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18 Cards in this Set

  • Front
  • Back
Centrosome
Attached to outside of the nucleus.

Made up of 2 centrioles.
Astral fibres
Extend from cenromere.

Does not connect with other structures.
Pole to Pole fibres
Connects centrioles.
Kinetocore fibres
Connects centriole to kinetocore proteins which bind chromosomes.
Metaphase Plate
Mid point between centrosomes.

Chromosomes meet here durin metaphase.
Dynesin
Breaks down microtubule between the kinetocore and (forming) metaphase plate.

This allows the chromosomes to move towards the metaphase plate.
Kinesin
Creates microtubules on the side of the kinetocore closest to the centrosome.

Replaces microtubule broken down by dysein.
Cohesin
Holds sister chromotids together.
Seperase
A protease that breaks down cohesin.

Keped inactive until late metaphase.
Securin
A chaperone protein.

Keeps seperase inactive
Anaphase Promoting Complex (APC)
Breaks down securin allowing seperase to activate.

Controlled by CDKs.
Cytokinesis
Cell division.
Actin fillaments
Assemble under plasma membrane to form a ring around the metaphase plate.
Myosin II
A non-muscle myosin.

Induces contraction of actin ring by causing fillaments to slide over each other.
MLC kinase
Regulates Myosin function when activated.
ROCK
Regulates MLC kinase
Cleavage Furrow
Furrow in membrane created by contraction of actin ring.
Cytoplasmic vesicles
Promotes cell fission by delivering plasma membrane.