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Fate of Glu-6-P

1. Glycolysis to pyruvate


2. Glycogenesis/Gluconeogenesis/Glycogenolysis


3. HMP shunt pathway


4. Lipogenesis


5. Carbon skeleton for non essential amino acids.

Fate of Pyruvate

1. Oxidative decarboxylation to acetyl CoA in mitochondria


2. Reduced to lactate


3. Carboxylated to Oxaloacetate (B7)


4. Converted to malate (malic enzyme)


5. To Alanine - transamination (B6)


6. Reduced to ethanol, yeast/bacteria

PFK1 activators

1. AMP/ADP


2. K+


3. Fru-2,6-BP

PFK1 inhibitor

1. Mg++


2. ATP


3. Citrate