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178 Cards in this Set
- Front
- Back
DDx
What type gland? apo mero holo |
Fordyce granules
holo - sucide bomber [sebaceous gland] sebaceous gland is connected by a duct to surface / in dermoid cyst, not like this apo - 아퍼 일부분이 떨어져 나감 LEC Xanthoma series[Verruciform X; Xanthogranuloma] CA [mucoepidermoid C ; clear cell C] |
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Unique histologic feature
DDx |
LEC
in slide u can see - capillaries on the roof of cyst 1. parakeratosed SSE [ SSE is thin, parakeratosis is thick] 2. beneath basal cell, there is lymph ts including follicullar lymph ts 3. beneath lymph ts, loose connective ts DDx : BCC and lymph node Epithelium overgrowth in the lymph ts ^ BCC와 조직학적으로 같다. 위치로 구분 in tosillar crypt there is a epitheium |
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what Arrow?
What is this? |
Microabscess --> Psoriasis form inflammation
Geographic tongue DDx Candidiasis [ when there is erosion , think candida always ] Erosive lichen planus Psoriasis |
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Crouzon's and Apert's syndrome
TWO feature AD ? |
Premature cranial suture closure
Syndactyly AD |
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DDx of nasopalatine duct cyst?
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Radicular cyst
Primordial cyst |
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DDx
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Thyroglossal Tract Cyst [Tract cyst]
DDx Thyroid-itis Hashimoto's ds Simple Goiter |
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what?
DDx THREE |
Stafne's bone defect
Langerhans cell ds Hematopoietic marrow defect Ossifying fibroma " size is small [ not odontogenic fibroma because it is Mn post site] |
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DDx
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Simple bone cyst
Giant cell granuloma / OKC [ usually not so big ] ^Ameloblastoma usual shows multi-locular pattern and foggy Simple bone cyst : true cavity[not cyst] , no ts |
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swelling in this are, u must think this first. What is this?
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Mucocele
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ranula and mucocele 's difference?
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ranula - lesion in submandibular duct, Wharton's duct
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DDx of mucocele?
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cyst, lipoma, neuroma
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dermoid cyst's oral cavity occurrence?
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mouth floor
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What is this?
and oral occurrence? DDx TWO |
Dermoid cyst
Mouth floor DDx; ranula and TG cyst ; LEC [but LEC can occur lateral border of tongue ] But dermoid cyst cross midline and big!! |
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Ameloblastoma DDx
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Myxoma
Giant cell granuloma It's ameloblastoma Ah my god |
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What?
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Ameloblastoma
reverse polarity SR like space mature collagen - less nuclei |
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blue tumor?
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AOT
there are much cells young occurrence |
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What is this?
D and C, S ? DDx Three |
AOT ; DAO
D - duct C - calcification S - swirls of spindle cells DDx - Dentigerous cyst [ "AOT usually accompany with unerupted teeth, 75% with canine ] , Ameloblastoma , OKC |
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What is this?
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CEOT
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CEOT
Two micro fx? |
Epithelial strand + Amyloid or calcification
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What's Liesegang's ring ?
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Concentric calcification in amyloid of CEOT
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Which cystic lesion occur frequently on Mouth floor? Four
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Ranula
LEC Dermoid cyst Thyroglossal tract cyst |
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SCM 을 따라서 생기는 cyst로 SSE 와 lymph ts로 구성된 cyst wall을 가지는 것은?
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Branchial cleft cyst
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Gorlin-Goltz triad?
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multiple OKC, basal cell carcinoma, bifid rib at early age
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Dx and DDx TWO
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OKC
usually unilocular[small] and including teeth DDx :dentigerous cyst, radicular cyst Hx feature 1. corrugated , parakeratosed thin cyst wall without ridge 2. hyperchromatin pallisaded basal cell layer |
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Another name of Bohn's cyst ?
epi originated from ? |
Dental lamina cyst [ gingival cyst of newborn]
Epi of Serres |
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Gingival cyst of adult usually occur mulitply [ T / F ]
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False
Newborn occurs multiplely but not for adult |
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Is this OKC?
