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338 Cards in this Set

  • Front
  • Back

BreastCheck

50-69. Every 2 years

Who to refer with breast cancee

- first degree female relative diagnosed less than 40


- first degree male relative diagnosed at any age


- first degree relative with bilateral breast cancer diagnosed less than 50


- 2 first degree relatives at any age


- 1 first and 1 second degree relative at any age


- 1 first/second degree relative with breast and 1 with ovarian at any age

Cervical check

25-44 - 3 yearly


45-60 - 5 yearly

Levo

72 hours (3 days)


Vomit less than 2 hours

EllaOne

120 hours (5 days)


Vomit -3 hours


HTN drugs

1) amlodipine 5mg OD (5-10mg) - side effect is ankle swelling


2) bendroflumethiazide 2.5mg


3) ramiprol 2.5mg - dry cough, lightheadedness, renal impairment



Check kidneys after 2 weeks.


Check bp after 4 weeks.

Warning with csrbimazole

If they get a sore throat or feel unwell. Stop tablet and come and get FBC.

Tonsils

Paradise Criteria



-impacting in school attendance


- 7 or more n past year, 5 or more in each past two years and 3, or more in each past 3 years


- sleep apnoea


- 2+ episodes of quinsy

BPH meds

1) alpha blockers. Eg tamsulosin 0.4mg OD. Relax bladder muscles



2) 5 alpha reductase inhibitors eg finasteride 1mg OD. Anti androgen. Shrink prostate

Target hBA1c

7 . 53


6.5 (48)

Things to avoid headaches

Stress, chocolate, cheese, alcohol, missed meals, sleep, cocp.

Headache red flag

1) Raised ICP: headache on walking, coughing, sneezing


2) thunderclap headache


DVT exam

- measure the calf circumference 10cm below the tibial tuberosity


- look for more than 3 cm difference in calf circumference

What to avoid with contact dermatitis

Aqueous cream and E45- these contain lanolin and sodium lauryl sulphate which can irritate the skin further.

Down Syndrome risk

25: 1 in 1200


30: 1 in 800


35: 1 in 350


40: 1 in 100


45: 1 in 50


Risk of CVS

1%

Exam in Erectyle Dysfunction

1) CVD


2) Hypogonadism: testiculsr size and body hair


3) Anatomical : Peyronie's, phimosis


4) Prostate exam

What to tell PT on Viagra

Advise them to attend ED if it lasts more than 4 hours

Shingles treatment

800mg five times a day X 7 days


Within 72 hours

Common is acne?

5 in 100 suffer with it every year

SSRI drug of choice for anxiety

Sertraline

Causes of falsely high BNP

Anaemia, renal failure, age, liver disease, sepsis

Diabetes dx

Symptomatic and rbg 11.1



Asymptomatic:


- fbg 7 (repeat)


- OGTT 11.1


- hBA1c 48

IGT

OGTT 7.8-11.1


Hba1c target in diabetics

53 (7.0)


58 (8.0) if elderly or having lots of hypos


48 (6.5) if very young!!!

Diet advice for diabetics

- Reduce saturated fat, trans fat and cholesterol intake



- Increase omega 3, fibre

Metformin MOA

Decreases hepatic gluconeogenesis and increases insulin sensitivity

Sulphonylurea MOA

Stimulates insulin secretion

DPP4 MOA

Increases insulin secretion

MOA SGLT2

Reduces glucose reabsorption therefore increasing renal glucose excretion

DM management (Medication)

1) Metformin 500mg BD. Titrate to 1g BD if still above 53!



2) if still above 53. Add



Sitagliptin, a DPP4 . Aka janumet



If over weight add either SGLT, Forxiga or gLP1 victoza

How much exercise in diabetes

150 minutes a week over at least 3 days. Or 90 minutes vigorous exercise. No more than 2 days between each session. Try to break up amounts of time spent sitting

Orlistat

Recommended if


1) BMI more than 30


2) BMI more than 28 with significant comorbidities



X3 months then we weigh. Only continue if weigh loss more than 5%>.




MOA: works by blocking chemicals in your gut which digest fat. Nearly a third of the fat that you ear is blocked by orlistst. Therefore the undigested fat is not absorbed into your body and is passed out with ur stools.



Drugs that can cause hyperthyroidism

1) Amiodarone


2) Lithium

Risk with carbimazole

Agranulocytosis, aplastic anaemia, hepatitis. So NB to check FBC and LFT

Effectiveness of statin

Reduce risk by 25% over a ten year period

Raynaud's meds

Nifedipine 5mg TDS

Tx for CCF

1) diuretic (symptom control only)



With either:



- ace first (if diabetic) if EF less than 40%


- beta blocker first (if angina)



Then add in other drug.

Role ace

Improves LV function and prognosis

Role beta blockers in ccf

Improves exercise tolerance, ejection fraction and prognosis

NICE statin targete

Total less than 4


LDL less than 2

Mg PVD

Risk factor mg:


1)aspirin switch to clopidogrel


2) weight loss


3) smoking cessation


4) BP review


5) cholesterol




Ischaemic mg:


Exercise therapy. 5x 30 minute episodee

ABI results

1) normal greater than or equal to 1


2) intermittent claudication 0.5- 0.9 3) critical limb ischaemia less than 0.5

Starting dose amlodipine and side effects

5mg. Ankle swelling

Starting dose ACE and side effects

RAMIPRIL 1.25MG. DRY COUGH, LIGHT- HEADEDNESS, RENAL IMPAIRMENT

BP Targets


140/90 or more. Repeat. If different repeat again. Record the lower of the last two. If higher get ABPM (135/85)




Less than 140/90 In those under 80


Less than 150/90 in those over 80


Less than 140/80 if diabetic


Less than 130/70 if microalbuminuria

Meningitis prophylaxis for contacts

Rifampicin no longer used.


