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7 Cards in this Set

  • Front
  • Back
Psoriasiform epidermal hyperplasia: characteristics
- Regular elongation of rete ridges
- Thickening (clubbing) of their lower portions
- Parakeratosis
- Collections of neutrophils
- Papillary edema
- Tortuous capillaries (accounts for Ausptiz sign)
Psoriasis vulgaris: histopath
- Psoriasiform hyperplasia
- Regular elongation of rete ridges
- Clubbing
- Confluent parakeratosis
- Hypogranulosis
- Collection of neutrophils (Munro, Kogoj)
What diseases exhibit psoriasiform dermatitis?
- Psoriasis and variants
- Reiter's syndrome (type of seronegative spondyloarthropathy, can't climb a tree, see, pee)
- Lichen simplex chronicus
- Mycosis fungoides
- Pityriasis rosea
Lichen planus: histopath
- hyperkeratosis
- Hypergranulosis (wedge-shaped)
- Irregular hyperplasia
(saw-tooth pattern)
- Band of mononuclear infiltrate obscuring the DE junction.
- Vacuolization of the basal layer
- See IgM positive pink, dead leukocytes
- apoptotic keratinocytes
What diseases can exhibit spongiosis?
- Allergic contact dermatitis
- Arthropod bites
- Atopic dermatitis
- Dermatophytoses
- Drug reactions
Spongiosis: histopath
- Vesicles
- Dermal edema
- Eosinophils
Urticaria and angioedema: histopath
- Epidermis is usually unremarkable
- Sparse superficial perivascular mixed lymphocytic and eosinophilic infiltrate
- Mild telangiectasia and dermal edema