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Not OKC
Thin wall and no ridge but not corrugated and no hyperchromatin palliasading cells * this is the gingival cyst of adult Gingival cyst of adult's intraosseous counter part is LPC |
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What is this?
What does the black arrow points? |
COC
Ghost cell Cyst lining [epithelum] shows reverse polarity like ameloblastoma |
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@ Myxoma
1. DDx 2. Age 3. Mx or Mn 4. slow or fast growing 5. what is extracellular matrix ? |
1. Ameloblastoma, Giant cell Granuloma Ah My God
2. 20-30 3. Mn 4. slow 5. acid MPS[hyaluronic acid and chondroitin sulfate] |
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What is this?
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AOT
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Does ameloblastoma produce radio-opaque image?
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no
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DDx this
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Radicular cyst
Lateral periodontal cyst COD and Langerhans cell [ but these are unilocular] But, this is mulilocular radiolucency Ameloblastoma and OKC |
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DDx
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Dentigerous cyst
HYPERBLASTIC FOLLICLE AOT [75% case with canine] COC [ 30% with teeth] ---> but usually Mx ant then Mn ant CEOT [ over 50% with impacted teeth ] but usually with 3rd molar CEOT : 40-50 COC ; 20-30 = Amelo, Myxoma Giant cell lesion = 20 not ameloblastoma " not multilocular |
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DDx
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Odontoma [complex]
AFO > CEOT > COC CEOT is less common than COC but includes 3rd molar not AOT " not ant mx AOT have female preferrence |
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What is this
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AF
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Which teeth tends to be affected mostly by cementoblastoma?
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lower 1st molar under 20 yrs
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DDx
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cementoblastoma
Periapical COD Ossifying fibroma Dx= cementoblastoma pink and purple tumor |
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Myxoma age?
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20-30
same as ameloblastoma |
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What is this?
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SOT [Squamous odontogenic tumor]
looks like ameloblastoma " epithelial nest in the mature fibrous connective ts ; BUT there is no reverse polarity in basal cell layer ^ameloblastoma basal cell layer is columnar epi |
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What is the diff bet Odontogenic fibroma and its WHO variant?
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1.much more odontogenic epi in WHO type
2.cellular mesenchymal swirls |
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Which odontogenic tumor is more frequent in femles?
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1. Odontogenic fibroma
2. AOT 3. Giant cell granuloma not COC |
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Which tumors usually occur in Mx?
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AOT and odontogenic fibroma [ not ossifying fibroma - that occurs in post mn]
/ and COC |
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DDx upper and lower
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upper is odontogenic fibroma / lower is myxoma
odontogenic epi - basememt memb is thick and 찐한 핵 with collagen ---> Odontogenic fibroma without collagen ---> only fibroblast -----> myxoma |
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Dx?
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Fibrous dysplasia
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List 3 type of Fibrous dysplasia
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1. monostotic
2. polyostotic 3. Albright syndrome - polyostotic + skin pigmentation + endocrine dysfunction |
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Dx and
DDx [on Rx and on hx] |
cementifying fibroma[=Ossifying F/ Cemneto-Ossifying F]
DDx 1. Radio DDx ; Focal COD, odontoma 2. Histo DDx ; Fibrous dysplasia |
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What?
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Langerhanscell ds
Coffee bean nuclei |
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Langerhans cell ds's sex preference?
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Male
Wide age range Looks like radicular cyst or periodontal lesion |
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Langerhans cell ds's immunohistochemical marker 2?
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S100 and CD1a
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Dx?
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Giant cell lesion
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Cherubism's sex preference?
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Boy
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What?
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Carcinoma in situ
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What is this?
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LEC
It is yellowish and small nodule U can see small capillaries on the nodule |
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What?
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Ameloblastoma Cherubism > Myxoma,Giant cell lesion
not OKC - OKC is usually unilocular and not so big like amelo |
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What?