Ciprofloxacin is used in all including those pregnant;



Adults and children over 12: 500mg stat


Children 5-12: 250mg stat



-prolonged close contact eg living together during 7 days before onset of illness


- transient close contact ONLY if they have been directly exposed to droplets/secretions from respiratory tract



Risk of getting meningitis in schiol

Pre school 1/1500


Primary: 1/18000


Secondary: 1/33000

Meningitis red flags

Confusion


Photophobia


Rash


Neck pain/stiffnees

When to refer mouth ulcers/ white patches

White patches if painful/bleeding/swollen



Or if persisting more than 3 wreks

When to refer hoarseness

More than 3 weeks!!!

Bells palsy

LMN. So forehead is affected.

Tx Bells Palsy

1) if within 3 days. Prediction 25mg BD for ten days has been shown to improve chance of full recovery



2) no antiviral meds (unless rash/vesicles)



3) lubricating eye drops and taping eye closed at night if they can't close it

IBS diagnose

Recurrent ab pain or discomfort at least 3 days a month in the last 3 months with:



-improvement with defecation


- change in frequency of stool


- change in appearance of stool

Explain two types of Fybogels

1) Anti-spasmotic: Fybogel mebeverine



2) Bulk-laxative: Fybogel Ispaghula

Mother to baby risk of hep C transmission

6%

Hep C facts

25% clear it, 75% develop a chronic infection. Of these 80% go onto develop hepatitis which puts them at increased risk of HCC or liver failure

Ankle capsular pattern

1) ankle. Dorsiflexion more than plantar flexion


2) Sub-talar: equal limitation of inversion and eversion


3) mid tarsal: limited adduction and medial rotstion

Toe and heel walking

Toe walking: L5/S1


Heel walking: L4

Special test in lumbar spine

Slump, straight leg raising

Capsular pattern at hip

Internal rotation more than flexion more than abduction

Causes of haemarthrosis

ACL


Patellar dislocation


Tibial condyle fracture


Rarely- peripheral meniscal tear

Gout uric acid levels

Aim to treat until levels less then 300mcg.

Gout treatment doses

Colchicine 500mcg BD to QDS


Naproxen 750mg stat then 250mg TDS

Failure rate of vasectomy

1: 2,000

Riska of tubal ligation

1: 200



More complications

Causes of gynaecomastia

1) physiological- puberty and older men


2) cancers


3) hyperthyroidism


4) obesity


5) medications:


- alcohol, steroids


- testosterone inhibitors eg finasteride, PPIs


- increase prolactin: eh antipsychotics, TCA


- testosterone production inhibitors: metronidazole, spironolactone


Causes of premature ejaculation

1) anxiety


2) drugs eg cocaine


3) MS


4) erectile dysfunction


5) medicines

Med for premature ejaculation

SSRI Dapoxetine. Much faster acting than usual SSRI.

Preventors for migraines

1) Topiramate 25mg, titrated up weekly (risk of fetal abnormalities)



2) propranolol 80mg.

Red flags of migraine

1) Fever


2) trauma


3) thunderclap headache


3) raised ICP (headache on waking, coughing, sneezing)


4) SOL ( postural, early morning, vomiting)

Things not to do before PSA

1) active urinary infection


2) ejaculated in previous 48 hours


3) prostate biopsy in previous 6 weeks

Prostate cancer fact

Leading cause of cancer in men



1/4 of men with raised PSA will have cancer on subsequent biopsy



Only 1 in 8 screening detected cancers are likely to cause death if left untreated!!!!!

Who should get screened???

1) 50-70 years.


2) 45 years if first degree relative with prostate cancer or if you are Afro Carribean

PSA normal levels

Less than 50: less than 2


50-59: less than 3


60-69: less than 4


70+: less than 5

ADHD treatment

Behavioural therapy


Family therapy


Sometimes medications

Criteria for ADHD

1) onset before 12 years


2) must occur in more than one settling


3) affect their ability to function socially and academically


4) inattention


5) hyperactive

How common are migraines

1 in 4 women


1 in 12 men

Red flags with constipation

1) from birth


2) ribbon stools


3) meconium passed more than 48 hours of birth


4) FTT


5) vomiting

Autism features

1) Social interaction


2) Communication


3) No imaginative play

How common is colic?

3 out of every 10 babies


- usually goes away by the age of 3-4 months, at the latest 6 months

Growth per year

4-8 cm per year from age 3


Then at puberty they grow 8-10cm per year

HPV side effects

1)1 in 10: erythema, pain/swelling in injection site, headache


2) 1 in 100: nausea, mild fever, pain in arm


3) 1 in 1000/10,000: urticaria


4) 1 in a million: severe allergic reaction

When to investigate delayed puberty

1) no puberty signs in girl aged 13


2) boy aged 14

CI for EllaOne?

Breastfeeding or asthma

Treatment of genital herpes

Aciclovir 200mg five times a day for five days (start within five days of lesions)

Contraception and age

Coco: stop age 50


Pop: stop age 55


Depo: stop age 50


Implanon: stop age 55


Copper: if inserted over 40 years can be kept in until or has gone through menopause


Mirena: if inserted at 45 it can be kept in


Increased breast cancer risk

From 30 in 10,000 to 38 in 10,000

HRT options

1) cyclical: femoston 1/10mg OD



2) continuous with uterus: femoston conti 0.5mg OD



3) continuous with no uterus: femotab 1mg OD

Med to treat urge incontinence and side-effects

Oxybutynin.



