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21 Cards in this Set
- Front
- Back
What causes antibiotic resistance |
overuse |
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why does overuse cause problems with antibiotic resistance |
mutations, selection, and conjugation |
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what are the causes of antibiotic resistance due to overuse |
over-prescribing, agriculture |
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Penicillin and Cephalosporin |
Cell wall breakers, |
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Penicillinase: |
weapon of the resistant microbe, enzyme that cuts penicillin |
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Vancomycin |
used in case of penicillin and methicillin resistance, or if PCN allergy, toxic and hard to administer, restricted use |
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isoniazid |
used for mycobacterium, anti TB |
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Polymixins |
cell membrane breakers, used topically |
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DNA gyrase |
enzyme that only prokaryotes have |
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Cipro |
breaks up DNA gyrase, quinolones |
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Ribosome toxins |
chloramphenicol, streptomycin, erythromycin, tetracycline, gentamycin |
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enzyme inhibitors |
sulfa drugs, mimic PABA, stop folic acid synthesis |
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-azoles |
antifungals, almost all are topicals because they are toxic |
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grisofulvin |
another type of antifungal |
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antiprotozoans |
chloroquine, metronidazole, flagyl |
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antihelminth |
vermox, niclosamide, pyrantel, piperazine |
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Amantadine |
antiviral, prevent fusion of virus with membrane |
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Relenza and Tamiflu |
influenza A & B, only works in first 36 hours of treatment |
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-cyclovirs |
anti-herpes |
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AZT/Azidothymidine |
retrovirus chemotherapy, interferes with viral DNA synthesis |
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Interferons |
human-based protein made by white blood cells |