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264 Cards in this Set

  • Front
  • Back

Continuous proliferation of new segments or proglottids

Strobila grows throughout the life of a tapeworm by _____

New segments

Referred to as immature


Do not contain gully developed internal structures

Mature proglottids

Are larger and found near the middle of the chain


Contain one or two sets of male and female reproductive organs

Gravid proglottids

Terminal portain of the strobila


Contain the eggs

Uterus

Eggs are enclosed in____.


A structure that varies in size and shape in different cestode species

Small intestine

Adults inhabit the____

Scolex

Attachement is accomplished by means of_____

Four muscular, cup-shaped suckers

All human cestodes have ______ on the scolex

Rostellum

Elongate and protusible structures situated in the center of the scolex

Armed

Rostellum bears hook referred to as ____

Host's intestine

No digestive system, food is absorbed from the _____

Eggs or proglottids, scolex

Precise identification of tapeworm of human is based on _____

Diphyllobothrium latum


Taenia saginata


Hymenolepis diminuta

Human as definitive host only

Taenia solium


Hymenolepis nana

Human as intermediate or definitive host

Echinococcus spp.

Utilize human as intermediate host but never a definitive host

Anoncosphere

Bears six elongate hooks and serves as protective coverings of the embryo

False

Infection cause by adult worm is much more serious that the extraintestinal infection cause by larval forms


(T/F)

Taenia saginata

Beef tapeworm

Taenia solium

Pork tapeworm

Ingestion of larvae in beef or pork

Means of human infection (taeniasis)

Muscle, brain, eye

Location of larvae in humans ( T. solium)

Not present

Location of larvae in humans


( T. saginata)

Small intestine

Location of adult worms in human


(taenia spp)

Vague digestive disturbances, anorexia, majority asymptomatic

Clinical features of taeniasis

Embryonated eggs or proglottids in stool

Laboratory diagnosis of taeniasis

Upper jejunum

Adult of t. saginata inhibit the _____ for up to 25 years

Adult of T. saginata

measures 4 to 10 m in length and may have 1,000 to 4,000 proglottids


Adult of T. saginata

cuboidal scolex with four prominent acetabula or suckers

Adult of T.saginata

devoid of hooks or a rostellum

Adult of T. saginata

with short neck from which a chain of immature, mature, and gravid proglottids develop

Adult of T. saginata

hermaphroditic

Mature proglottids (T. saginata)

wider than long or approximately square in shape


Mature proglottids (T. saginata)

two large lobes of ovaries and a median club-shaped uterus

Mature proglottids (T. saginata)

follicular testes numbering 300 to 400 are scattered throughout the proglottid


vagina has sphincter

Gravid proglottids ( T.saginata)

longer than they are wide

Gravid proglottids (T. saginata)

has 15 to 20 lateral branches

Gravid proglottids (T. saginata)

undergo apolysis and are either passed out of the feces or actively crawl out of the bowel

Eggs ( T. saginata)

spherical or subspherical in shape measuring 30 to 45 um in diameter

Eggs ( T. saginata)

brownish in color with a thick embryophore which appears striated because of numerous pits

Eggs ( T. saginata)

inside the eggshell is the oncosphere or embryo provided with three pairs of hooklets

identification of characteristic proglottids, eggs, or scolex

Diagnosis of T. saginata

Praziquantel

Treatment for T.saginata

Small intestine

Adult of T. saginata inhabit the _____

Adult of T. solium

measures 2 to 4 m in length and may have 800 to 1,000 proglottids

Adult of T. solium

scolex has four acetabula and a cushion-like rostellum with a double crown of 25 to 30 large and small hooks

Mature proglottids

wider than long; morphology resembles that of T. saginata

Mature proglottids

presence of accessory ovarian lobe and absence of vaginal sphincter

Gravid proglottids (T. solium)

longer than wide contains 7 to 13 lateral branches

Gravid proglottids ( T. saginata)

undergo apolysis and relatively less active (not observed to actively crawl)

Praziquantel and niclosamide

Treatment for T.saginata

Cysticercosis

Infection with the larval form of Taenia solium, T. saginata, T. crassiceps, T. ovis, T. taeniaeformis or T. hydatigena is called cysticercosis.

