus that engulfs foreign material and debris

monocyte

pertaining to a cell (leukocyte) with a single round nucleus

mononuclear

immature bone marrow that give rise to granulocytes

myeloblast

granulocytic leukocyte formed in bone marrow; a phagocytic tissue-fighting cell

neutrophil

liquid portion of blood

plasma

removal of plasma from withdrawn blood by centrifuge

plasmapheresis

small blood fragment that collects at sites of injury to being the clotting process

platelet

pertaining to a white blood cell with a multi-lobed; neutrophil

polymorphonuclear

plasma protein; converted to thrombin in the clotting process

prothrombin

immature erythrocyte

reticulocyte

antigen on red blood cells of Rh+ individuals

Rh factor

plasma minus clotting proteins and cells

serum

unspecialized cell that gives rise to mature, specialized forms

stem cell

enzyme that converts fibrinogen to fibrin during coagulation

thrombin

platelet

thrombocyte

base

bas/o

combining form

color

chrom/o

combining form

clotting

coagul/o

combining form

cell

cyt/o

combining form

red, dawn, rosy

eosin/o

combining form

red

erythr/o

combining form

granules

granul/o

combining form

blood

hem/o


hemat/o

combining form

hemoglobin

hemoglobin/o

combining form

same, equal

is/o

combining form

nucleus

kary/o

combining form

white

leuk/o

combining form

one, single

mon/o

combining form

shape, form

morph/o

combining form

bone marrow

myel/o

combining form

neutral

neutr/o

combining form

nucleus

nucle/o

combining form

eat, swallow

phag/o

combining form

varied, irregular

poikil/o

combining form

iron

sider/o

combining form

globe, round

spher/o

combining form

clot

thromb/o

combining form

removal, a carrying away

-apheresis

suffix

immature cell, embryonic

-blast

suffix

abnormal condition of cells

-cytosis

suffix

blood condition

-emia

suffix

giving rise to; producing

-gen

suffix

protein

-globin


-globulin

suffix

pertaining to destruction

-lytic

suffix

derived from; originating from

-oid

suffix

abnormal condition

-osis

suffix

deficiency

-penia

suffix

eat, swallow

-phage

suffix

attraction for (increase in number of cells)

-philia

suffix

carrying, transmission

-phoresis

suffix

formation

-poiesis

suffix

stop, control

-stasis

suffix

cells are unequal in size

anisocytosis

cells have reduced color

hypochromia

cells are large

macrocytosis

cells are small

microcytosis

cells are irregularly shaped

poikilocytosis

cells are rounded

spherocytosis

any abnormal of pathologic condition of the blood

blood dyscrasia

deficiency in erythrocytes or hemoglobin

anemia

most common form of anemia caused by lack of iron

iron deficiency anemia

failure of blood cell production in the bone marrow

aplastic anemia

occurs when stem cells fail to produce leukocytes, platelets, and erythrocytes

pancytopenia

reduction in red cells due to excessive destruction

hemolytic anemia

lack of mature erythrocytes caused by inability to absorb vitamin B12 into the blood stream

pernicious anemia

a special substance that helps absorb vitamin B12 into the blood stream; lacking in people with pernicious anemia

intrinsic factor

hereditary disorder of abnormal hemoglobin producing sickle-shaped erythrocytes and hemolysis

sickle cell anemia

inherited defect in ability to produce hemoglobin, leading to hypochromia

thalassemia

excess iron deposits throughout the body

hemochromatosis

general increase in red blood cells (erythremia); blood is thick/viscous

polycythemia vera

excessive bleeding caused by a hereditary lack of blood clotting factors necessary for blood clotting

hemophilia

multiple pinpoint hemorrhages and accumulation of blood under the skin

purpura

tiny purple or red flat spots appearing on skin; seen in purpura

petechiae

larger blue or purplish patches on the skin seen in purpura

ecchymoses

a condition in which a patient makes an antibody that destroys platelets

autoimmune thrombocytopenic purpura

Ab

antibody

ABO

four main blood types

ALL

acute lymphocytic leukemia

AML

acute myelogenous leukemia

ANC

absolute neutrophil count

bands

immature white blood cells

baso

basophils

BMT

bone marrow transplantation

CBC

complete blood count

CLL

chronic lymphocytic leukemia

CML

chronic myelogenous leukemia

DIC

disseminated intravascular coagulation

bleeding disorder marked by reduction in blood clotting factors due to their use and depletion for intravascular clotting

