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7 Cards in this Set

  • Front
  • Back

How is carbon dioxide transported?

1/ 5% dissolved directly in plasma


2/ 10% combined w/haemoglobin to form carbaminohaemoglobin


3/ 85% transported in form of hydrogencarbonate ions

How are hydrogencarbonate ions formed?

1. CO2 diffuses into blood; some enters RBCs


2. CO2 combined w/water to form weak acid called carbonic acid


3. This reaction is catalysed by enzyme carbonic anhydrase


4. Co2 +H2o -> H2CO2


5. Carbonic acid dissociates to release hydrogen ions (H+) and hydrogencarbonate ions

What is the chloride shift?

When hydrogencarbonate ions diffuse out of RBCs


- charge inside RBC is maintained by movement of chloride ions from plasma

What effect do hydrogen ions have on the contents of a RBC?

The contents become very acidic


to prevent this- hydrogen ions = taken up by haemoglobin to produce haemoglobinic acid


Haemoglobin is acting as buffer

How is oxygen released?

Partial pressure of respiring tissues is lower than in lungs


-bc its been used for respiration


Thus oxyhaemoglobin dissociates and releases oxygen into tissues

What is the Bohr effect?

When co2 is present in haemoglobin, hydrogen ions displace oxygen on it


- as result oxyhaemoglobin releases more oxygen to tissues


Where tissues are respiring more = more Co2


as result - more hydrogen ions produced in RBC


- makes oxyhaemoglobin release more oxygen


More co2 present = haemoglobin less saturated w/oxygen


Makes oxyhaemoglobin curve shift down and right

What does the Bohr effect result in?

Oxygen being more readily released where more carbon dioxide is produced


-from respiration


What muscles need for aerobic resp