Cysticerci

Bladder worm


Larvae of Taenia solium, T. saginata, T. crassiceps, T. ovis, T. taeniaeformis or T. hydatigena

Cysticercus cellulosae

bladder worm of T. solium was known as


Ingestion of eggs

Means of human infection (cysticercosis)

Neurocysticercosis

Most serious manifestation of cysticercus cellulosae

Calcification

End result of cellular reaction

Cysticercus cellulosae

clinical features : asymptomatic to Jacksonian seizures, hydrocephalus, visual problems

Cysticercus cellulosae

laboratory diagnosis : X-ray, CT, MRI, serologic tests


Praziquantel or albendazole; surgical removal of the cyst


Treatment for cysticercus cellulosae

Proglottids, strobila

Chain of segments______ ,


also known as____

Multiceps multiceps

adult of moderate size is found in dogs and other Canidae

Multiceps multiceps

Cause coenerus disease

Coenurus

Larval stage of multiceps multiceps, occurs in herbivorous animals and occasionally in humans

dogs and other canidae

adult of multiceps multiceps is found in

staggers

cyst of multiceps multiceps develop in brain and spina cord causing a disease called _____ which affects the balancing power of animals

coenurus

larval tapeworms occur in large groups within a single cyst known as a

hymenolepis nana

 dwarf tapeworm; smallest tapeworm

hymenolepis nana

common parasite of house mouse

hymenolepis nana

 the only human tapeworm which can complete its entire life cycle in a single host (does not require an obligatory intermediate host)

ileum

adults of h. nana

adults of h.nana

 subglobular scolex with four cup-shaped suckers

adults of h. nana

 retractable rostellum armed with a single row of 20 to 30 Y-shaped hooklets

adults of h.nana

 anterior proglottids are short and the posterior ones are broader than long

mature proglottids (h.nana)

three ovoid testes and one ovary in a more or less straight pattern across the segment

eggs of h.nana

 spherical or subspherical measuring 30 to 47 um in diamet

eggs of h.nana

 six-hooked (hexacanth) oncosphere has a thin outer membrane and a thick inner membrane with conspicuous

eggs of h. nana

 immediately infective when passed with the stool and cannot survive more than 10 days in the external environment

hymenolepis nana

Arthropods, especially beetles, serve as intermediate hosts

False

The arthropod intermediate host is required for H.nana , but not H. diminuta


(T/F)

cysticercoids

Within the arthropod host, the eggs develop into _______, which can infect the mammalian host upon ingestion and develop into adults in the small intestine.

Tribolium confusum,

a common intermediate host for Hymenolepis spp.

tribolium and related genera


(h.nana)

breed in cereals, grains, and grain-based snack foods and are easily ingested by humans and rodents.

Hymenolepis nana

 enteritis, diarrhea, abdominal pain, anorexia  majority asymptomatic


eggs of hymenolepis nana

These eggs are oval and smaller than those of H. diminuta, with a size range of 30 to 50 µm.

 Praziquantel

treatment for h. nana

 personal hygiene and environmental sanitation  rodent control  proper storage of food  thorough treatment of cases


Prevention and Control for h.nana

Hymenolepis diminuta

common parasite of rat (rat tapeworm)

Hymenolepis diminuta

arthropod intermediate host (flour moths, flour beetles, fleas, cockroaches, mealworms, earwigs)

Hymenolepis diminuta

human infection through accidental ingestion intermediate hosts infesting dried grains, dried fruits, flour and cereals

Hymenolepis diminuta

scolex with a rudimentary unarmed rostellum

eggs of h. diminuta

 circular, about 60 to 80 um in diameter and are bile stained

eggs of h.diminuta

oncosphere is enclosed in an inner membrane, which has bipolar thickenings but lacks the bipolar filaments