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Ameloblastoma
DDx: Myxoma, Giant cell lesion |
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What?
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Cementoblastoma
by cementoblast under 25 yr entire mass shud be outlined by PDL but in COD mass is separted from tooth by PDL and COD usually occurs mutliply |
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Dentigerous cyst vs OKC
DDx point? |
Thickness and corrugation
epi of Dentigerous cyst is relatively thick to OKC and no parakeratosis[corrugation] |
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OKC
male or female and AGE? |
20-30 MALE
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OKC site?
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RAMUS
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Dx
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central giant cell granuloma
cross midline |
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Dx?
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Odontogenic Myxoma
1st DDx is ameloblastoma 2nd is Giant cell lesion |
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Dx?
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AF
focus on CT CT is different from Ameloblastoma's CT Immature stroma : no collagen fiber and elongated nuclei of stromal cell |
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Which is diff bet AF and ameloblastoma?
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age and collagen
AF occurs at younger age. 2nd decade and do not have collagen but do have enlongated nuclei of fibroblast |
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Dx?
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Langerhans cell ds
red tumor |
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Dx?
Sex and Age preference? |
Langerhans cell ds
Male and wide age range red arrow --> eosinophil [ not needed to dx] |
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Which of above is plasma cell?
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2
3 = monocyte 1 = PMN |
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What is Parulis?
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mass of granulation ts at opening of sinus tract by perforation of cortical bone
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Epulis
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swelling of gum ; gum boil
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Can u see reverse polarity at COC?
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yes
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What is this?
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Condensing Osteitis
There shud be damaged tooth cementoblastoma is not related to damaged tooth |
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Dx?
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Proliferative periostitis
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Giant cell lesion age preference?
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under 20
thus DDx with cherubism [ male, boy ] GG ==> glamorous girl [ girl >> boy ] |
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Dx?
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Chronic hyperplastic pulpitis
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Which syndrome have Micrognathia and no cheek bone?
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Treacher-collins syndrome
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Dx?
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commissural lip pit
mmss |
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Dx?
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Geographic tongue
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Dx?
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Median Rhomboid Glossitis
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Dx?
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Benigh Migratory glossitis
point : white border |
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Dx?
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OKC
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What is the most common developmental cyst?
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Nasopalatine duct cyst
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epi of nasolabial cyst?
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PCCE
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Which cyst has this?
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This epi is PCCE
nasolabial cyst has this |
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Thyroglossal tract cyst's sex and age?
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Young
NO SEX mark on neck!! so, no sex preference |
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which cyst in mouth has teratoma-like feature?
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dermoid cyst
teratoma -ectoderm, endoderm, mesoderm |
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odontogenic epithelium's main feature?
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thick basal lamina
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49 yr patient
Dx? |
GOC--- Mn anterior
Glandular odontogenic cyst Point : multiple microcyst, very thick SSE and cluster of mucous cell [like gland] Aggressive cyst |
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Buccal bifurcation cyst is a developmental cyst T or F
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False
Inflammatory cyst |
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Pseudocyst 4
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ABC : aneurysmal
SBC : simple SBD : stafne Hematopoietic bone marrow defect |
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Virus factors for oral cancer?
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HPV, EBV, HIV
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Bacteria factors for oral cancer?
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Syphilis, Candidiasis
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High risk part of oral cancer that u shud know
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Retromolar trigone and soft palate
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Verrucous carcinoma can go SCC?
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Yes
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List 1-6
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1.Parotid
2.Buccal 3.Submental 4.Submandibular 5.Deep cervical 6.Superficial cervical |
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hereditary tooth disorder associated with opalescent tooth coloration, bell shaped crowns and obliteration of pulp chamber.
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Dentinogenesis imperfecta
Type I is ass with Osteogenesis imperfecta |
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Most common odontogenic tumor?
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odontoma
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Which tumor have snow flake inside ?
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AOT
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Small number of teeth?
one or two missing |
Hypodontia
over 6 missing --> Oligodontia |
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frequently missing teeth?