Dry mouth + constipation

Treatment if risk of PET

Aspirin 75 after week 12:




- more than 10 years since last pregnant


- over 40 or BMI more than 35 at presentation


- first preg- more than 10 years since last pregnant- over 40 or BMI more than 35 at presentation- previous PET- FH (first degree)- diabetes/HTN, renal disease


preg- more than 10 years since last pregnant- over 40 or BMI more than 35 at presentation- previous PET- FH (first degree)- diabetes/HTN, renal disease


- previous PET


)


- FH (first degree)- diabetes/HTN, renal disease


- diabetes/HTN, renal disease

Infertility stats

With 100 healthy couples who try to conceive naturally, 84% will succeed in one year, 92% will succeed in 2 years



In 1/4 cases a specific case is not found.

Frequency of menopause symptoms

8 in 10: vasomotor symptoms. Usually last around 2-5 years but can last up to 10 years



30%: vaginal symptoms (dryness, itching, dyspareunia)

Ponston dose

500mg TDS

Transexamic acid dose

1g TDS

Buproprion CI (Xyban)

- seizure disorders


- eating disorders (due to higher risk of seizure)


- MAO-i

E cigarette safety profile

95% safer than cigarettes as per Bmj article in Feb/March time

Stage COPD

1) stage 1= FEV1 more than 80%


2) 50-79 = stage 2


3) 30-49 = stage 3


4) less than 30 = stage 4

Gout risk factors

Alcohol


Purines (red meat, seafood)


Drugs that raise plasma urate levels: aspirin, diuretics, ciclosporim


FH


Kidney disease

Allopurinol

Starting dose 100mg


Titrate until serum acid level is below 300mcg


Prescribe colchicine also to prevent acute attack (for 3 months) or NSAID for 6 weeks with PPI.

Concussion symptoms

C: onfusion


H: headache


I: mbalance


P: ersonality



Causes functional disturbances rather than structural injury to brain, so standard imaging typically does not detect anything

Concussion recovery

80-80% resolve in 7-10 days!


Staged rehab!

Concussion recovery times

23 days- Irish rugby football union.


At least 24 hours at each stage


1) no activity


2) light aerobics


3) sport specific exercise


4) non contact drinks.5) full contact


5) return to play

Medication for weight loss

Orlistst. If BMI more than 30.



3 month trial


Side effects are an cramps, fatty stools, anal leakage

Thrush in pregnancy

Treat only if symptomatic


Top pessaries for 7 days!

Chronic pain treatment

1) Acupuncture


2) Exercise therapy (good for elderly)


3) Self help books. Everything Arthritis UK Chronic Pain Guide for patients


4) Refer to pain management programme


5) Progressive relaxation exercises- online

Chadsvasc

C: CF. 1


H: TN. 1


A: ge -75. 2


D: M. 1


S: troke/TIA/VTE. 2



V: ascular disease. 1


A: he 65-74. 1


S: ex; Female. 1




Do not treat if under 65 and chadsvasc 0 for men and 0 or 1 for women. Low risk!!!!!!



Women: 0/1 low risk. Do nothing


Men: 0 means no need for anti-coagulation

PPI

Preferred drug is lansoprazole 30mg OD X 1 month.

Define recurrent UTI

3 or more per year

EpiPen dose

150mcg kids


300mcg adults

Median nerve distribution

Lateral 3.5

Tetanus

Adult:


More than 10 years


Less than 3 doses



Child:


More than 5 years


Less than 3 doses


Men B advice

Fever is common:



- 2.5mg at time of vaccine


- further dose 4-6 hrs later


- 3rd dose 4-6 hrs later


- 4th dose 4-6 hrs later if still has fever only.

Amoxicillin dose

1-11 months: 125mg TDS


1-4 years: 250mg TDS


5+: 500mg TDS

UTI tx in kids

Trimethoprim for three days

UTI referral

More than 2 in 6 months and more than 3 in a year. Any in men!!!

Viagra dose

100mg four a month. Use half.

Down Syndrome explain what they are like

1) learning disability


2) medical problems (hearing, vision, cardiac, obesity, diabetes, fertility)




Severity varies. Everyone with DS is different.



Can have an active and full life

Harmony test done from

Week 10

What is anaemis

Means that you have less RBC's than normal or that you have less Hb than normal in each RBC. This means that less oxygen is carried around in the bloodstream.

Domestic abuse supports

Women's Aid


AMEN

Risk factors for ED

Diabetes


Smoking


Drugs


Alcohol


Vasectomy

How long for Viagra to work

1) by mouth- 30 mins


2) under tongue- 15 mins

Cream for ED

Alprostadiol cream

5 step asthma plan from asthma-ireland

1) take 2 puffs of reliever. 1 at a time


2) sit up and stay calm


3) take slow steady breaths


4) if no improvement. Take 1 puff every 2 minute:



Less than 6- 6 puffs in 10 minutes


More than 6- 10 puffs in 10 mins



5) if after 10 mins no improvement. Call for help and repeat step 4 if ambulance do not arrive within 4 mins

Joints of ankle

Ankle joint


Sub-talar (talus and calcaneus)


Mid-tarsal joint

Syndesmosis

Holds tubular and fibula together

Capsular patterns

Ankle


- dorsiflexion more than plantar flexion at ankle


- equal at subtalar


- limited adduction and medial rotation at mid-tarsal joint

Nerve innervation in hands

1) ulnar nerve: 4.5 and 5


2) median nerve: 1, 2, 3, 4.5

Bedwetting is normal until what age?