(absence of polar filaments readily differentiates this species from H. nana)

 Praziquantel

treatment for h.diminuta

Dipylidium caninum

 common in cats and dogs; accidentally in humans especially children because of their close contact with their pets

Dipylidium caninum

 presence of actively motile proglottids in feces or underwear can be observed

Dipylidium caninum

requires an intermediate host (fleas and dog louse)

Dipylidium caninum

pale reddish, measures 10 to 70 cm in length

Dipylidium caninum

scolex is small and globular with four deeply cupped suckers and a protrusible rostellum which is armed with 1 to 7 rows of rose thorn shaped hooklets

Mature proglottids (D.caninum)

 narrow with two sets of male and female reproductive organs and bilateral genital pores (double-pored tapeworm)

Gravid proglottids (D. caninum)

size and shape of the pumpkin seed and are filled with capsules or packets of about 8 to 15 eggs enclosed in an embryonic membrane

eggs of D.caninum

spherical, thin-shelled with a hexacanth embryo

Dipylidium caninum

pets may exhibit behavior to relieve anal pruritis (such as scraping anal region across grass or carpeting

Praziquantel

Treatment for Dipylidium caninum

RAILLIETINA GARRISONI

 common tapeworm of rats

Raillietina garrisoni

 accidental infection on humans through ingestion of intermediate host found in stored grain products

Adult of R.garrisoni

 rostellum is armed with two alternating circular rows of 90 to 140 hammer-shaped hooks  several rows of spines also surround the rostellum


Mature proglottids of R.garrisoni

bilobed ovary surrounded by 36 to 50 ovoid testesgenital pore opens on the side near the anterior lateral border of the segment


Gravid proglottids of R. garrisoni

 about 2 mm in length containing 200 to 400 egg capsules with 1 to 4 spindle-shaped eggs

gravid proglottids of R.garrisoni

 motile, white, and appear like grains of rice in the feces

Gravid proglottids of R.garrisoni

 may be ingested by the intermediate host (flour beetle, Tribolium confusum)

eggs of R.garrisoni

 one to four spindle-shaped eggs in 1 egg capsule  oncosphere is enclosed in two thin membranes: an outer elongated membrane and an inner spherical membrane


eggs of R.garrisoni

 one to four spindle-shaped eggs in 1 egg capsule  oncosphere is enclosed in two thin membranes: an outer elongated membrane and an inner spherical membrane


 Praziquantel  sometimes complete expulsion of the worm without treatment

treatment for R.garrisoni

Diphyllobothrium latum

fish tapeworm or the broad tapeworm

adult of D.latum

 3 to 10 m in length and may have 4,000 proglottids  scolex is spatulate and measures 2 to 3 mm in length by 1 mm in diameter

adult of Diphyllobothrium latum

 has two bothria or sucking grooves which are located dorsally and ventrally  neck is long and attenuated

Gravid proglottids of D.latum

 dark, rosette-like, coiled uterus

eggs of D.latum

unembryonated when laid (approximately 1,000,000 per day); will complete development in water

eggs of D.latum

 yellowish brown, with a moderately thick shell and an inconspicuous operculum (the lid or caplike cover on certain platyhelminth eggs)

sparganosis

The condition in which plerocercoids or spargana develop in the definitive host is known as

D.latum

 can cause vitamin B12 deficiency anemia (cyanocobalamin)

fish-eating mammal

the larvae of D latum is ingested by

Praziquantel

treatment for D. latum

D.latum

thorough cooking of freshwater fish or freezing for 24 to 48 hours at -18 ℃;


marinating will not


personal hygiene and environmental sanitation


Human echinococcosis (hydatidosis or hydatid disease)

caused by the larval stages of cestodes (tapeworms) of the genus Echinococcus.


caused by the larval stages of cestodes (tapeworms) of the genus Echinococcus.

