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13 Cards in this Set

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A/w Gardner's Syndrome (APC - small and large polyps, soft tissue tumors, desmoid tumors)
Osteomas
A male <25 years comes in complaining of nocturnal pain just below the kneecap. PE shows a hard mass. Biopsy shows interlacing trabeculae of woven bone surrounded by osteoblasts. Dx?
Osteoid osteoma

Tx?
excision

(do NOT radiate, it will cause malignancy)
A male <25 years comes in complaining of nocturnal pain in lower back. PE shows a large, hard mass. Biopsy shows interlacing trabeculae of woven bone surrounded by osteoblasts. Dx?
Osteoblastoma
Bone tumor that occurs most often in females?
Giant Cell tumor aka osteoclastoma

"double bubble" or soap bubble
MC primary Bone tumor
Osteochondroma

originates from...
long metaphysis
Biopsy shows mature bone with a cartilaginous cap.
osteochondroma

peak incidence?
less than 25
benign cartilaginous neoplasm found in intramedullary bone, involving hands, feet, and distal extremities
enchondroma
Anaplastic small blue cell malignant tumor, aggressive with early metastasis
ewings
(but responds to chemo)

bx?

gene?
onion skin appearance

11:22 translocation
11:22 translocation
Ewings Sarcoma

mc common in ....
boys <15 yo
expansile glistening mass withing the medullary cavity
chondrosarcoma

mc in...

located...
men 30-60


in pelvis, spine, humerus, tibia or gemur
mc malignant tumor of bone
malignant myeloma

2nd mc?
osteosarcoma (codman's triangle)
"Codman's triangle"?
osteosarcoma

mc in...
location?
men 10-20 yo

metaphysis of long bones around distal femur and proximal tibia
17 yo males presents with pain around right knee. PMHx is (+) of familial retinoblastoma. Lab studies show and elevated alkaline phosphatase, dx?
osteosarcoma
(rf: familial rb, pagets, radiation)

What would an x ray show?
"Codman's triangle" in metaphysis of bone