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65 Cards in this Set

  • Front
  • Back

Arteries

(Elastic and contractile, walls are thick) Carry blood away from heart

Arterioles

Smaller in diameter; important in regulation of blood pressure; delivers blood to capillaries

Capillaries

Microscopic vessels that connect arterioles to venules; permits exchange of gas nutrients and waste between blood and tissues; critical for homeostasis, main site of cardiovascular activity

Venules

Small veins formed from the union of capillaries; they collect capillary blood and leads to veins

Veins

Carry blood to heart

Tunica externa (tunica adventitia)

(Thickest) Elastic and collagen fibers; stabilize and anchor blood vessels in surrounding tissue; top layer of vein

Tunica media (middle)

Collagen fibers, elastic and smooth muscle fibers (external elastic membrane) middle layer of vein

Tunica interna (tunica intima - inner)

Endothelium and basement membrane (internal elastic membrane) thinner than arteries; bottom layer of vein

Artery walls are _____ than veins

Thicker

Artery tunica media contains more _____&_____ than veins do

Smooth muscle and elastic fibers

What do artery walls do when they aren't being opposed by blood pressure?

Recoil

Veins contain valves to prevent____?

Backflow of blood

Elastic arteries (conducting arteries)

Nearest the heart, largest diameter, help propel blood from heart when ventricles are relaxing, helps maintain blood pressure

Muscular arteries (distributing arteries)

Medium-sized arteries, greater vasoconstriction and vasodilation, distribute blood to body, pressure points to reduce bleeding

Arteriosclerosis

Thickening and toughening of arterial walls

Focal calcification

Calcium salts deposited in tunica media, limbs and genital organs

Atherosclerosis

Formation of lipid deposits in tunica media

Arteriosclerosis factors

Lipid levels, cholesterol, smoking, hypertension, high LDL, diabetes, obesity, stress

Arteriosclerosis results

Plaque formation and can lead to blood clots

Vasoconstriction

Deceased blood flow, increased blood pressure

Vasodilation

Increased blood flow, decreased blood pressure

What are the 3 types of capillaries

Continuous, fenestrated, and sinusoid

Continuous capillaries

Endothelium complete, found in all tissues except cartilage and epithelia, permit diffusion of water, small solutes, lipid soluble materials, prevent loss of blood and plasma protein

Fenestrated capillaries

Pore-containing capillaries, allow rapid exchange of water and solute between blood plasma and IF

Sinusoid capillaries

Capillaries with gaps between cells, permits free exchange of large solutes and water between blood and IF

Capillary beds

Interconnected = 1 arteriole connected to dozens of capillaries

Capillary exchange

Movement of substances between blood plasma and interstial fluid

Diffusion

Movement of a substance down its concentration gradient (high to low)

Transcytosis

Substances enter endothelium by endocytosis, move across cell and leave by exocytosis

Bulk flow

Passive process where large numbers of ions, molecules or particles move together in the same direction (high pressure to low pressure)

Filtration

Pressure-driven movement of fluid and solutes from capillaries into interstitial fluid

Reabsorbtion

Pressure-driven movement from interstitial fluid into blood capillaries

Venuos valves

Venous bp is low and can't overcome force of gravity, valves prevent blood backflow in veins, push blood to heart to improve venous return

Venous return

Volume of blood flowing back to the heart

Skeletal muscle pump

Standing/rest proximal valve closet to heart and distal valve are open; blood flows toward heart (leg muscle contraction compresses vein which pushes blood through proximal valve, distal valve closes, after muscle relaxation proximal valve closes and distal vein opens

Respiratory pump

Alternating compression and decompression of veins during respiration

What happens if venous vein malfunctions (stretch/weaken)?

Blood pools in veins and vessel distends

2 types of venous valve malfunction

Varicose veins and hemorrhoids

Edema

Filtration greatly exceeds reabsorbtion

Blood flow

Volume of blood that flows through any tissue in a given period of time

Cardiac output (co)

Co= hr x sv

What determines capillary blood flow?

Pressure (P) and resistance (R)

What must the heart do to keep blood flowing?

Generate pressure to overcome resistance to blood flow in circuits

Flow is proportional to___?

Pressure

Flow is inversely proportional to___?

Resistance

Higher blood viscosity from?

Dehydration or polycythemia

Lower blood Viscosity from?

Anemia or hemorrhage

Mabp

Perfusion pressure in organs

Hypotension

BP is to low

What are the 3 major mechanisms for control of bp?

Autoregulation, neural mechanism, and endocrine mechanism

Autoregulation

Ability of tissue to adjust blood flow to match metabolic needs in localized area

Neural mechanism

Cardiovascular centers found in medulla oblongota

Baroreceptor reflex

Pressure-sensitive sensory receptors in carotid arteries

Chemoreceptor reflexes

Monitor chemical composition of blood

Endocrine mechanism

Hormones that increase bp, provides short term and long term regulation of cardiovascular performance

Epinephrine and norepinephrine

Stimulate cardiac output and peripheral vasoconstriction

Epo

Increase in rbc's leads to increase in bp

Antidiuretic hormone (ADH)

Increase blood volume

Angiotension 2

Responds to decreased pressure at kidneys

Atrial natriuretic peptide (ANP)

Produced by cardiac muscle cells in right atrium wall in response to excessive stretching during diastole

Histamine

Causes vasodilation of arterioles

What is cardiac output at rest?

5.8liters/min

Maximum level of cardiac output during heavy exercise is ____?

20-25L/min

Shock

Failure of cardiovascular center to deliver enough oxygen and nutrients to meet metabolic needs of cells/tissues

In a capillary bed the bands of smooth muscle at the entrance to each capillary is called a

Precapillary sphincter