echinococcus granulosus

causes cystic echinococcosis, the form most frequently encountered

Echinococcus multicularis

causes alveolar echinococcosis

Echinococcus oligarthus

extremely rare cause of human echinococcosis

E. vogeli

causes polycystic echinococcosis

Echinococcus granulosus

hydatid tapeworm

Echinococcus granolosus

human accidentally ingests eggs by close contact with infected dog; usual intermediate host is sheep

Adult of E. granulosus

 pyriform scolex, short neck, and three proglottids (immature, mature, gravid)  scolex is taeniid in that it has four acetabula  armed with 30 to 36 hooks


Gravid proglottid of E. granulosus

widest and longest proglottiduterus is midline with lateral evaginations and is filled with eggs which resemble those of other taeniid worms


Dogs and canids

definitive host for Echinococcus spp.

Echinoccocus spp

eggs are not expected to be found in human stool and are not considered diagnostic in human infections.

Hydatid cyst (Echinococcus spp)

larval stage in the intermediate host (goat, horse, camel, sheep, human)

hydatid cyst (Echinoccocus spp)

unilocular


has an outer laminated hyaline layer and an inner nucleated germinal layer

Hydatid Sand

 granular material consisting of free scolices, hooklets, daughter cysts, and amorphous material  found in the fluid of older cysts of E. granulosus

serious anaphylaxis

may result from large amount of hydatid material entering the bloodstream when primary cyst ruptures

serious anaphylaxis

may result from large amount of hydatid material entering the bloodstream when primary cyst ruptures

diagnosis of Echinococcus granulosus

 X-ray, ultrasound, CT  aspirate of “hydatid sand”  serologic tests


Surgical resection (treatment of choice)  Albendazole for inoperable cysts


Treatment for E. granulosus

E.multicularis

 foxes are the natural definitive host, and to a lesser extent dogs, cats, coyotes and wolves; the intermediate host are small rodents

liver

 most common site of alveolar hydatid cyst ( E. multicularis) is the

surgery or albendazole

treatment for E.multicularis

E.vogeli

 definitive hosts are bush dogs and dogs; the intermediate hosts are rodents

Echinoccocus oligarthus

 has a life cycle that involves wild felids as definitive hosts and rodents as intermediate hosts

Sparganosis

infection by the plerocercoid larvae of various diphyllobothroid tapeworms belonging to the genus Spirometra

Sparganosis

infection by the third-stage plerocercoid larva (sparganum) of pseudophyllidean cestodes of the genera Spirometra.

Species of Spirometra

S. mansoni, S. mansonoides, S. erinacei, S. ranarum, S. decipiens, S. houghtoni, S. proliferum .


Ocular sparganosis

may result in blindness

Cerebral sparganosis

characterized by seizures, fatigue, fever, confusion, headaches, memory loss, and other CNS symptoms

 Proliferative sparganosis

caused by S. proliferum, begins with a subcutaneous tumor in the thigh, shoulder, or neck, and eventually spreads to other parts of the body

Sparganum proliferum

multiple skin lesions which are mostly papular and nodular.

1. drinking water contaminated with copepods infected with the procercoid larval stage of the parasite 2. ingestion of undercooked meat, such as pork, that is infected with the plerocercoids 3. placing poultices of frog or snake flesh on open wounds or other lesions, or the eyes

3 major routes of Spargamum infection

Spargamum proliferum

Dogs and cats are the primary hosts of the adult worm.

Spargamum proliferum

The first intermediate hosts are copepods, or freshwater crustaceans. The second intermediate hosts are amphibians, reptiles, birds, and mammals

humans

serve as paratenic or second intermediate hosts and develop sparganosis.

Snakes and tadpoles/frogs

vectors for sparganum.