Age of 5


ERIC charity page online

Meds for bed wetting

Desmopressin. Risk of low sodium. Only use for short term eg sleepover or holiday . Don't drink for one hour before to 8 hours after to prevent low sodium

Orlistat side effects

Ab cramps


Fatty stools


Leakage/faecal urgency



Causes low fat soluble vitamins (A D E K) so important to have a healthy balanced diet.

Safest anti depressant when breastfeeding

Fluoxetine

Supports for Post Natal Depression

Post natal depression Ireland.ie

MMR vaccine side effects

Pain, temperature , mini measles (small rash 6-10 days after that settles itself)



30 years of experience and evidence with MMR vaccine here in Ireland.



15 years ago in Lancet



The age that children show signs of MMR is generally the age that children are given the vaccine. It is coincidence.



HSE website with info. Immunisations.ie

Who is excused from Jury duty?

Over 65


Doctors/nurses/midwives/dentists/vets/chemists/teachers/


Jury duty within 3 years

Drugs payment scheme

Adult partner and any children under 18 or up to 23 if in full time education. Max €134.

Facts re occurance if SAH

1 in 20 of population over age of 30 harbour an unruotured asymptomatic aneurysm

Symptoms of CKD

Weakness, lethargy, fatigue, oedema, SOB

Safety net for CKD

I'd any illness eg diarrhoea and vomiting he is at risk of damage to kidneys from dehydration so important to maintain hydration and to be reviewed early.

Behavioural issues in kids

Early intervention Team (6 or less years): MDT assessment of children and families needs:



- parenting course


- individual intervention


- group intervention




School Age Team (5-18)

Red flags with PVD

1) rest pain. Severe unrrlentless pain in lower limbs. Worse when legs elevated and improve when sitting or standing



2) night pain



3) all the P's

Don't confuse migraine with

Giant cell arteritis

PMR treatment

15mg OD X 3 weeks


Calcichew


Aspirin 75mg only for GCA!!!!!


Aledronate


Lansoprazole

Steroid side effects

Gastric


Bone thinning


Weight gain


Mania


Immunosuppression

Drugs for incontinence

1) anticholinergic; oxybutynin




2) betmiga




What not to forget in CKD management???

CVD!!!

Resisted lateral and medial rotations at shoulder and muscles

Lateral: infraspinatus


Medial: subscapularis

Hip capsular pattern

Internal rotation more than flexion more than abduction

Stat about domestic abuse

25% of women experience abuse

Causes of secondary amenorrhiea

Pregnancy


Stress/exercise/weight loss


Thyroid


Prolactinoma


Premature menopause

Define premature menopause

Before 40's


Define primary amenorrhoea

Absence of menses at age 15 years in the presence of norm growth and secondary sexual characteristics

How many with raised PSA have ca

1/4 of men will have cancer diagnosed on subsequent biopsy

ACR levels in diabetics and non diabetics

More than or equal to:


2.5 in men


3.5 incwomen




Non diabetics


Greater than or equal to 30 gets ACE-i

Name of living will from hospice

ThinkAhead

Alcohol units/week

17 men


11 women

Alcohol vitamins

Vitamin B1 (thiamine) 100mg TDS


(one TDS)


Vitamin B complex


Vitamin C ( ascorbic acid)



Librium:


15mg QDS for 2 days


10mg QDS for two days



Risk factors for carpal tunnell

Diabetes


Hypothyroid


COCP


Trauma


Arthritis

NOAC of choice

Apixaban

DVT tx

Clexane until scan. 1mg/kg BD SC



Then Apixaban for three months



All need tests if unprovoked:



- CXR


- FBC, serum calcium, LFTs, anti-phospholipids


- Urinalysis


- CT ab/pelvis if over 40



COCP counts as provoked

How to confirm contact dermatitis

Patch testing

How long menopause symptoms last

80% have vasomotor symptoms. Usually last around 2-5 years. 30% have urinary/vaginal symptoms

Website for menopause

Menopause matters

HRT options

Menstruating (cyclical). Femoston



Uterus (continuous). Femoston Conti



No Uterus (continuous). Femotab

HRT risk of breast cancer

Under 50: no additional risk


50-54: slight increased risk


More than 54: from 30/10,000 to 38,10,000

Driving and first seizure

Group 1: 6 months

Transgender support group Ireland

Transgender Equality Ireland

If eGFR less than 60?

Repeat in 2/52 with ACR

Capsular pattern at elbow

Flexion more than extension. Pronation equals supination

Codeine pain meds

Solpadeine (8mg codeine, caffeine)



Co-codamol 15mg codeine



Tylex/co-codamol/Solpadol (30mg codeine)





Side effects: constipation, nausea, light-headedness

ED and anti hypertensives

Older drugs (beta blockers, diuretics). Newer drugs seem to have neutral effects.

Flying and pregnancy rules

Up to 36 weeks (32 if twins). After 28 weeks need a letter to say they are fit to fly!

With PMR what to always ask about???

Eye symptoms

Dementia supports

Helpline 6/7


Publications posted for free


Dementia advisors to help link with services


Day care


Respite


Home care packages


Social clubs


Alzheimer's cafe

Floaters risk factors and causes

Benign age related changes


Retinal detachment


Refer urgently!!!!!



