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22 Cards in this Set

  • Front
  • Back

Where does nociceptive pain arise from and what receptors does it activate?

damage to non-neural tissue activating pain receptors (nociceptors)



What is neuropathic pain caused by?

A lesion of the somatosensory nervous system

How might pain of unknown origin be enhanced?

CNS excitability or loss of central inhibition

By what pathway are pain and temperature sensations carried?

Via the spinothalamic

Where is the first order neuron cell body located?

the dorsal root ganglion

Where do the first order neurons enter the cord, travel, and then end?

Tract of Lissauer and ascends 1 to 3 levels before it ends in the substantial gelatinous of the dorsal horn

Where is the second order neuron cell boy located?

substantia gelatinosa

Where does the second order neuron start, travel and end?

Starts in the substantia gelatinous and crosses the contralateral side of the spinal cord in the anterior white commissure, and then enters the lateral spinothalamic tract.

Where does the lateral spinothalamic tract end?

Ascends the spinal cord and brainstem to the end in the ventral posterolateral nucleus of the thalamus. (VPL)

Where are the third order neuron cell bodies, travel, and then end?

in the VPL and then run superiorly through the posterior limb of the internal capsule to end in the post central gyrus of the cortex.

What is the area 3,1,2 of the post central gyrus called?

primary somatosensory cortex

Where will symptoms show up if the first order neuron is affected?

The ipsilateral side of the lesion

Why are the signs and symptoms of a first order neuron lesion found below the level of injury?

Because the first order neuron usually ascends the spinal cord before crossing over.

Why might sensations be felt bilaterally below the level of the lesion?

If the lesion involves the anterior white commissure because first order fibers from both sides of the body cross the spinal cord.

Where will the signs and symptoms show up if the second order neurons are affected?

on the contralateral side of the injury

What would the lesion of a second order lesionpresent with?

Contralaterally beginning a few levels below the level of the lesion.

Where would the signs and symptoms of a third order neuron be presented?

Contralaterally

What might lesions involving the thalamus produce?

thalamic syndrome

What do deep touch, proprioception, vibration, and two point discrimination involve?

dorsal columns of the spinal cord and the liminiscal system in the brainstem.

What are the neurons involved in the leminiscal system?

1) First order neurons


2) Second order neurons


3) Third order neurons

What is stereognosis?

the ability to determine three dimensional structure by using tactile sense

What is the name of the condition where the patient has tactile input, but is unable recognize objects placed in their hand without visual cues.

Astereognosis