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129 Cards in this Set

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Actinobacillus ligneresii
CATTLE

Wooden Tongue

GM- Bacilli; fac. Anaerobe

COMMENSAL- oral cavity or rumen
Actinomycese bovis
CATTLE

Lumpy Jaw

GM+ branching filaments;

COMMENSAL MM in oral cavity and DT in animals
Fusobacterium Necrophorum
CALF- DIPHTHERIA- oral(foul odor; necrotic material in cheek, FAD);and laryngeal necrobacillosis (less common- lesions in larynx; inflammed and edematous; moist painful cough & swallowing, FAD, salivation, rancid foul breath)

SWINE- BULLNOSE (necrotic rhinitis; cellutis of soft tissues of nose and face)

GM- bacilli; long non-branching filaments; obligate anaerobe;

COMMENSAL MM and Common inhabitant in env. of cattle
Mycobacterium avium ssp. paratuberculosis
CATTLE & SHEEP & GOATS - Johne's Disease (granulomatous Dz in GI of ruminants; chronic wt. loss & severe DIARRHEA; longer calving intervals; malabsorption & hypoproteinemia) (Diarrhea less severe in S & G's)

GM+ bacilli; acid fast; strict aerobe

Found in intestinal tract of infected animals (shed in milk ad colostrum); can survive in soil; spread by ingestion of contaminated feces, milk, or colostrum

??ZOONOTIC?? (not proven) see note
MAY be a cause of CROHN's Dz in humans if organism is not killed by pasteurization of milk
Bovine Viral Diarrhea
CATTLE (2mos-2yrs)

DIARRHEA (Death in calves)

Flavivirus (ENV, +RNA)
genus: Pestivirus
Rhinderpest
CATTLE, SHEEP & GOATS,

DIARRHEA; fever, lymphopenia nasal and lacrimal discharges

Paramyxovirus (ENV, -RNA)
genus: morbilivirus

high mortalitiy and morbidity

NOT IN US
Rotavirus
CATTLE (1-3wks)- White scours
GOATS & SHEEP, PIGS, HORSES & CATS(1-8wks)- Diarrhea
CHICKENS & TURKEYS (<5wks)- watery droppings

Reovirus (non-ENV; dsRNA)
genus: Rotavirus

Can be isolated from healthy animals (RT and/or GI)
Malignant Catarrhal Fever
CATTLE

FATAL RESP. Dz (gen. lymphadenopathy, CNS signs, BILATERAL OPTHALMIA (corneal opacity starts in center and moves to periphery**imp diagnostic sign); Death in a week

gamma Herpesvirus (ENV; dsDNA; intranuclear inclusions)

feedlots in N.America- very contagious among cattle
Enterotoxigenic Escherichia coli
CATTLE(<1wk)- severe diarrhea full of gas bubbles

SHEEP & GOATS(<1wk)- diarrhea/depression

PIGS(neonatal- profuse yellow watery diarrhea); (Post-weaning- watery diarrhea, FAD)

PUPPIES(watery diarrhea)

GM- bacilli, fac. anaerobe

COMMENSAL of intestines of Humans and animals, SOIL, WATER, and on PLANTS

GM- bacilli

fac. anaerobe
Necrotoxigenic Escherichia coli
CALVES-hemorrhagic colitis with ulcerative inflamm. lesions in colon--> sometimes get septecemic Dz.

PIGS- starts as ENTERITIS--> ENTEROCOLITIS(blood stained diarrhea & bacterimic spread to lungs is common)

GM- bacilli, fac. anaerobe

COMMENSAL of intestines of Humans and animals, SOIL, WATER, and on PLANTS


ZOONOTIC
Shiga-toxin prod. Escherichia coli & Enterohemmorhagic e.coli
CALVES (1-8wks)- enteritis and mucoid hemorrhagic diarrhea (dehydration, weakness, and depressed growth rate)death w/in 24-48hrs.
older CATTLE- acute enteritis--> FAD, (diarrhea may contain blood, usually mucus)

PIGS(recent post-weaning)- EDEMA Dz, diarrhea

GM+ bacilli; fac. anaerobe

ZOONOTIC
Salmonella enterica
CATTLE, HORSES, SWINE, DOGS, CATS, CHICKENS & TURKEYS
septicemic Dz in newborns with fever, depression, and death w/in 24-48hrs;
Older animals: FAD, fluid diarrhea (usually w/mucus sometimes blood); occ. abd pain and tenesmus.

GM- bacilli; fac. anaerobe
non-lactose fermenting

ZOONOTIC
Clostridium perfringens
CALVES (<10days)-enterotoxemia (diarrhea, dysentery, acute abd. pain and aimless running. ng enteritis; diarrhea; etc.

GM+ bacilli; spore forming
most are obilgate anaerobes (some can be aerotolerant)
Bovine Coronavirus
CATTLE-(1-4wks)- Neonatal scours (anorexia, liquid yellow diarrhea(4-5days)

Coronavirus (ENV, +RNA, HA)
Dichelobacter nodosus
SHEEP or GOATS

FOOT ROT- (soaking of foot)

GM- bacilli

obligate anaerobe
Fusobacterium necrophorum
CATTLE

FOOT ROT- (damage, necrotizing cellulitis; lameness)

GM- bacilli; long non-branching filaments;
obligate anaerobe

COMMENSALS of MM, fecal flora
Staphylococcus intermedius
DOGS

PYODERMA (pus)

GM+ cocci (clusters);
fac. anaerobe; grows best aerobically
COAG +

COMMENSAL MM
Staphylococcus hyicus
PIGS

GREASY PIG (exudative epidermititus)

GM+ cocci (pair, short chains, or clusters)
fac. anaerobe, grows best aerobically
COAG +