Risks:


Trauma


Cataract surgery


Previous retinal detachment


Near slightness


Age

Mean parental height

Plus or minus 7cm

Recurrent UTI in men think???

STI

Hand foot and mouth

Coxsackie virus


No treatment


Not linked to animals


Scarlet fever

Causes by strep


V contagious. Sneezing, coughing


Notifiable disease


Tonsillitis and then fine red rash in chest and stomach first that then spreads to body


Sandpaper rash


Desquamation as rash settl r


White strawberry tongue


Flushed red cheeks with mouth spared



Avoid school until on antibiotics x24 hours. Contact precaution. 10 days of abx



School is ok 24 hours after and started

Risks for breast cancer

Early menarche (less than 11)


Late menopause (more than 55)


Number of children (reduces risk)


COCP/HRT


Breastfeeding (reduces risk)

Earliest date of possible ovulstion

Shortest cycle length minus 14

How do EllaOne and levo work?

Ella one- delays ovulation X 5 days


Levo- inhibits or delays ovulation X5 days

CI Ellaone

Asthma


Breastfeeding (need to discard x1/52)

Two emergency pills in a month

Levo cannot be given within 5 days of Ella


Ella cannot be given within 7 days of levo

Treating thyroid disease in a pregnant lady

Check if she plans to get pregnant!!!!!

Risks for thrush

1) high dose oestrogen


2) condoms


3) vaginal douching


4) bubble baths


5) tight fitting clothes

What to rule out with recurrent thrush

Diabetes


HIV (blood transfusions, IVDU, multiple sexual partners)


Immunosuppression

Tx recurrent thrush

4 or more episodes per year



Fluconazole 150mg every 3 days for three doses , then 150mg weekly for 6 months.



No evidence to treat asymptomatic male sexual partners



Vulval moisturisers. Friction from sex may cause tiny tears which makes it more prone for candida to thrive

Menieres disease

Inner ear



Vertigo


Tinnitus


Deafness

Causes of vertigo

Vestibular neuritis


BPPV


Menieres


Vestibular migraines

Vertigo red flags

Unilateral hearing loss


New headache


Tinnitus


Double vision


Dysphagia


Ataxia

What tinnitus to refer???

Unilateral


Pulsatile


Dizziness, vertigo, imbalance,


usis


HyperacusisBad effect on life

When to refer squint ?

3 months

Center criteria

3-14 years


Exudate


Tender lymphadenopathy


Temp more than 38


No cough




2-3: test


4: treat empirically!!!!!

Warfarin advice!!!!!

- Take at same time each day


- Limit alcohol- max 2 units/day


- Avoid cranberry juice


- Check with pharmacist about taking any OTC meds eg aspirin avoid


- Let your doc know if you have any falls or injuries


- Do not get pregnant.


- Any dental procedures- tell the dentist!


- carry pt alert card


Anti epileptic of choice in pregnancy

Lamotrigine



If changing or coming meds in pregnancy. Can't drive for 6 months

Driving and epilepsy

First seizure:


6 months and review by neurologist


5 years for group 2



Epilepsy:


Seizure free X 12 months and can only get 3 yr licence. Need to be seizure free X 5 years to get it for 10 years



Group 2: seizure free for ten years off meds!!!!!



Provoked seizures can drive!

Orlistat - targets

Only continue if at least 5% weight loss in 3/12

Metformin starting dose

500mg BD. Max 1g BD

2nd diabetic drug

BMI less than 30: sitagliptin



BMI more than 30: GLP or SGLT

Combo drug for less than 30 BMI

Janumet (Metformin and sitagliptin)

DPP4 drug and MOA

Sitagliptin (Januvia)



MOA: increases insulin produced by the body. Insulin helps control the levels of glucose in your body. It also reduces AMT of glucagon produced. Glucagon is used by liver to make sugar.

GLP-1 drug and MOA

Trulicity ( weekly)


Victoza (daily)



Increases the AMT of insulin produced by the body and reduces the amount of glucagon being produced.

Gastro when back to work

48 hours after diarrhoea has completely settled. Always ask re occupation

Explain CBT

Works by helping you to understand that your thoughts and actions affect how you feel

Sleeping tablets facts

100 people



7 would sleep better (extra 25mins a night)


75: nothing


17: side effects

NF inheritance

Both types are AD. But 50% are new mutation



Learning disability


seizures


Autism


Lisch nodules


Cafe au lait

Haemochromatosis inheritance

AR with incomplete penetrance and variable expressivity.



Test first ferritin and iron. Then if high- do genetics!

PET bp

More than 140 or more than 15 above booking visit

How to delay oeriod

Primolut


Medroxyprogesterone acetate if over 35, smoking

Drugs that can cause hair loss

Carbimazole


Warfarin


Heparin


Chemo

Cause of male pattern baldness

High levels of dihydrotestosterone. (DHT)

Advance Care Directive

Signed into law December 2015, but not yet commenced into effect.

Sciatic nerve roots

L4, L5, S1

Fact re X ray and spine issuee

X rays detect serious pathology in 1 in 2,500 patients

Capsular pattern at neck

Limitations of all movements except flexion

What diabetics need statins

All over 40. Unless planning pregnancy.



Aim.



LDL less than or equal to 2.5 if no CVD. Less than or equal to 1.8 if history of CVD.