Surgical removal and Praziquantel

Management and Therapy for Sparganosis

MRI, CT, ELISA

Diagnostic test for Sparganosis

adult cestodes

Flat and ribbon-like

White or yellowish

Color of cestodes (living worms)

Scolex

Anterior attachment organ

1. drinking boiled or filtered water 2. cooking possible intermediate and paratenic hosts thoroughly 3. avoiding the practice of applying flesh of frogs to inflamed areas

Prevention for Sparganosis

Platyhelminthes or flatworms

dorso-ventrally flattened with bilateral symmetry

Cestodes

segmented, ribbonlike appearance

trematodes

unsegmented,like

Cestodes , trematodes

do not have a digestive tract


while __ has incomplete one.

scolex

main organ of attachment of the worm to the definitive host

neck

the region of growth, because segmentation or strobilization originates from it.

immature, mature , gravid

Segments or proglottids that are nearest to the neck are the most ____ , followed by ____ , and the most distal are _____ segments

Cyclophyllidea and Pseudophyllidia

Two orders of tapeworms with medical and public health significance

Pseudophyllidea

have a spatulate scolex with sucking grooves called bothria

Cyclophyllidea

scolex is globular with four muscular suckers

Pseudophyllidea

segments have uterine poor which allows release of eggs from the gravid uterus

Cyclophyllidea

do not have the uterine pore , undergo the process of apolysis

apolysis

segments are detached from the main body of the worm and eggs are eventually released

Non-operculated cyclophyllidea eggs

are passed out readily, containing the hexacanth embryo

Pseudophyllidea, coracidium

eggs are operculated and immature ,require aquatic development of the embryo, called the _____

Procercoid larvae-1st intermediate


plerocercoid larvae-2nd

Two intermediate host of Pseudophyllidean worms

Diphyllobothrium

a Pseudophyllidean worm which utilizes human as definitive host

Spirometra

a Psedophyllidean worm which utilizes humans as intermediate host

Diphyllobothrium and Spirometra

two worms that belong to order Pseudophylidea

Cyclophyllidea

order that require only one intermediate host

cysticercus type

encysted larvae of Taenia in intermediate host

Hymenolepis, Dipylidium, Reillietina

produce the cysticercoid tyoe

Echinoccocus spp.

hydatid is produced by

cysticercus

humans are infected with the larval stage of Taenia spp. called

Cysticercus bovis

infective stage of T.saginata


cysticercus is ovoidal, milky, white

oncosphere or embryo

provided with three pairs of hooklets

Taenia saginata gravid segments

Taenia egg

life cycle of Taenia spp.

indian ink

injection to the genital pore will make an accurate count of the lateral branches of the uterus (15-20 T. saginata) (7-13 T. solium/

T. saginata


T.solium

vagina sphincter is to___


accesory ovarian is to ____

Formalin-ether /ethyl acetate concentration technique

enhance the chance of demontrating the eggs

Recovery of the scolex


negative stool examination 3 months after treatment

Criteria for cure

upper small intestine

in Taenia saginata, adult worm inhabits the

T.solium

thick brown striated embrophore surrounding the hexacanth embryo

Measly pork

Infective meat is often called

Parenchymal and extraparemchymal


subarachnoid of meningitic form


intraventricular


spinal

two general form of neurocysticercosis,


further divided into

racemous cysticercosis

the subarachnoid form may lead to aggresive form of neurocysticercosis called

Intraventricular form

in this form, cyst are usually present in the third or fourth ventricle and often lethal leading to obstructive hydrocephalus.

subarachnoid form

in this form, there is a proliferationcyst in the base of the brain

neurocysticercosis

subcutaneous cysticerci cocomitant withneurologic symptoms

Dot-ELISA TEST

very good screening test for cysticercosis

high doese corticosteroid therapy and mannitol)

parenchymal forms presenting a cysticercotic encephalitis or those with massive parasitic infection (treatment)

surgical removal or albendazole therapy

treatment fr subarachnoid form

surgical removal or albendazole therapy

treatment fr subarachnoid form

surgical removal of the cysts

treatment for ventricular forms

praziquanteln or abendazole

treatmemt for ocular cysticercosis

Taenia asiatica

cysticercus larvae were found in the liver of various intermediate host yhat include pigs, cattle , giat, wild boars and monkeys

cysticercus viscerotropica

cysticercus larvae of Taenia asiatica

cyticercus viscerotropica

cysticercus witha wart-loke protuberances on the external surface and contains an invaginated scolex armed with vestigial hooklets