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3rd molar > second premolar > lateral incisor
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Enamel pearl predilection site?
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Frequently found on roots of permanent maxillary molars
Occurs on the roots at the Tri-furcation area |
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Dx?
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Dens Invaginatus
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Is there tooth resoprtion in Giant cell lesion?
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Yes
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Giant cell lesion is related to hyperparathyroidism?
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Yes
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Fibrous dysplasia and Paget's ds have same age range
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False
Fd ---> much younger Paget ----> over 65 |
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A ; ENAMEL organ
B ; dental papilla C ; dental follicle |
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Black box?
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Odontoblast
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Unicystic ameloblastoma's age range?
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teenager
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Teenager oral tumor?
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Odontoma and AOT
Odontoma --> AFO-->AF-->UA Odontoma and AFO Ameloblastic fibroma Unicystic Ameloblastoma AOT [girl] |
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arrange below from frequent to rare order
CEOT AOT SOT COC |
AOT [about 7%] > COC [1%] > CEOT [not common] >> SOT [very rare]
호발연령 10대 >____ 20~30_____ > 30~40________ > 모름 |
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Dx?
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Clear cell odontogenic tumor [very rare]
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Compound odontoma site?
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Maxilla anterior
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COC site?
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Incisor ~ premolar
- CEOT와 같다. 그러나 CEOT는 Mn소구치부, COC는 Mx 소구치부 둘다 midline을 향해 성장한다. |
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Classification of oral white lesions
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white lesion ---> dry and rub off
DRI AN developmental reactive infectious autoimmune neoplastic |
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Dx?
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White sponge nevus
if rubbed, peel off some but not at all |
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Best way to Dx white sponge nevus?
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invest familial hx [ Autosomal domiant ]
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Histological fx of white sponge nevus?
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Perinuclear condensation of keratin
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Dx?
it is bilateral and disappears when being stretched |
Leukoedema
Upper right side of ts that is stretched looks normal Histologically same as white sponge nevus but much small |
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Parakeratin layer of hyperkeratosis has granular cell layer?
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No.
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we can see linea alba even in edentulous patient
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False
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What is morsicatio?
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chronic chewing
buccarum, labiorum, linguarum |
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Dx?
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Nicotinic stomatitis
- enlarged palatal gland |
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Dx?
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Tobaco pouch keratosis
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Does tobacco pouch keratosis go malignant transformation?
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No. rare
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Is nitcotinic sotomatitis considered premalignant?
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No. just reactive white lesion
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Dx?
premalignant? |
Submucous fibrosis
premalignant Trismus and burning sensation |
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which percent of Actinic cheilitis goes SCC?
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10%
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Dx?
Hx feature |
Actinic cheilitis
CT change by solar --solar elastosis CT goes blue and acellular |
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Contact stomatitis is reactive lesion
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False
Allergic. there is huge lymphocyte infiltration |
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Which type of candidiasis can u remove white patch?
a. Pseudomembranous b. Chronic hyperplastic |
A.
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Does PVL [ proliferative verrucous leukoplakia ] have some connection to tobacco or women?
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tobacco no
female >> male |
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Dx?
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Candidiasis
hyperplastic epi + very long rete pegs ---> long standing fungal infection hypae |
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What is Primordial cyst?
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치아가 있어야 할 자리에 생기는 cyst
--->3rd molar region에 주로 생김 |
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Which tooth usually has connection with AOT?
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canine
AOT --> 75% with canine |
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Which of following Cyst have more connection with impacted teeth?
a. COC b. CEOT |
CEOT
CEOT ; 50% but COC ; 30% |
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syndrome ass with craniosynostosis, syndactyly, maxillary hypoplasia and clefting
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Apert syndrome
1st branchial arch syndrome like Crouzon |
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Fibrous Dysplasia is more common on Mx or Mn?
