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64 Cards in this Set
- Front
- Back
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fragmentation of cell nucleus/chromatin
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karyorrhexis
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nuclear changes
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coagulation necrosis
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chromatin clumping
condensation/shrinking of cell nucleus |
pyknosis
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fading of chromatin
destruction/dissolution of nucleus |
karyolysis
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condensation of chromatin
shrinkage of nucleus |
karyopyknosis
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fragmentation of chromatin
fragmentation of nucleus |
karyorrhexis
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nuclear changes are morphologic hallmarks of
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irreversible cell injury
necrosis |
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acute/early stage inflammation
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neutrophils
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PMN=
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neutrophils
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most numerous of WBC
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neutrophils
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chemotactic for neutrophils
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C3a
C5a |
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anaphylatoxins
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C3a
C5a |
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BV :
dilation hypotension increased vascular permeability |
anaphylatoxins
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process of attracting
recruiting cells |
chemotaxis
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cell moves toward a higher concentration of a chemical substance
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chemotaxis
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abnormal sac containing air/fluid
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cyst
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lined by epithelium
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cyst
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tumor a/w ulcerated infections
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granuloma
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modified macrophage
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epitheliod cell
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found in granulomas
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epithelioid cell
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surround the nodule of epithelioid cells
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lymphocytes
plasma cells fibroblasts |
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growth of tissue
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tumor
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abnormal regulation of cell division
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tumor
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necrosis with putrefaction
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gas gangrene
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putrefaction
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rotting
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toxin that damages cell membranes
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alpha toxin
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lecithinase
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alpha toxin
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hemolysis from
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alpha toxin> damage RBC membrane>hemolysis
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ischemia>
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coagulation necrosis
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cell death within a living body
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necrosis
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suppuration
abscess ischemic injury to CNS |
liquefaction necrosis
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typical of TB
granulomatous inflammation |
caseous necrosis
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immune mediated vascular damage
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fibrinoid necrosis
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injured pancreas
trauma to adipose tissue |
fat necrosis
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brain/spinal cord
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liquefaction necrosis
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inflammation with
epithelioid macrophages |
granulomatous
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a/w granulomatous inflammation
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infectious agents
sarcoidosis crohn |
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mycobacterial
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TB
leprosy |
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granulomas produced by
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multinucleated giant cells
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langerhans
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multinucleated giant cells
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granulomatous inflammation a/w
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caseous necrosis
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caseous necrosis produced by
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mycobacterium TB
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subtype of chronic inflammation
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granulomatous inflammation
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epitheliod cells
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nodular collections of specialized macrophages
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cells involved with acute inflammation
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basophils
platelets tissue mast cells |
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appear later in cellular phase
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macrophage
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transition btw
-acute -chronic inflammation |
macrophages
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vascular response
cellular response |
acute inflammation
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increased vascular permeability
leukocytic cellular infiltration repair |
acute inflammation
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systemic signs of acute inflammation
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fever
tachycardia leukocytosis (neutrophils) |
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exudate
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straw
pus |
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principally water
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exudate
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increased intravascular hydrostatic pressure
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transudate
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non inflammatory conditions
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transudate
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acute inflammation rxn
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neutrophils
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tissue necrosis
proteolytic enzymes WBC |
suppurative
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contains
few blood cells low protein content low specific gravity |
transudate
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granulocytes in neutrophils
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acute cellular phase of acute inflammation
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predominated cellular phase in acute inflammation
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PMN
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later in cellular phase
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macrophage
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parasitic rxn
allergic rxn> |
eosinophils
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vasoconstriction>
vasodilation> increased vascular permeability |
vascular phase of acute inflammation
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first defense cell to migrate to injured tissue
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by chemotaxis>
leukocytes |
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leukocytes engulf particulate matter by phagocytosis
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cellular phase of acute inflammation
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