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26 Cards in this Set
- Front
- Back
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What is the function of the lymphatic system? |
Has two functions 1. Immunity which is defined as the body’s ability to resist infection and disease. 2. Maintaining normal blood volume and composition of interstitial fluid |
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innate immunity types |
Includes: o Physical barriers—skin and mucous membranes o Phagocytes—cells that engulf pathogens and cell debris o Immune surveillance—destruction of abnormal cells by natural killer (NK) cells o Interferons—chemicals against viral infections o Complement—circulating proteins that assist antibodies o Inflammation—localized tissue-level response to limit spread of infection o Fever—elevation of body temperature |
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innate vs adaptive immunity? |
Innate : Nonspecific, rapid response Adaptive : high specific, slow initial response, memory response faster. |
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lymphoid organs vs nodules? |
Lymphoid nodules a. Densely packed lymphocytes in an area of areolar tissue b. Nodules may cluster together and form larger masses c. No fibrous capsule surrounds the masses Lymphoid organs a. Separated from surrounding tissues by fibrous connective tissue capsule |
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antigen vs antibody? |
An antigen is a molecule that stimulates an immune response whereas an antibody is a protein made in response to an antigen. |
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What is the structure of the spleen? |
The spleen is the largest lymphoid organ, responds to antigens in the bloodstream
Two types of pulp: o Red pulp Contains large quantities of RBCs Also contains macrophages o White pulp Resembles lymphoid nodules with lymphocytes |
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White pulp in the spleen is populated by |
Lymphocytes |
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Describe white and red pulp found in the spleen |
Red pulp contains large numbers of red blood cells; white pulp resembles lymphoid nodules and contains lymphocytes. |
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Connective tissue dominated by lymphocytes define |
Lymphatic tissue |
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Define osponization |
Coat pathogens and damaged cells, and bind to receptors on the surface of phagocytes, enhancing the ability of neutrophils, macrophages, and DCs to engulf material. |
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Adaptive Immunity is the result of the actions of |
Interferons are small proteins released by virus-infected cells that trigger the production of antiviral proteins. |
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Immunity that is genetically determined, and present at birth is called ? immunity |
Innate immunity |
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The cells that perform immunological surveillance is |
NK cells |
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B cells are primarily activated by the activities of |
Helper T Cells |
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Define immune surveillance |
the constant monitoring of normal tissues by NK cells sensitive to abnormal antigens on the surfaces of cells. |
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Identify 3 major T-cells activated by class 1MHC proteins |
cytotoxic T cells, memory Tc cells and suppressor T cells. |
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The primary function of the lymphatic system substance that provoke |
The production, maintenance and distribution of blood cells, called lymphocytes |
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Substance that provoked a immune response what is a perf |
Antigen |
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What is perforin |
a protein found in cytotoxic t cell (and NK) granules which creates pore-like lesions in the membranes of targeted cells, |
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Describe inflammation |
A localized response to injury, categorized by redness, swelling, heat and pain |
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Lymphocyte production does not occur in |
The liver |
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T cells is to as B cells is to |
thymus dependent; bone marrow-derived |
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What is the difference between an lymphocyte and a lymph |
Lymphocyte is the primary cell of the lymphatic system. Lymph is interstitial fluid that has entered a lymphatic vessel |
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The body’s nonspecific defenses include except |
Antibodies |
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after puberty the thymus gradually shrinks and becomes more fibrous in a process called |
Involution |
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All of the following is true for lymphocytes except |
they are granulocytes. |