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Mx
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Mx with Fibrous Osseous lesion will be more susceptible to infection or osteosarcoma [ T / F ]
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True
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In fibrous dysplasia , u can see certain mutation including G protein. These are lowered cAMP by low activity of adenyl cyclase and expression of c-fos oncogene. [T / F]
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First is True, but second is false
increased activity of adenyl cyclase , then cAMP UP |
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A group of fibro-osseous lesions limited to alveolar bone is called?
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Cemento-osseous dysplasia
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3 type of cemento-osseous dysplasia?
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Focal
Periapical Florid |
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Which is the most common fibro-osseous lesion?
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Cemento-osseous dysplasia
- Fibrous dysplasia and ossifying fibroma are histologically similar |
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Guess ?
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Focal Cemento-osseous dysplasia
- predilection for posterior mn u can also think Radicular cyst [but tooth is intact ] and Langerhans cell ds - not ameloblastom b/c it is usually mulilocular |
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Diff bet periapical COD and Florid COD?
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Florid involves posterior area in addition to anterior
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Ossifying fibroma = Cemento-ossifying fibroma = cementifying fibroma?
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True
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Most common site for Ossifying fibroma?
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Mn premolar and molar
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Juvenile aggressive Ossifying Fibroma vs Ossifying Fibroma?
a. pt age b. site c. clinical behavior |
a. 11 yr vs 30-40
b. Juvenile aggressive prefer Mx than Mn c. rapid enlargement and penestration |
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Dx?
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Paget's ds
over 65yr |
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What is this and the characteristics?
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Sebaceous gland
Polyhedral shape cell and dark centered nuclei holocrine secrtion type |
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What is this?
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Dermoid cyst
sebaceous gland - lipid [hair, skin]를 만드므로 pale하게 stain되고 안에 lipid droplet이 많고, ovoid shape |
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Dx?
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COC
cyst lining has some reverse polarity |
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Dx
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CEOT
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Dx?
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Ameloblastoma
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Dx?
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Ameloblastoma
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Amelogenesis imperfecta is inherited by which way?
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all the way possible
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Dx?
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Turner's tooth
[Focal enamel hypoplasia] |
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Chronological enamel hypoplasia
internal resorption external resorption intrinsic staining extrinsic staining Taurodontism Talon cusp |
Be aware
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Most common congenital cyst in neck?
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TG tract cyst
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Gingival cyst of newborn 's predilection site?
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Mx anterior
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Is Residual cyst developmental?
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No, inflammatory cyst
LPC ---> developmental cyst |
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Which radio-lucent lesion usually occurs with odontoma?
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COC
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Which percent of odontogenic fibroma has occurred with unerupted tooth?
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33% [1/3] = like COC
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COC age range?
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20-30 same as amelo and myxoma
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Diff bet BCC and TG tract cyst?
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TG cyst ---> midline of neck
BCC ----> side of neck |
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What is this?
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White sponge nevus
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Dx?
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Gingival cyst of infant
This can have multiple keratin site |
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one or more teeth shows immature mineralization, so looks pale on radiograph. which is this?
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Ghost teeth
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Dx?
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Median rhomboid glossitis
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65 yo Pt under multiple myeloma tx
Dx? |
Osteonecrosis
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Ectodermal Dysplasia has Xerostomia?
|
YES
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Which syndromes have microdontia?
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Down syndrome and Pituitary dwarfism
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Which syndromes have macrodontia?
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Pituitary gigantism and XYY males
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Dens in dente 's preference MX or MN?
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Mx
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Enamel pearl
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Occurs on the roots at the furcation area
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3 type AI?
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Hypoplasitc
Hypomaturation Hypocalcified amelogenesis imperfecta can be inherited all kinds of way. AD or AR or X-linked |
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Turner's tooth
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A permanent tooth showing hypoplasia resulting from injury or inflammation of the precedent primary tooth
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List 3 developmental oral white lesion?
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White sponge nevus
Leukoedema Hairy tongue |
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Hairy tongue is infectious white lesion [T/F]
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False
Developmental |
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Is white sponege nevus bilateral?
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Yes
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Is linea alba is congenital?
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No, it is a reactive white lesion
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