COMMENSAL Skin,nasal mucosa, conjunctive, vagina
(trauma)
Streptococcus canis
DOGS

NECROTIZING FASCIITIS & TOXIC SHOCK-LIKE SYNDROME

GM+ cocci; non-spore forming;
(pairs or chains); aerotolerant anaerobe
GROUP G

COMMENSAL MM of URT, DT, and lower Genital tract
Erysipelothrix rhusiopathiae
SWINE- DIAMOND SKIN DISEASE or septicemia

SHEEP- POLYARTHRITIS

TURKEYS- Bacterimic- cyanotic skin, droopy, unsteady, may die

GM+ slender bacilli; fac. anaerobe; facultative intracellular parasites

COMMENSAL OF ALT & Lymph tissues (tonsils); also slime of fish

ZOONOTIC- erysipeloid
Erysipelothrix tonsillarum
DOGS

VALVULAR ENDOCARDITIS and ARTHRITIS

GM+ slender bacilli; fac. anaerobe; facultative intracellular parasites

COMMENSAL OF ALT & Lymph tissues (tonsils); also slime of fish
Corynebacterium Pseudotuberculosis
SHEEP & GOATS- CASEOUS LYMPHADENITIS (thick green pus)

CATTLE & HORSES- ULCERATIVE LYMPHANGITIS (lower limbs)(creamy green pus)

GM+ diphtheroid; fac. anaerobe

COMMENSAL MM, skin, ALT (also found in soil where these animals live) (need breaks in skin)
Clostridium septicum
CATTLE, HORSES, PIGS, SHEEP & GOATS, CHICKENS & TURKEYS

MALIGNANT EDEMA

BRAXY (FATAL)- SHEEP

GM+; bacilli; spore-forming; anaerobic

SOILS WW & Intestines of animals and humans
Clostridium novyi
CATTLE- TYPE B strain- Black Dz (necrotic hepatitis)- death w/in 2 days

RAMS- TYPE A strain- BIGHEAD- Toxic endothelial damage--> edema of head, neck and thorax (death w/in 2 days)

GM+; bacilli; spore-forming; anaerobic

SOILS WW & Intestines of herbivores
Clostridium haemolyticum
CATTLE & sheep- (C. novyi TYPE D)- REDWATER Dz (bacillary hemoglobinuria; FA; agalactia; icteric mm; rapid death)

GM+; bacilli; spore-forming; anaerobic

SOILS WW, ruminant DT & liver
Clostridium chauvoei
CATTLE

BLACKLEG (emphysematous necrotizing myositis)- endogenous (or ingestion or injury) only seen in cattle

GM+; bacilli; spore-forming; anaerobic

SOILS WW & Intestines, liver and other tissues of animals
Clostridium sordelli
CATTLE, HORSES, SHEEP & GOATS

ALONE causes- fatal myositis & hepatic Dz
In wound infections- assoc. with other C. species

GM+; bacilli; spore-forming; anaerobic
Mycobacterium Lepraemurium
CATS

FELINE LEPROSY (chronic noduloulcerative infection of skin; granulomas; painless)

GM+ bacilli; acid fast; aerobic

Bites of contact with INFECTED RATS
Dermatophilus congolensis
CATTLE- Crusts and scaps

HORSES- RAIN ROT

SHEEP & GOATS- STRAWBERRY FOOTROT & LUMPY WOOL

GM+ braching filamentous rods;
dimorphic, having branched filamentous "mycelia" with motile "zoospores (look like GM+ cocci)"
fac. anaerobe

Found on infected animals
Micosporum canis
CATS- often subclinical, (noninflamm.)

DOGS- scaly, alopecic patches

Dermatophyte- keratinophilic molds causing RINGWORM

RESEVOIR- CATS

ZOONOTIC
Microsporum nanum
PIGS- tannish, crusty lesions (trunk), painless, margins slightly inflammed

Dermatophyte- keratinophilic molds causing RINGWORM

RESEVOIR- SOIL

ZOONOTIC
Microsporum gallinae
CHICKENS & TURKEYS- whitish chalky scaling on combs & wattles

Dermatophyte- keratinophilic molds causing RINGWORM

RESEVOIR- Chicken & Turkeys

ZOONOTIC
Microsporum gypseum
CANINE- spreading, scaling to inflamm. lesions, suppuration

HORSES- suppurative under alopecic thickened areas

Dermatophyte- keratinophilic molds causing RINGWORM

RESEVOIR- SOIL

ZOONOTIC
Trichophyton mentagrphytes
DOGS & CATS- spreading, scaling to inflamm. lesions, secondary suppuration

Dermatophyte- keratinophilic molds causing RINGWORM

RESEVOIR- RODENTS

ZOONOTIC
Trichophyton verrucosum
CATTLE- painless think white placques, local alopecia

Dermatophyte- keratinophilic molds causing RINGWORM

RESEVOIR- CATTLE

ZOONOTIC
Trichophyton equinum
HORSES- dry scaly noninflamm. lesions, sore to touch

Dermatophyte- keratinophilic molds causing RINGWORM

RESEVOIR- HORSES

ZOONOTIC
Malassezia pachydermatis
DOGS

DERMATITIS- otitis externa; seborrhea, alopecia, excoriationw/ erythema, lichenification, hyperpigmentation, pruritis.

SMALL BUDDING YEASTS (LIPOPHILLIC!!)

