Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
25 Cards in this Set
- Front
- Back
the definition of pH dependent on H+ ion activity in a given solution is?
|
pH = -log(aH+)
|
|
the -log(aH+) is equal to the -log of what two values?
|
1. the H+ ion activity coefficient
2. The H+ ion concentration |
|
what is the normal pH of blood plasma in the body?
|
7.4
|
|
what concentration of free H+ ions is this?
|
50 nM
|
|
what are the two types of acids or bases?
|
1. Volatile
2. Nonvolatile |
|
define a volitile acid or base?
|
have gaseous components with which they are in equilibrium with
|
|
what are the two types of nonvolitile acids or bases?
|
organic and inorganic
|
|
what concentration of volitile acid, CO2, does the body produce per day?
|
14 moles per day
|
|
what is the total concentration of nonvolitile acids produced in the body per day?
|
60 millimoles per day
|
|
all nonvolitile acids or bases are removed from the body by which organ?
|
the kidneys
|
|
the most produced volitile acid in the body is excreted by which organ?
|
the lungs = CO2
|
|
a proton donor is a?
|
acid
|
|
a proton acceptor is a?
|
base
|
|
what allows for the property of buffering in a solution?
|
protons ability to reversibly bind many different substances
|
|
How is disolved PCO2 calculated?
|
PCO2 x solubility
|
|
describe the Ka' for disolved CO2 in the blood?
|
Ka' = ([HCO3-][H+]) / (dissolved CO2*)
* = PCO@ x solubility coefficient |
|
what is the typical Ka' for dissolved CO2?
|
10 to the -6.1
|
|
what is [HCO3-] normaly in blood plasma?
|
24 mM
|
|
what is PCO2 in normal blood plasma?
|
40 mmHG
|
|
what is the solubility coefficient for CO2?
|
.03 mM/mmHg
|
|
how do weak acids and bases act as buffers?
|
the react with free protons and thus minimize pH differences
|
|
what is the equation for determining buffering power for a given vase or acid?
|
buffering power = the amount of base added divided by the resulting change in pH
|
|
what are the two major determinants of the effectiveness of a closed buffer?
|
1. its concentration
2. the proximity of its pK' to the pH of the solution |
|
when is a closed buffers buffering power at a maximum?
|
when pH = pKa'
|
|
the buffering power of a closed buffer is directly proportional to?
|
its concentration
|