Planning pregnancy and diabetic

5mg folic acid


Stop teratogenic meds


Check 7 times a day


Educate re hypos


Retinal and renal screen


Book early


Refer to diabetic centre for pre pregnancy care


Smoking and alcohol

WL on Forxiga

0.5kg per week

Apixaban dose

5mg BD


2.5mg BD if over 80, less than 60 kg, Cr greater than 133

Meds post MI and drivinf

Not for 4 weeks. Ace


BB (erectile Dysfunction) station, anti platelet

Raynaud's history???

Outrule CT disorders:


- morning stiffness


- swollen joints


- rash


- family history



Triggers:


- COCP


- BB


- Migraine meds


- vibrating tools


- smoking

Side effect Nifedipine for Raynauds

Headaches


Flushing


Dizziness

What to tell people with CVD

Can't do much about your non modifiable risk factors - age, gender, genetic



Lots to do with modifiable risk factors !!!!!

Cholesterol advice

Side effects:


- headaches


- ab pains


- nausea


- diarrhoea



Rarely. Muscle inflammation. So tell ur doc if u have muscle cramps pain.



Do not eat grapefruit



Some meds may interfere with statins so tell ur doc!

How to take GTN

Take one spray under tognue and wait 5 minutes. If pain does not ease take second spray and wait another 5 minutes. If pain still there call ambulance.



No Viagra 24 hours before or after. Due to risk of low bp

Side effects of hyperthyroidism

Osteoporosis


A fun


Angina


Heartbfailure

Radioactive iodine

6 months no pregnancy. 4 months for men!!!!!

Reflux tips

Avoid over feeding



Avoid over feeding


Pre thickened feeds


Keep upright for 30 mins after feed


Avoid over feeding


Pre thickened feeds


Gaviscon instead of pre thickened feeds



Ranitidine only if above fails.



Occurs in 50%> settles with age




Ranitidine only if above fails.



Occurs in 50%> settles with age

Marker of CMPA

High pitched screaming


Vomiting


PR blood


Diarrhoea


Crying not fitting with usual evening clusters


Back arching


Clenched fists


Pained face when crying

Colic fact

Cue based care from birth with an average of 10 hours of physical contact a day is associated with 50% less crying!!!!!!!



Purple crying.info

Adequate breastfeed

Adequate WG


More than 5 wet nappies a day


Good latch


Milk is seen in their mouth

PEP

Within 72 hours.



Side effects:


Diarrhoea


Vomiting


Headache

Fibre in irritable bowel

Avoid insoluble fibres eg bran


Use soluble fibres eg oat, ispahulga

Freq of ab pain in kids???

1-2 out of every 10 kids with have abdominal pain

Medications that cause hair loss

Carbimazole


Warfarin


Heparin


Chemotherapy

Zika and baby

Small head


Limb defects


Eyes


Hearing

Zika virus and pregnancy

8 weeks for women


6 months for men


If partner is pregnant use a condom!!!

Symptoms HD

Involuntary movements


Speech and swallow


Short term memory loss


Behavioural

Glaucoma risk factors

Over 40


FH


Short sighted


Diabetes

Red flags for sexual abuse in children

Anogenital bruising


Recurrent UTI


Vaginal discharge


Sexual precocious behaviour


Enuresis


Behavioural change

Domestic violence supports for

Women: Women's Aid


Men: Amen

CF features and risk

Chest infections


Digest food- poor growth



Incidence 1 in 2500

Commonest symptoms of PKD

HTN


Kidney failire

SSRI withdrawal side effects

Like having the flu


- dizziness


- light headedness


- N and V


- irritable


- headaches

SSRI side effects

N + V


Constipation


Sexual dysfunction


Reduced or increased appetite


Discontinuation symptoms

Online CBT

Moodgym

Side effects of alcohol

HTN


Stroke


Heart disease

Alcohol meds

1) Vitamins


Thiamine TDS


Vitamin B complex


Vitamin C



2) Librium


20mg QDS X 2 days


Then 15 mg QDS


Supervised


Daily dispensing

What is MND? Law

Progressive weakness of many of the muscles in the body



Up to 15 years in prison!

Dying

- Care plan in place eg Think Ahead


- Hydration status


- Anticipatory prescribing: pain, breathlessness, anxiety, agitation, nausea, respiratory secretions


- Book-keeping when breath becomes air.

Potentially reversible causes of memory loss

Depression


Thyroid


Vit B12

Dementia bloods

FBC


U and E


Calcium


TSH


Glucose


B12


Folate

Drug of choice for dementia

1) Donepezil. GI side effects. It increases a chemical called acetylcholine. This allows nerve cells in the brain to communicate with each other. People with dementia have low levels of acetylcholine.


2) Thiamine


3) Souvenaid: nutrients required to make new connections in the brain. Difficult to achieve by diet alone.


A fib risks???

Increases risk of stroke X 5 times

Management of PSA results

Less than 2: repeat in 2 years


More than 2: yearly repeat

What is the prostate

Chestnut organ that sits below bladder. It produces semen

How long till baldness

15-25 years from first signs

Causes of gynaecomastia

- Puberty


- Obesity


- Medications- finasteride, TCA, alcohol, steroids


- Hyperthyroidism


- Renal or liver disease


- Cancer: CXR, testicular, prostate, breast


Vasectomy explain

Cut the vas deferens. The tube that takes sperm from the testicles to the penis. Sperm is made in the penis. Once cut. Sperm cannot get into the semencthat comes out during sex.

Aftercare vasectomy

2 samples, 4 weeks apart.

