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28 Cards in this Set

  • Front
  • Back

CHARACTERISTIC OF WHOLE BLOOD

38 degrees Celsius


5x viscous than water


PH- 7.35-7.45


5 liters

PLASMA

46-63% of blood


92% Water


8% solutes

PLASMA PROTEINS

Albumins


Globulins


Fibrinogen


Hormones

PLASMA SOLUTES

Electrolytes


Organic Nutrients


Waste Products

ERYTHROCYTES (Red blood cells)

Most common formed element


40-54% of whole blood


Carry oxygen

STRUCTURES of RBC'S

Hemoglobin


Anucleated


Biconcave


Degenerates in about 120 days

HEMOGLOBIN


Give RBC'S color


Globular protein


95% of intercellular proteins


Range- 12-18

STRUCTURE OF HEMOGLOBIN

4 polypeptide chains


4 iron heme groups

RBC life span and circulation

HEMOPOIESIS- production of blood cells

HEMOCYTOBLASTS

Stem cell in red bone marrow

ERYTHROPIESIS

Production of new RBC'S

RBC'S

Replaced at a rate of 3 million per second

RBC'S (damaged)

Old/damaged are phagocytized by macrophages

RBC'S (damaged)

Could lyse and release Hb

ERYTHROPIESIS

Occurs in red bone marrow

ERYTHROPIESIS

Controlled by EPO


Secreted by the kidney

Increased EPO secretion

Anemia


High altitude


Lung damage


Aerobic activities

LEUKOCYTES

6000-9000


Have nuclei


Granular


Aganulocyte

NEUTROPHILS

Granular


Most common type


Faint staining granules


Killed by Phagocytosis

EOSINOPHILS

Red staining granules


2-4%


Parasites


Kills by release of cytotoxic and Phagocytosis

BASOPHILS

Dark staining granules


Contains histamine and heparin

MONOCYTES

Largest WBC'S


NO granules


Large nucleus

LYMPHOCYTES

2nd most common


Nucleus takes up most of the cell


Directs immune response

LEUKOCYTOSIS

Increased WBC count

LEUKOPENIA

Low WBC count

HEMOCYTOBLASTS


Two stem cells

HEMOCYTOBLASTS



MYELOID STEM CELL

Most WBC


CSF are released by WBC'S when over worked

HEMOCYTOBLASTS



LYMPHOID CELLS

Production stimulated during immune response


Occurs in lymphoid tissue