Colonize skin and mucocutaneous regions of healthy mammals. Infections ENDOGENOUS

Infection occurs due to increase lipids & moisture and compromised stratum corneum.
Atypical Mycobacterium
M. fortuitum
M. smegmatis
M. chelonae
CATS- ulcerative lesions

GM+ bacilli; acid fast; aerobic

Bites or contact with RATS
Sporothrix schenkii
HORSES- ULCERATIVE LYMPANGITITS (pyogranulomatous)

dimorphic saprophytic fungi; saprophytic form- mold w/ septate mycelium; conidia formed on conidiophores;
pathogenic form- (in tissues) budding pleimorphic yeasts

FOUND IN ENVIRONMENT (plant material and soil WW)
Histoplasma capsulatum var. faciminosum
HORSES- ULCERATIVE LYMPHANGITIS (pyogranulomatous)(epizootic- chronic contagious Dz)

Dimorphic fungus- mold when saprophytic; budding yeast in tissues

Enter via wounds and abrasions
(NONENDEMIC areas- infected are culled)
Streptobacillus moniliformis
HUMANS- RAT BITE FEVER (systemic; polyarthritis or synovitis; may be fatal)

GM- pleomorphic bacillus; fac. anaerobe

COMMENSAL of URT of RAT and other rodents
Bartonella henselae
HUMANS- CAT SCRATCH Dz

GM- bacilli; aerobic

Natural intraerythrocytic parasites of CATS (transmitted b/w cats thru fleas)
Clostridium difficle
FOALS- NECROTIZING ENTEROCOLITIS- SEVERE DIARRHEA (may contain blood)

DOGS- Chronic diarrhea (may contain blood)

GM+ bacilli; spore forming; most are obligate anaerobes, but can be aerotolerant

COMMENSAL GI of healthy and sick animals; Dz due to ENDOGENOUS infection (stress)
Clostridium piliforme
FOALS, DOGS, MICE- TYZZER'S Dz (Lethargy, depression, anorexia, abd. discomfort & distension, hepatomegaly; death w/in 24-48hrs)

GM+ bacilli; spore forming; most are obligate anaerobes, but can be aerotolerant

obligate intracellular pathogen (grows in hepatocytes); commensal in intestinal tract--> invades liver via lymphatics & blood vessels after host is stressed
Prototheca zopfii
DOGS- COLITIS (bloody diarrhea, wt. loss, OCULAR involvement-red painful eyes & blindness, cloudy bilaterally)

(usually only in IMMUNOSUPPRESSED or IMMUNOCOMPROMISED animals)

Saprophytic achlorophyllus algae

UBIQUITOUS IN NATURE
Campylobacter jejuni, C. coli
DOGS, CATS- FEBRILE ENTERITIS (often assymp.)

GM- curved bacilli; microaerophillic

COMMENSAL GI of mammals and birds

ZOONOTIC (raw milk and poultry)

most common cause of gastroenteritis in humans in US
Lawsonia intracellularis
PIGS- PROLIFERATIVE ENTEROPATHY (post-weaned (6-20wks), dz is chronic) (anorexia, dullness, apathy, sometimes irregular diarrhea, wt. loss.
(4-12mos) less commonly--> acute hemorrhagic anemia (prod. of black tarry feces, die w/o any signs)

OBLIGATE INTRACELLULAR (epithelial cells) GM- curved bacilli

COMMENSAL Intestinal tract of swine
Brachyspira hyodysenteriae
PIGS- SWINE DYSENTERY (diarrhea due to inflamm. response)

GM- (thin); O2 tolerant anaerobes; SPIROCHETES (loosly coiled); axial filaments b/w their inner and outer membranes for motility

In GI of animals that have Dz or have recently recovered from the Dz
Mannheimia haemolytica
CATTLE- SHIPPING FEVER (fibrinous pleuropneumonia or bronchopneumonia);(fever, inapp, listlessness, dyspnea, coughing, mucopurulent nasal discharge, crusty nose, ocular discharge, abnormal lung sounds)

SHEEP & GOATS- SECONDARY PNEUMONIA (similar signs as Shipping Fever in Cattle)

GM- coccobacilli (bipolar); fac. anaerobe; capsule;
stain like saftey pin

Freq. inhabitant of nasopharynx; infections usually ENDOGENOUS due to STRESSORS
Pasteurella multocida
CATTLE, SWINE, SHEEP & GOATS- secondary invader to other bac or viruses and causes PNEUMONIA (acute infections- dyspnea, prostration, high fever); (subacute- cough, abd. breathing, and decreased wt. gain)

SWINE- in conjunction w/ Bordetella brochiseptica- ATROPHIC RHINITIS (disappearance of nasal turbinates; sneezing, epistaxix, distortion of facial structure)

RABBITS- SNUFFLES (mucopurulent rhinitis; conjunctivitis; lethargic, anorexic)

GM- coccobacilli (bipolar); fac. anaerobe; capsule;
stain like saftey pin

COMMENSAL URT & GI of variety of animals (most infections

ZOONOTIC
Actinobacillus equuli
FOALS- septicemia, maybe pneumonia as well

GM- sm. bacilli or coccobacilli; fac. anaerobe

COMMENSAL OF Mucosal surfaces
Actinobacillus pleuopneumoniae
PIGS- SEVERE FIBRINOUS PLEUROPNEUMONIA (acute- fever, apathy, inapp, resp. distress w/ dyspnea, cough)
(chronic- intermittent cough, not really gaining wt., dec. appetite, excercise intolerant)

GM- sm. bacilli or coccobacilli; fac. anaerobe

COMMENSAL of Mucosal surfaces
Haemophilus parasuis
PIGS- BRONCHOPNEUMONIA secondary to viral infection

GM- bacilli or filaments; fac. anaerobe

COMMENSAL of NASOPHARYNX of swine
Avibacterium paragallinarum
CHICKENS- INFECTIOUS CORYZA (nasal discharge, facial swelling, lacrimation, anorexia, diarrhea, decreased food and water consumption; dec. wt. gain and egg prod)