Taenia asiatica

the gravid proglottids have posterior protuberance with 11 to 32 lateral branches

Taenia asiatica

Freezing at -20degrees C. for 10days kills the cysticerci

Hymenolepis nana

no more than 175 to 220 segments composed the entire length of strobila

Hymenolepis nana

Mature proglottids contain three ovoid testes and one ovary in a more or less straight patterbaccross the segments

Hymenolepis nana

eggs are spherical or subspherical, colorless or clay-colored

H. nana

the oncosphere has a thin, outer membrane with conspicuous bipolar thickenings, from each of whixh arise four to eight hair-ioe filaments embedded in the inner membrane

H.nana

a heavy infections may result in enteritis due to necrosis and desquamation.

H.nana

Human tapeworm found among mice and less frequently among rats

H.nana var. fraterna

the species in mats and rats is considered to be a distinct subspecies

Hymenolepis nana egg

Hymenolepis diminuta

the hooklets usually have fan-like arrangement

H. diminuta

eggs when ingested by a wide range of adult and larval insects like fleas, betetles, cockroaches,mealworms, earwigs develop into infective cysticercoid larvae

H. diminuta

larger size, more circular shape than H.nana and lack of bipolar filaments

Dipyllidium caninum egg capsule

Dog flea (D. caninum)

Ctenocephalides canis as intermediate host

cat flea (D. caninum)

Ctenocephalides felis as intermediate host

human flea ( D. caninum)

Pulex irritans as intermediate host

Dog louse ( D.caninum)

Trichodectes canis as intermediate h

Raillietina garrisoni

belongs to the famiy Davaineidae

Raillietina madagacariensis

first reported by Garrison to be present in an adult Filipino

R. garrisoni

the segments are motile, white, appear like grains of rice

R. garrisoni

flour beetle (Tribolium confusum ) as intermediate host

Raillietina garrison

common intestinal cestode of rodents in the Philippines

Diphyllobothrium latum

broad tapeworm or fish tapeworm

D.latum

two bothria or sucking grooves located ventralky and dorsally

D.latum

dark, rosette-like, coiled uterus

D.latum

opposite the operculum is a smal knob-liie thickening

D.latum egg

copepods

procercoid larvae of D.latum develop in ___

plerocercoid larva or sparganum

measures 20mm or more and appear glistening, opaque, white and unsegmented

dog, cat and other animals

definitive host of D.latum

Canivorous fish

serve as paratenic or transport host of D.latum

-18 degrees celsius

Freezing for 24-48 hours at a temperature of _____ kils all the plerocercoid

Echinococcus spp.

belongs to the Family Taeniidae, order Cyclophyllidea

Echinococcus spp.

the scolex is armed with 30 to 36 hooks

Exhinoccocus spp.

intermediate hist are goat, camel, sheep and horse

Liver

the most common and most important site of Echinococcus spp.

unilocular hydatid cyst

the cyst of E. granulosus is called

alveolar cyst

the cyst of E. multicularis is called

hepatic cyst

cyst that are mostoy found in the inferior rightnlobe , and may present as haoatic enlargement, right epigastric pain or jaundice

Type CL


CE1


CE2


CE3


CE4


CE5

Classification of Hepatic Echinococcal cyst

PAIR technique


(percutaneous apiration, injection, reaspiration)

indicated for patients with single or multiple cyst in the liver, abdomina cavity, spleen ,kidney or bones

Spirometra mansoni, S. erinacei, S. ranarum

commonly involved in human sparganosis

Spirometra spp.

intesrinal parasites of cats, dogs and oter carnivores

Spirometra spp.

gravid proglottids have spira uterus

Spirometra spp.

gravid proglottids have spira uterus

fish, snakes, chicken

second intermediate host of Spirometra spp containing plerocercoid larvae

D.latum

ova are usually yellowish brown with a moderately thick shell and inconpicuous operculum

Cyclops

first intermediate host of Spirometra spp infected with procercoid larvae