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10 Cards in this Set
- Front
- Back
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Naltrexone |
mu opioid receptor antagonist decreases craving and blocks rewarding effect of alcohol intake used to prevent relapse in opioid addicts |
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acamprosate |
analogue of GABA decreases cravings and blocks rewarding effects of alcohol intake |
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disulfiram |
inhibits activity of aldehyde dehydrogenase alcohol is metabolized to acetaldehyde by alcohol dehydrogenase the that acetaldehyde is meetabolized by the aldehyse dehydrogenase into acetic acid and acylCoA. so inhibition of ALDH increases levels of acetaldehyde
consumption of alcohol during this treatment can severe facial flushing increased body temp vomiting vertigo blurred vision confusion |
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nicotine replacement |
decreases craving |
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varenicline |
nicotine receptor alpha 4 beta 2 partial agonist decreases craving and blocks rewarding effects of nicotine |
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bupropion |
binds to dopamine uptake transporter and helps alleviate depressed mood observed during nicotine withdrawl blocks nicotinic receptors and decreases rewarding effects of nicotine |
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methadone |
long acting mu opioid receptor agonist that helps in attenuating the acute aversion withdrawl effects of opioid decreases craving |
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buprenorphine |
partial mu agonsit and can help in minimizing aversion effects of opioids decreases craving |
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suboxone |
its buprenorphine and nalaxone nalaxone is not orally effective but its combined to prevent intravenous abuse of buprenorphine |
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naloxone |
mu antagonist not orally effective used to treat opioid intoxication |