GM- bacilli or filaments; fac. anaerobe

COMMENSAL URT of sick animals or those recovering from illness
Histophilus somni
CATTLE- PNEUMONIA (usually in animals coinfected w/ M. haemolytica) & NEURO Dz (thrombo menigoencephalitis)

GM- bacilli; fac. anaerobe

Persists at mucosal sites in diseased and subclin. animals
Bordetella bronchiseptica
PIGS- Non-progressive ATROPHIC RHINITIS (sneezing, snuffling, & mucopurulent discharge)

DOGS- KENNEL COUGH (usually assoc. w/ concurrent viral infection (adeno or parainfluenza) (paroxysmal coughing, retching, expectoration of mucus)

GM- bacilli or coccobacilli; aerobic

Found in URT of dogs, cats, swine, rabbits, horses, rats and g. pigs
Bordetella avium
TURKEYS- TURKEY CORYZA (young poults; sinusitis, tracheitis, bronchopneumonia, and airsacculitis--> sneezing, nasal exudate, conjunctivitis, tracheal rales, dyspnea, dec. activity & feeding, huddling)

GM- bacilli or coccobacilli; aerobic

Found in URT of dogs, cats, swine, rabbits, horses, rats and g. pigs
Avian Escherichia coli
CHICKEN & TURKEYS- secondary invader in birds after viral or mycoplasma resp. Dz- AIRSACCULITIS

GM- bacilli; fac. anaerobe

COMMENSAL of lower GI; can also colonize pharynx and trachea; abundant in env. inhabited by animals.
Chlamydophila psittaci
YOUNG PSITTACINE birds- don't feed, mucopurulent nasal discharge, copious ocular exudate, yellowish-green diarrhea; birds die of dehydration and emaciation

TURKEYS- inapp, wt. loss, red. egg prod., greenish-yellow gelatinous droppings; infection starts in resp. tract--> AIRSACCULITIS and PNEUMONIA

GM-, replicate by binary fission

Found in resp, intestinal, and genital tracts of mammals and birds

ZOONOTIC
Streptococcus equi ssp. equi
HORSES- STRANGLES (contagious rhinopharyngitis; FAD, serous nasal discharge--> copius and purulent; severe pharyngitis and laryngitis often seen; head may be extended due to relieve pain in throat--> abcesses in regional LN.

GM+ cocci (pairs or chains); non-spore forming; most are aerotolerant (some strict anaerobes)

MM in URT, Lower genital tract, and DT.
Streptococcus equi ssp. zooepidemicus
HORSES- SECONDARY PNEUMONIA


GM+ cocci (pairs or chains); non-spore forming; most are aerotolerant (some strict anaerobes)

MM in URT, Lower genital tract, and DT.
Streptococcus canis
CATS- CERVICAL LYMPHADENITIS, PHARYNGITIS, and TONSILLITIS (fever, anorexia, coughing and dyspnea)


GM+ cocci (pairs or chains); non-spore forming; most are aerotolerant (some strict anaerobes)

COMMENSAL IN DOGS
Streptococcus suis
PIGS- PNEUMONIA


GM+ cocci (pairs or chains); non-spore forming; most are aerotolerant (some strict anaerobes)

MM in URT, Lower genital tract, and DT.
Rhodococcus equi
FOALS (1-5mos)- SUPPURATIVE BRONCHOPNEUMONIA (large abcesses in lungs and bronchial LN; fever, inc. RR, cough, nasal discharge, depression)

GM+ encapsulated bacilli or cocci; strict aerobe; variably acid-fast

SOIL and ANIMAL MANURE

ZOONOTIC in Immunocompromised people (pyogranulomatous pneumonia)
Mycobacterium bovis
CATTLE- PULMONARY TUBERCULOSIS (Acute- extensive necrosis in lungs)
(Chronic- coughing, progressive emaciation, erratic appetite, low grade fever) (Host can harbour organism in granulomatous lesions, which can reactivate if host is immune suppressed)

GM+ bacilli; acid-fact; strict aerobe

Found in animals with TB

ZOONOTIC thru unpasteurized milk--> hunchback
Mycobacterium avium ssp. avium
CHICKENS- TUBERCULOSIS (infection usually via alimentary canal but pulmonary involvement is common)

GM+ bacilli; acid-fact; strict aerobe

Found in animals with TB

ZOONOTIC--> severly immunocompromised humans (AIDS)
Nocardia asteroides & Nocardia nova
DOGS- NECROTIZING PNEUMONIA with PLEURAL EMPHYSEMA (mucopurulent nasal discharge, anorexia, wt. loss, cough and dyspnea) Usually in animals that are immunosuppressed or immunocompromised

GM+ filamentous bacilli; variably acid fast; strict aerobes

SOIL, WATER, VEGETABLE MATTER
Mycoplasma gallisepticum
CHICKENS & TURKEYS & other BIRDS- CHRONIC RESP TRACT AND AIR SAC Dz (coughing, nasal discharge, tracheal rales, poor growth, dec. egg prod.; SINUSITIS common in TURKEYS)

NO CELL WALL; membranes contain CHOLESTEROL derived from HOST; small pleomorphic cells; fac. anaerobes

MM in URT, DT, and genital tract of hosts they infect
Mycoplasma meleagridis
TURKEYS- mild or inapparent AIRSACCULITIS

NO CELL WALL; membranes contain CHOLESTEROL derived from HOST; small pleomorphic cells; fac. anaerobes

MM in URT, DT, and genital tract of hosts they infect
Mycoplasma mycoides ssp mycoides (small colony type)
CATTLE- CONTAGIOUS BOVINE PLEUROPNEUMONIA (CBPP) range from subclin. to severe acute dz that can be fatal (resp. distress, nasal discharge, reluctance to move; severe symp--> open-mouth breathing with extended neck)