S/E Vasectomy

Not reversible


Risk of failure


Haematoma and infection


Chronic scrotal pain 10%


Does not protect against STI's!

Treatment of premature ejaculation

1) Self help pages


2) masturbating 1-2 hours before sex


3) using a thick condom


4) topical local anaesthetic eg Instillagel


5) couples therapy/ sexual therapy


6) SSRI- Dapoxetine.

Important q in people with seizure

What are your hobbies eg swimming, rock climbing etc

Chicken pox exposure and pregnant

VZIG within 10 days as long as you don't yet have chicken pox symptoms. It may prevent chickenpox and if not, it reduces symptom severity and duration.



You can give it again as long as it's 3 weeks since previous injection

Why sign a DNR?

1) Patient request


2) CPR will not work


3) Burden of CPR is greater than benefit. ie patient will be left with a v poor quality of life!

Risk factors for squint

FH


Prematurity


Facial abnormalities


CP

Homeopathy

Idea that 'like cures Luke's



Remedies are used in small amounts to treat symptoms that they would actually cause in large amounts. Usually from plants.



Evidence in food allergies/hay fever



Good for self-limiting conditions.

Risks from needle stick injury

HIV: 0.3%


Hep B: 6-30% chance


Hep C: 1.8%

Needle stick injury tx

Hep B vaccine


Tetanus booster


PEP if within 72 hours

Risk with needle stick

HIV, hepatitis


CMV, EBV, Parvovirus, malaria

What not to forget with asthma

Triggers!!!!!!!! Cold air, animals, dust

Smoking cessation meds

Buproprion (Zyban)



Take it while still smoking and stop 1-2 weeks later. 150mg X 6 days then BD for 7-9 weeks.



Varenicline (champix). Same story

COPD management



+ Always mention?????

FEV1 more than 50%:


1) SABA eg Ventolin


2) LAMA eg Spiriva Respimat


3) LABA and ICS eg Seretide or Symbicort



FEV1 less than 50%


1) SABA eg Ventolin


2) LABA and ICS eg Seretide or Symbicort




Mood!!!!!!!!!


Gastro rules

Not until 48 hours clear of symptoms


No swimming x 2 weeks

CI menopause

Suspected breast/endometrial cancer


Undiagnosed genital bleeding


VTE hx


Liver disease


Active gallbladder disease


Pregnancy/breastfeeding

Tests for infertility

Irregular cycle: LH, FSH


TFTs


Day 21 Progesterone to make sure you are ovulating


AMH


Semen analysis



Modifiable risk factors: bmi, smoking, drugs, stress

COCP and age

Stop aged 50!


Stop aged 35 if smoking 15 plus a day

Chlamydia testing

Wait till 2 weeks post episode

How many people with RA have a positive test???

70%

Acne mg

Facial wash with 2% salicylic acid. Eh clearasil



Moisturise with no oil eg effaclar



Make up- non comedomic



General. No scratch pick, fresh air and exercise ,balanced diet




1) BPO mane CAN BLEACH clothes!!!


2) BPO mane and topical retinoid


3) BPO mane and Diabetes/abx



Tetralysal or erythromycin if female



Min 3 months. Max 6 months.


Skin formuls

A symmetry


B order irregular


C olour variation


D iameter more than 6mm


Elevation


Firm


Growing

Psoriasis explain

Affects skin, but other part of body such as nails and joints.



Normally skin regularly sheds its top layer. In psoriasis the top layer sheds too quickly create omg a thickened, whitish appearance and possible flaking. Blood vessels underneath come nearer the surface giving an underlying redness.

Mg psoriasis

Meds:



1) emollients


2) vit d eg calcipotriol mane and potent steroid evening.


3) if scale thick- use topical salicylic acid



Avoid triggers:


Alcohol


Smoking


Stress


Beta blockers

If breast feeding with CMPA

Add 1000mg calcium and 10mcg vitamin to prevent nutritional deficiencies

Fingertip rule

Hands: 1 unit


Chest and abdomen: 7 units


Back: 7 units

What to screen for with gout

HTN


CVD


Diabetes

When to treat shingles

Within 72 hours and


- 50+


- less than 50 if


Ophthalmic involvement


Immunocompromised


Non truncal


Mod/severe pain


Mod/severe rash



Not in children!!!!!!!!

Chicken pox VZIG

Works until 10 days post exposure

Chicken pox risks to mam

Chest infection


Liver


Brain


Death

Chicken pox risks to baby

36/40 to 7 days post psetun. They may get chickenpox



Less than 28 weeks. Small chance of abnormalities to legs, arms eyes brain bowel.

Website for enuresis

ERIC

Vaccine covers how many cancers?

70% of cancers

Causes of pubertal delay???

90% temporary delay



Systemic illness


AN


Chromosomal eg Turner's


Hypothyroidism


Raised prolactin

Describe concussion?????

Disturbance in brain function rather than structure. So imaging does not usually detect abnormalities.

Rules post concussion

Rest x24 hours then staged rehab


No alcohol


No sleeping tablets


Paracetamol or codeine


No aspirin or anti-inflammatory meds


Do not drive, train or play sports until cleared!!!

Hep C testing

1) Check hep C antibody. Window period of 3-6 months. So recheck in 6 months.


2) if positive. Check HCV RNA.



Positive = active hep c

Hep C management

1) Refer


2) Stop alcohol


3) Stop spread: condoms, needs sharing


4) Contact tracing


5) Test for:


HIV


Hep A


Ferritin


Glucose


LFTs

TIA

Age over 60


BP more than 140/90


Clinical features. 2 for unilateral weakness. 1 for speech


Duration. 2 for over 60 mins. 1 for 10-59 minutes


Diabetes.



