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24 Cards in this Set
- Front
- Back
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c-myc
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oncogene *t(8:14)*, burkitt's lymphoma
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bcl-2
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oncogene (t(14:18)), follicular and undiff lymphomas
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erb-B2
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oncogene, breast, ovarian, gastric Carcinoma
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ras
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oncogene, colon ca
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L-myc
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oncogene, lung tumor
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N-myc
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oncogene, neuroblastoma
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ret
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oncogene, MEN(II and III)
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Rb
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tumor suppressor gene, (13q) retinoblastoma, osteosarcoma
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BRCA1 and 2
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tumor suppressor gene, (17q, 13q), breast and ovarian ca
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p53
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tumor suppressor gene, (17p-the only p) most human cancers, Li-fraumeni syndrome
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APC
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tumor suppressor gene, (5q) colorectal ca
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WT1
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tumor suppressor gene, (11q) Wilms' tumor (kidney embryo stuff)
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NF1
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tumor suppressor gene, (17) neurofibromatosis 1 (von recklinghaussen) cafe au lait, lisch in iris
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NF2
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tumor suppressor gene, (22q) neurofibromatosis 2 (bilat acoustic neuromas
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DPC
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tumor suppressor gene, (18q) pancreatic ca
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DCC
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tumor suppressor gene, (18q) colon cancer
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CEA
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tumor marker, colorectal/pancreatic ca (also made by gastric/breast ca)
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alpha-fetoprotein
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tumor marker, hepatocellular canonseminomatous germ cell toumors of testis
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beta-hCG
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tumor marker, Hydatidiform moles, Choriocarcinoma, Gestational trophoblastic tumors
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CA-124
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tumor marker, ovarian, malignant epithelial tumors
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S-100
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tumor marker, melanoma, neural tumors, astrocytomas
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bombesin
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neuroblastoma, (lung and gastric ca)
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TRAP
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hairy cell leukemia
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alk phos
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mets to bone, obstructed billiary disease, paget's
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