NO CELL WALL; membranes contain CHOLESTEROL derived from HOST; small pleomorphic cells; fac. anaerobes

MM in URT, DT, and genital tract of hosts they infect
Mycoplasma bovis
CATTLE- PNEUMONIA

NO CELL WALL; membranes contain CHOLESTEROL derived from HOST; small pleomorphic cells; fac. anaerobes

MM in URT, DT, and genital tract of hosts they infect
Mycoplasma dispar
CATTLE- BRONCHIOLITIS or ALVEOLITIS

NO CELL WALL; membranes contain CHOLESTEROL derived from HOST; small pleomorphic cells; fac. anaerobes

MM in URT, DT, and genital tract of hosts they infect
Mycoplasma mycoides ssp. mycoides (large colony type)&
Mycoplasma mycoides ssp. capri
GOATS- PLEUROPNEUMONIA that can preceded a rapidly fatal septicemia

NO CELL WALL; membranes contain CHOLESTEROL derived from HOST; small pleomorphic cells; fac. anaerobes

MM in URT, DT, and genital tract of hosts they infect
Mycoplasma capricolum ssp. capripneumoniae
GOATS- CONTAGIOUS CAPRINE PLEUROPNEUMONIA (CCPP) (resp. distress, nasal discharge, reluctance to move)

NO CELL WALL; membranes contain CHOLESTEROL derived from HOST; small pleomorphic cells; fac. anaerobes

MM in URT, DT, and genital tract of hosts they infect
Mycoplasma ovipneumoniae
SHEEP- PNEUMONIA assoc w/ other resp tract paths.

NO CELL WALL; membranes contain CHOLESTEROL derived from HOST; small pleomorphic cells; fac. anaerobes

MM in URT, DT, and genital tract of hosts they infect
Mycoplasma hypopneumoniae
PIGS- WIDESPREAD PNEUMONIC Dz- mild but chronic (nonproductive cough and delayed wt. gain)

NO CELL WALL; membranes contain CHOLESTEROL derived from HOST; small pleomorphic cells; fac. anaerobes

MM in URT, DT, and genital tract of hosts they infect
Mycoplasma felis
EQUINE- SELF-LIMITING PLEURITIS following EXERTION

NO CELL WALL; membranes contain CHOLESTEROL derived from HOST; small pleomorphic cells; fac. anaerobes

MM in URT, DT, and genital tract of hosts they infect
Mycoplasma pulmonis
RATS and MICE- low grade RESP. Dz (wheezing due to purulent nasal exudate & rubbing of eyes and nose)

NO CELL WALL; membranes contain CHOLESTEROL derived from HOST; small pleomorphic cells; fac. anaerobes

MM in URT, DT, and genital tract of hosts they infect
Aspergillus fumigatus and flavus
HORSES- ASPERGILLOSIS (infection of gutteral pouch--> epistaxis, fever, cough, nasal discharge, and inapp.; aquired thru MOLDY HAY)

DOGS- (fumigatus) NASAL ASPERGILLOSIS (profuse nasal discharge, nasal pain, ulceration of external nares, sneezing, may have underlying T or B cell deficiencies)

CHICKENS & TURKEYS (fumigatus)- BROODER PNEUMONIA (after exposure to heavily contaminated feed or litter)(dyspnea, gasping, accelerated breathing, inapp, listlessness, wt. loss; fungal growth in bronchioles and surrounding parenchyma incduces SUPPURATIVE EXUDATE)

MOLDS; septate hyphae; asexual reproductive phialoconidia form on conidiophores

SOIL, VEGETATION, FEED (MOLDY HAY, COMPOST, SILAGE, LITTER)
Moraxella bovis
CATTLE (moreso in young)- PINKEYE (keratoconjunctivitis) (copius watery lacrimation, blepharospasm, and photophobia--> sm. opacity in center--> cover whole cornea--> maybe complete blindness)

GM- coccobacilli (often in pairs; diplobacilli) Aerobes

COMMENSAL on CONJUNCTIVA and URT mucosa in cattle (FACE FLIES trans b/w infected cattle)
Mycoplasma bovoculi
CATTLE- SEROUS DISCHARGE and CONJUNCTIVAL HYPEREMIA (less severe than moraxella bovis; can have concurrent infection with it)

NO CELL WALL; membranes contain CHOLESTEROL derived from HOST; small pleomorphic cells; fac. anaerobes
Chlamydophila pecorum
SHEEP & GOATS- petechial hemorrhages, conjunctival lymphoid follicles and corneal edema--> severe hyperemia, neutrophil infiltrates in cornea and corneal ulcerations

GM- OBLIGATE INTRACELLUAR (can't be seen by gm staining)

In Resp, Intestinal and genital tracts of mammals

ZOONOTIC
OCULAR INFECTIONS IN SMALL RUMINANTS (Sheep & Goats)
Chalmydophila pecorum
Mycoplasma conjunctivae- mild and self-limiting (lacrimation & injected conjunctival vessels; occ. keratitis)
Moraxella (Branhamella)- GM- diplococci; infection usually secondary to C. pecorum or M. conjunctivae)
OCULAR INFECTIONS IN HORSES
Streptococcus equi ssp. zooepidemicus
Streptococcus equisimilis
Actinobacillus equuli
Pseudomonas aeruginosa- (GM- bacilli; aerobic; corneal ulcers that are slow to heal
(All found in env. of horses and usually cause Dz after trauma)