Less than 4: aspirin 300mg and seen in one week


More than 4: aspirin 300mg and seen now!!!

Website for colic

Purple Crying!

Red flags with vertigo

Isolated vertigo with nystagmus is unlikely to be due to a central cause



- unilateral hearing loss


- new headache


- tinnitus


- double vision


- dysphagia


- ataxia



If so think: MS, tumours, vascular

Menieres triad

Vertigo


Tinnitus


Hearing loss

Tx for colic

1) cue based care


2) skin to skin


3) ensure correct feeding technique


4) winding


5) probiotics


6) baby massage


7) SUPPORT FOR MAM



Purple Crying 😀

Doctor I'm afraid I might get dementia

Non modifiable risk factors.


Age


Down syndrome


FH of first degree relative


Sex



Modifiable


Smoking


Low saturated fats, anti oxidants


Alcohol


Exercise


Weight


Mental activity


Exercise for kids and who get referred

60 mins a day



Refer:


- Learning disability


- Short stature


- Dysmorphic features

Obesity websites

Get Ireland active


Littlesteps

Cause of delayed puberty?

90% temporary



Other:


Systemic illness


Thyroid


Prolactin


Chromosomal eg Turner's


A.N.

What to avoid with constipation

Filling up on milk as this can lead in a poor diet!

Enuresis is normal under age of???

5

Explain shingles

Sleeps inside your nerves. Hibernates.

FTU

1 = hand space




Chest and abdomen = 7 units


Back = 7 units



Most eczema is not related to CMPA

Mg gout

1) Naproxen first line or else colchicine



2) screen for CVD and diabetes



3) avoid triggers:


- alcohol


- purines (red meat, seafood)


- drugs (aspirin, diuretics)


- CKD



4) Lifestyle


Rest


Fluids


Ice pack



5) Prevent if more than 1 attack in 13 months



Allopurinol



With


-Colchicine for 3 months


Naproxen for 6 weeks



6) Life long uric acid levels every year!!!!!

CI levo

Epilepsy


Weight over 75mg need to double dose!!!

Risk of pregnancy PP???

From day 21!

Best time to have smear

Mid cycle


Avoid sex x24 hours prior

ED meds

Viagra: take it an hour before. Lasts 4-5 hours



Cialis: lasts around 36 hours.



Side effects = headaches

Who to refer with a limp???

Less than 3 years


Unable to weight bear


Fever


Older than 9 with reduced ROM at hip (to exclude SUFE)

Risk of infection from a needle stick

HIV: 0.3%


Hep B: 6-30%


Hep C: 1.8%



Also risk of:


Parvovirus


CMV


EBV

UTI guidelines for tests

Less than 3 months get referred for tx


Less than 3 years get referred if no improvement after 24-48 hours



Tests:


- less than 6 months: ultrasound within 6 weeks. If atypical get ultrasound then and follow up DMSA and MCUG



- 6months to 3years: ultrasound during infection if atypical AND DMSA later on



- over 3 years: ultrasound during infection if atypical




All recurrent UTI: ultrasound and DMSA




Frontanelles close when

Anterior: 8-12 weeks


Posterior: 12-21 months



Refer if premature closing

Acne rosacea tx

1) avoid triggers (alcohol, heat, exercise)



2) Mirvaso gel PRN. Works within 30 mins and lasts up to 13 hours



3) top metronidazole

Familial hypercholesterolaemia

AD



Exam


Tendon xanthomatosis


Xanthelasma


Corneal arcus



Total child more than 6.7


Total adult more than 7.5

Why sign a DNR???

Patient request


CPR will not prolong life


Burden of CPR is greater than the benefit. ie patient is likely to be left with a v poor quality of life!

When to investigate neck lump???

If it persists more than 6 weeks.

Center criteria

3/4 out of the following:


- fever


- purulent tonsils


- cervical adenopathy


- no cough

Tests for SIJ???

Telescope


PSIS asymmetry


FABER produces pain in the back

Ages for hip pathology

4-10: Perthe's


10-15: SUFE


Late teens to 40's: FAI

Mallet finger

Rupture of extensor tendon. Cant extend

Jersey finger

Rupture of flexor digitorum profundum

Tx for premature ejaculatiom

Dapoxetine (SSRI- short-acting)

What is the prostate???

Chestnut sized organ.


Sits under the bladder


Produces semen

Causes of Gynaecomastia?????

- Physiological


- Obesity


- Medications- alcohol, finasteride, PPI, anti psychotics, anti depressants


- Hyperthyroidism


- Renal/liver disease


- Cancers

DPP4 side effects and CI

CI: Pancreatitis



Side effects: nausea, GI upset, diarrhoea

GLP side effects

GI symptoms


Increases HR



CI: pancreatitis, thyroid cancer



Benefits: Weight loss

Mg HRT

1) Lifestyle


Alcohol


Smoking


Diet


Weight bearing exercise


Layer clothing


Evening primrose



2) HRT



3) SSRI



4) Bloods to outrule other conditions


Thyroid


FBC


Lipids


Glucose

CI HRT

1) suspected cancer


2) Undiagnosed genital bleeding


3) VTE hx


4) Liver disease


5) Galladder disease


6) Pregnancy/ breast-feeding


7) CVD

HRT and breast cancer risk

Less than 50 = no risk


50-54 = small increased risk


Over 54 = 30/10,000 to 38/10,000