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29 Cards in this Set

  • Front
  • Back
What regulates calcium?
PTH
Calcitonin
Activated vitamin D
What is the relationship between Calcium and Phosphorus?
they have an inverse relationship

increase in phosphorus decreases calcium in plasma
What ways does PTH effect calcium?
-increases tubular absorption of Ca
-increases reabsorption of bone
-Promoting activation of Vitamin D
Where is calcitonin produced?
C cells of the thyroid gland
How does calcitonin affect calcium?
inhibits PTH so Ca is decreased
How does Vitamin D affect calcium levels?
it increases calcium from the intestines and enhances PTH activity
What is apparent hypocalcemia?
When there is a decrease in albumin

50% of calcium is bound to albumin
What is the effect of acidosis on calcium? Alkalosis?
increases ionized calcium
decreases ionized calcium
What are the four common diseases that cause hypocalcemia?
renal disease
ethylene glycol toxicosis
panreatitis
Eclampsia
What are signs of hypocalcemia?
nervousness, anorexia, hyperventilation, numbness, tetany, seizures
T/F

The pancreas is the only source of intrinsic factor in cats.
True

it requires vitamin B12 for absorption
If you have an animal that presents with a normal TLI with a low cobalamin have what problem?
they have GI disease
What can exocrine pancreatic insufficiency mimic in cats?
malabsorption

use a TLI to distinguish
What are the sources of intrinsic factor in dogs?
stomach and pancreas
What vitamin will be decreased with exocrine pancreatic insufficiency?
B12
How does exocrine pancreas insufficiency affect bacteria, folate and B12?
bacterial overgrowth
increased folate
decreased B12
If you run a folate and a B12 test on an animal with a normal TLI what do increases and decreases of these test indicate?
Increase:
-bacterial overgrowth

Decrease:
-protein losing enteropathy
What are the common causes of hypercalcemia in dogs?
hypercalcemia of malignancy
What are the common causes of hypercalcemia in horses?
renal disease
What are the signs of hypercalcemia?
PU/PD, lethargy and weakness
At what level do you see tissue mineralization in hypercalcemia?
when the calcium multiplied by phosphorus is greater than 60
What additional things do you want to look for in an animal with hypercalcemia?
cancer - check lymph nodes
Renal disease
Mass in cervical regions
history of vitamin D ingestion
What are causes of lymphocytosis?
lymphocytic leukemia
Ehrlichiosis

can cause neutropenia
How can you treat hypercalcemia?
fluids
diuretics
calcitonin
glucocorticoids
What influences phosphorus levels?
PTH- decrease P
Calcionin - decreases P
Vitamin D - increases P
What can cause a hypophospotemia?
metabolic acidosis
diabetic ketoacidosis
What is a common cause of hyperphosphotemia?
decreased GRF
ruptured urinary bladder
Urethral obstruction
What are two ways that ruminants loose Mg? Horses?
\
Grass and milk tetany
Through sweat
When do you usually see hypermagnesia? What is this similar to?
When renal function is compromised
Potassium and Phos