Aspergillus fumigatus- KERATOMYCOSIS (infection usually follows prolonged tx w/ topical ABs or steroids; cornea becomes opaque and vascularized)
MOST COMMON CAUSE OF BLINDNESS IN HORSE
Leptospira interrogans serovar pomona! RECURRENT UVEITIS (bacteria spread systemically to eye; recurrent episodes of inflammation of one or both eyes occurs)
OCULAR INFECTIONS IN DOGS
1. COAGULASE + STAPHYLOCCI
2. alpha or beta hemolytic STREPTOCOCCI
3. STAPHYLOCOCCUS EPIDERMIDIS
4. ESCHERICHIA COLI
5. PROTEUS MIRABILIS
(They cause corneal ulcers with creamy white infiltrate; purulent ocular discharge)

6. Aspergillus- KERATOMYCOSIS (occurs with some predisposoing cond. such as, glucocorticoid therapy, diabetes, or long term AB therapy)
OCULAR INFECTIONS IN CATS
Chlamydophila felis- (starts unilaterally--> bilaterally w/in a few days; ocular discharge & blepharospasm; POTENTIAL ZOONOSIS)
Mycoplasma felis
Mycoplasma gatae
(These 2 result in serous to mucoid conjunctivitis w/ edematous conjunctiva (no corneal involvement)
Histophilus somni
CATTLE- (6-12mos)THROMBOTIC MENINGOENCEPHALITIS (neuro signs are preceeded for 1-2 wks by DYSPNEA and a DRY HARSH COUGH; fever, depression, eyes partially or fully closed, ataxia, weakness, knuckling over, RAPIDLY FATAL in 8-12 hrs.)

GM-bacilli; fac. anaerobe

Mucosal sites in Dz'ed and subclin. animals; most common colonizing resp tract.
Listeria monocytogenes
CATTLE, SHEEP & GOATS- ENCEPHALITIS, CIRCLING Dz, SILAGE Dz (anorexia, depression, fever in early stage then disappears, animals circle in one direction, head tilts to one side or ear droops, unilateral facial paralysis--> animal will become recumbent and unable to rise)

GM+ bacilli; fac. anaerobe

SOIL, SEWAGE, WATER, SILAGE, and Alimentary tract of variety of animals

ZOONOTIC
Streptococcus suis
PIGS (few weeks post-weaning)- MENINGITIS (development assoc. w/ stresses of moving, mixing of pigs, overcrowding, and poor ventilations) (1st sign inc. rectal temp--> anorexia and depression, then signs of MENINGITIS incl. incoordination & unusual stances such as on toes--> inability to stand, paddling, opisthotonus, and convulsions, ears often retracted to head; also causes septicemia, arthritis and pneumonia)

GM+ cocci (pairs or chains); non-spore forming; anaerobic

COMMENSAL of URT, esp tonsils, of healthy pigs

ZOONOTIC (rare but FATAL)

EPIDEMICS--> 1st signs may be sudden death
Clostridium tentani
ALL SPECIES but cat and avian spp.- SPASTIC PARALYSIS (Horses and humans most susceptible) (gen. increase in muscle stiffness, muscle tremor, trismus (motor distubance of trigeminal nerve) w/ restriction of jaw movements, prolapse of 3rd eyelid, stiffness in hind limbs causing unsteady, straddling gait and the tail is held out stiff)

(Early stages- animals continue to eat and drink but mastication is soon prevented by tetany of masseter muscles; saliva may drool from mouth)

As Dz progresses, muscular tetany increases; animal adopts SAWHORSE posture; walking becomes difficult and animals tend to fall; once down can't really get up; DEATH due to RESP ARREST.

GM+ bacilli; obligate anaerobe; spore-forming, which are terminally located

SOIL contaminated with FECES; often transient in INTESTINES of animals; WW; entry thru penetrating wounds

HUMANS GET IT TOO!!! (not really zoonotic though)
Clostridium botulinum
CATTLE, HORSES, SHEEP&GOATS, BIRDS/TURKEYS/CHICKENS
FLACCID PARALYSIS
(Muscle weakness starts in hindquarters and progressed to the forequarters, head and neck; restlessness, incoordination, stumbling, knuckling, ataxia, and inability to rise or lift head; animals are found with head on the ground or turned into the flank; sensation & consciousness are retained until death; paralysis of chest muscle result in terminal abd. type respiration)
SHEEP- (don't show flaccid paralysis until final stages of disease; early signs- stiffness while walking, and incoordination; head may be heald to one side or bobbed up and down while walking. Terminal stages- abd. resp and limb paralysis are seen--> RAPID DEATH)

BIRDS- (flaccid paralysis of legs, wings, neck and eyelids progress cranially from the legs; initially birds are sitting and relunctant to move; appear lame and wings droop LIMBERNECK-comes from appearance of paralyzed neck--> DEATH due to RESP. and CARDIAC failure)

FOALS (3-8wks old)- SHAKER FOAL SYNDROME (sudden onset of severe muscular weakness and prostration; foal goes down and is unable to rise; animal appears bright and alert; gross muscle tremor is obvious if foal is held up; animal goes through periods of rising then onset of tremor, recumbency, and complete prostration; when animal can walk the walk is stiff and stilted and the toes are dragged; later peristalsis is halted and pupils dilate--DEATH ~72 hrs after onset of signs due to resp failure.