disseminated intravascular coagulation

diff

differential count

EBV

Esptein-Barr virus

eos

eosinophils

EPO

erythropoietin

Fe

iron

g/dL

gram per deciliter

GVHD

graft-versus-host disease

immune reaction of donor's cells to recipient's tissue

graft-versus-host disease

HCL

hairy cell leukemia

Hct

hematocrit

Hgb/HGB

hemoglobin

H and H

hemoglobin and hematogrit

HLA

human leukocyte antigen

IgA, IgD, IgE, IgG, IgM

immunoglobulins

lymphs

lymphocytes

MCH

mean corpuscular hemoglobin

MCHC

mean corpuscular hemoglobin concentration

MCV

mean corpuscular volume

mono

monocyte

polys, PMNs,PMNLs

polymorphonuclear leukocytes

PT, pro time

prothrombin time

PTT

partial prothrombin time

RBC

red blood cell

sed rate

erythrocyte sedimentation rate

segs

segmented, mature white blood cells

uL

microliter

WBC

white blood cell

WNL

within normal limits

increase in cancerous white blood cells

leukemia

a form of leukemia where immature granulocytes (myeloblasts) predominate

acute myelogenous leukemia (AML)

a form of leukemia where immature lymphocytes (lymphoblasts) predominate

acute lymphocytic leukemia (ALL)

a form of leukemia where both mature and immature granulocytes are present in large numbers in the marrow and blood

chronic myelogenous leukemia (CML)

a form of leukemia where relatively mature lymphocytes predominate in the marrow, lymph nodes, and spleen

chronic lymphocytic leukemia (CLL)

disappearance of signs and symptoms

remission

when disease symptoms and signs reappear

relapse

abnormal increase in granulocytes in the blood

granulocytosis

an increase in eosinophilic granulocytes, seen in certain allergic reactions

eosinophilia

an increase in basophilic granulocytes seen in certain types of leukemia

basophilia

infectious disease marked by increased numbers of mononuclear leukocytes and enlarged cervical lymph nodes

mononucleosis

the virus that transmits mononucleosis

Epstein-Barr virus (EBV)

malignant neoplasm of bone marrow

multiple myeloma

an immunoglobin fragment found in urine that is overproduced in multiple myeloma

Bence Jones protein

relieving symptoms

palliative

a treatment for multiple myeloma where the patient serves as his/her own donor for stem cells

autologous bone marrow transplantation (ABMT)

test for the presence of antibodies that coat and damage erythrocytes

antiglobulin test (Coombs test)

time required for blood to stop flowing from a tiny puncture wound

bleeding time

time required for venous blood to clot in a test tube

coagulation time

determination of numbers of blood cells, hemoglobin concentration, hematocrit, and red cell values

complete blood count (CBC)

speed at which erythrocytes settle out of plasma

erythrocyte sedimentation rate (ESR)

percentage of erythrocytes in a volume of blood

hematocrit (Hct)

total amount of hemoglobin in a sample of peripheral blood

hemoglobin test

number of platelets per cubic millimeter or microliter of blood

platelet count

test of the ability of blood to clot

prothrombin time (PT)

number of erythrocytes per cubic millimeter or microliter of blood

red blood cell count (RBC)

microscopic examination of stained blood smear to determine the shape of the individual red cells

red blood cell morphology

number of leukocytes per cubic millimeter or microliter of blood

white blood cell count (WBC)

percentages of different types of leukocytes in the blood

white blood cell differential

separation of blood into component parts and removal of a select portion from the blood

apheresis

when plasma is removed from the patient and fresh plasma is given

plasma exchange

whole blood or cells are taken from a donor and infused into a patient

blood transfusion

the collection and later reinfusion of a patient's own blood

autologous transfusion

a preparation of blood cells separated from liquid plasma and administered in severe anemia

packed cells

microscopic examination of a core of bone marrow removed with a needle

bone marrow biopsy

removal of bone marrow with a brief suction produced by a syringe

bone marrow aspiration

peripheral stem cells from a compatible donor are administered to a recipient

hematopoietic stem cell transplantation

a stem cell transplantation where the patient's own stem cells are collected, stored, and reinfused

autologous stem cell transplantation

a transplantation where a patient receives stem cells from a donor

allogeneic transplant