GM+ bacilli; spore-forming, which are subterminally located; obligate anaerobe

GROWS on decomposing animal or plant material; COMMENSAL of ALIMENTARY TRACT OF HERBIVORES; DISEASE IS an INTOXICATION rather than an infection
Crytococcus neoformans
DOGS & CATS & HUMANS
Infections localizes to CNS following dissemination from lungs
(Depression, changes in temperament, seizures, circling, head pressing, ataxia, loss of smell, and blindness; ulcerative lesions in MM in nose, mouth and pharynx also common-hematogenous spread)

YEAST-forms single buds attached by slender stalks; sexually reproducing phase is a basidiomycete

BIRD, esp pigeons, carry fungus in their INTESTINAL TRACT; not contagious
Name the bacteria that causes ascending UTIs in Cattle.
Corynebacterium renale
Name the 2 bacteria that can cause infertility in Cattle.
Campylobacter fetus ssp. veneralis

Mycoplasma bovigenitalium
Name the 5 bacteria that can cause ABORTIONs in Cattle.
Leptospira serovars pomona, hardjo

Campylobacter fetus ssp. veneralis

Brucella abortus

Ureaplasma diversum

Listeria monocytogenes
Name the 4 bacteria that can cause vulvovaginitis/endometritis in Cattle.
Campylobacter fetus ssp. veneralis

Mycoplasma bovigenitalium

Ureaplasma diversum

Listeria monocytogenes
Name the bacteria that can cause ABORTIONS in horses.
Leptospira serovars pomona, grippotyphosa, icterohaemmorrhagiae
Name the bacteria that causes acute ENDOMETRITIS in horses.
Taylorella equigenitalis
Name the bacteria that can cause ascending UTIs in pigs.
Actinobaculum suis
Name the 2 bacteria that can cause ABORTIONS in pigs.
Leptospira serovars icterohaemorrhagiae, canicola, grippotyphosa

Brucella suis
Name the bacteria that can cause UTI's and PIZZLE ROT in male sheep and goats.
Corynebacterium renale
Name the 4 bacteria that can cause abortions in sheep.
Campylobacter fetus ssp. fetus

Brucella melitensis, ovis

Chlamydophila abortus

Listeria ivanovii
Name the 3 bacteria that can cause abortions in goats
Brucella melitensis

Chlamydophila abortus

Listeria ivanovii
Name the bacteria that causes abortion storms in sheep and goats.
Brucella melitensis
Name the 6 bacteria that can cause UTIs (ascending) in dogs.
Escherichia coli (Necrotoxigenic)

Enterococcus spp.

Coagulase + staphylococci

Proteus mirabilis

Klebsiella spp.

Pseudomonas aeruginosa
Name the 2 bacteria that can cause abortions in dogs.
Leptospira serovars canicola, icterohaemorrhagiae, pomona, grippotyphosa

Brucella melitensis biovar canis
Name the bacteria that can cause renal involvement, hepatic dz, as well as other systemic dz's and abortions in dogs.
Leptosira serovars canicola, icterohaemorrhagiae, pomona, grippotyphosa
Name the 4 urogenital bacteria that are ZOONOTIC.
Leptospira serovars

Brucella spp.- UNDULANT FEVER

Chlamydophila abortus

Listera monocytogenes
Classify Escherichia coli, Proteus mirabilis, and Klebsiella spp. in regards to urogential tract infections.
FAMILY ENTEROBACTERIACEAE

GM- bacilli, fac. anaerobe

DOGS- UTI that can lead to ascending infections-->bladder (cystitis), inducing inflammation leading to dysuria, pollakuria, and urgency, hematuria, and incontinence. Can get infection spread to kidneys (pyelonephritis); fever, pain over the kidneys, depression, and anorexia.

Type I pili/ P (pap) pili (UPEC).

Proteus Mirabilis produces urease (making urine alkaline, leading to production of uroliths)

Organisms are found in intestines and soil, water and on plants
Classify Enterococcus in regards to urogenital tract infections.
GM+ cocci in pairs or chains.

DOGS- UTI that can lead to ascending infections-->bladder (cystitis), inducing inflammation leading to dysuria, pollakuria, and urgency, hematuria, and incontinence. Can get infection spread to kidneys (pyelonephritis); fever, pain over the kidneys, depression, and anorexia.

Commensal of alimentary tract of animals.
Classify Coagulase + Staphylococci spp. in regards to urogential tract infections.
GM+ cocci in clusters, pairs or short chains.

DOGS- UTI that can lead to ascending infections-->bladder (cystitis), inducing inflammation leading to dysuria, pollakuria, and urgency, hematuria, and incontinence. Can get infection spread to kidneys (pyelonephritis); fever, pain over the kidneys, depression, and anorexia.

Commensals of distal nasal passages, external nares, skin (esp. near perineum, external genitalia, and bovie udder)
Classify Pseudomonas aeruginosa in regards to urogenital tract infections.
GM- bacillus

DOGS- UTI that can lead to ascending infections-->bladder (cystitis), inducing inflammation leading to dysuria, pollakuria, and urgency, hematuria, and incontinence. Can get infection spread to kidneys (pyelonephritis); fever, pain over the kidneys, depression, and anorexia.

Soil and Water
Characterize Corynebacterium renale.
GM+ diphtheroid, fac. anaerobe

CATTLE- UTIs-> ascending infections--> cystitis, ureteritis, and then pyelonephritis; most common in cows near parturition; pollakuria, hematuria, and increasing abdominal pain; chronic cases can lead to debilitation and death due to uremia.

SHEEP & GOATS- MALES- posthitis (PIZZLE ROT!); necrotizing inflammation of the prepuce and adjacent tissues--> occurs mostly with animal on rich legume pastures high in proteins

VIRULENCE- Adherent bacteria produce urease--> ammonia makes urine alkaline, suppressing complement, enhancing survival of bacteria in bladder; also induces tissue damage, resulting in inflamm. response that furthers damage.

Commensal of lower genital tract of ruminants (infections usually endogenous; bacterium trans venerally by contaminated urine)
Characterize Actinobaculum suis.
GM+ diphtheroid, obligate anaerobe.

PIGS- UTI's-> ascending infections; mostly cystitis but also ureteritis and pyelonephritis. (URINE contains CLOTS of BLOod and PURULENT material)

VIRULENCE- fibrillar surface structures for attachment to uroepithelium; adherent bacteria produce urease--> ammonia makes urine alkaline, suppressing complement, enhancing survival of bacteria in the bladder.

COMMENSAL of prepuce in male pigs, rarely isolated from FEMALE PIGS; transmission is VENEREAL. (Dz often related to breeding, pregnancy, and partuition.)
Characterize Leptospira spp. in regards to Urogenital tract infections.
GM- Spirochetes (tightly coiled w/ hooked ends); obligate aerobes

DOGS- initial signs-->depression, anorexia, vomiting, and diarrhea; acute dz--> fever, shivering, and muscle tenderness--> vomiting, dehydration, tachypnea, coag. defects (FATAL); subacute dz--> FAD, vomting, dehydration and increased thirst, coughing, dyspnea, and signs of renal deterioration (oliguria or anuria)

CATTLE- fever, diarrhea, anemia, icterus, and hemoglobinuria (fatal 5-15%) ABORTION, reproductive failure and infertility, MILK DROP SYNDROME.

PIGS- Unthriftiness, ABORTION, fever, icterus, anemia

EQUINE- Icterus and depression--> ABORTION and periodic ophthalmia (recurrent attacks lead to blindness)

VIRULENCE- bacteria down-regulate outer membrane protein synthesis, which aids in persistance in the host; also produce a membrane damaging toxin; most damage due to induction of inflamm. response

Bacteria are maintained in the tubules of mammalian kidneys.

ZOONOTIC
Characterize Campylobacter fetus ssp. fetus.
GM- curved bacillus; microaerophilic

SHEEP- aborions; placentitis

VIRULENCE- S-layer protein that forms paracrystalline arrays on the surface of bacteria; inhibiting the deposition of complement.

COMMENSAL of intestines of healthy sheep and cattle; trans by ingestion of material contaminated with organism
Characterize Campylobacter fetus ssp. venerealis
GM- curved bacillus; microaerophilic.

CATTLE- infertility and ABORTION


VIRULENCE- S-layer protein that forms paracrystalline arrays on the surface of bacteria; inhibiting the deposition of complement.

Found in preputial crypts of bulls and the vagina of carrier animals.
Characterize the bacteria Brucella abortus.
GM- coccobacilli; strict aerobes

CATTLE- BANGS Dz; ABORTION (5th month); lameness and mastitis may also be present; MALES- epididymitis and orchitis

VIRULENCE- fac. intracellular parasites of macrophages; prevent phagolysosome fusion and multiply in the phagosome; produce superoxide dismutase and catalase, which help them avoid being killed by respiratory burst.

Found in infected animals; trans by ingestion, penetration of skin, and inhalation

ZOONOTIC
Characterize the bacteria Brucella melitensis.
GM- coccobacilli; strict aerobes

GOATS AND SHEEP- ABORTION; Mastitis in goats; ABORTION STORMS; MALES- orchitis

VIRULENCE- fac. intracellular parasites of macrophages; prevent phagolysosome fusion and multiply in the phagosome; produce superoxide dismutase and catalase, which help them avoid being killed by respiratory burst.

Found in infected animals; trans by ingestion, penetration of skin, and inhalation

ZOONOTIC
Characterize the bacteria Brucella ovis.
GM-coccobacilli; strict anaerobes

SHEEP- late ABORTIONS and STILLBIRTHS; Infertility in MALES due to epididymitis--> Fever, depression, and inc. resp. rates, acute edema and inflammation of the scrotum


VIRULENCE- fac. intracellular parasites of macrophages; prevent phagolysosome fusion and multiply in the phagosome; produce superoxide dismutase and catalase, which help them avoid being killed by respiratory burst.

Found in infected animals; trans by ingestion, penetration of skin, and inhalation

ZOONOTIC
Characterize the bacteria Brucella suis.
GM- coccobacilli; strict aerobes

SWINE- Sterility and ABORTIONS; heavy piglet mortality; MALES- orchitis; extragenital manifestations include lymphadenitis, arthritis in the large joints of the limbs, and lumbar spondylitis


VIRULENCE- fac. intracellular parasites of macrophages; prevent phagolysosome fusion and multiply in the phagosome; produce superoxide dismutase and catalase, which help them avoid being killed by respiratory burst.

Found in infected animals; trans by ingestion, penetration of skin, and inhalation

ZOONOTIC
Characterize the bacteria Brucella canis.
GM- coccobacilli; stict aerobes

DOGS- ABORTIONS (45-60days); conception failures common; MALES- enlarged scrotum due to enlargement of the tail of the epididymis; not commonly--> meningoencephalitis, osteomyelitis, discospondylitis, and anterior uveitis.


VIRULENCE- fac. intracellular parasites of macrophages; prevent phagolysosome fusion and multiply in the phagosome; produce superoxide dismutase and catalase, which help them avoid being killed by respiratory burst.

Found in infected animals; trans by ingestion, penetration of skin, and inhalation

ZOONOTIC
Characterize the bacteria Taylorella equigenitalis.
GM-coccobacillus; fac. anaerobe

EQUINE- contagious equine METRITIS- approx. 8-10 days after breeding to an infected stallion, acute endometritis occurs--> odorless mucopurlent uterine discharge--> may lead to INFERTILITY

VIRULENCE- CAPSULE

Found in clitoral sinuses of carrier males and in the prepuce and urethra of stallions; trans venereally.
Characterize the bacteria Chlamydophila abortus.
GM- (can't see with a GM stain); obligate intracellular parasites

SHEEP & GOATS- ABORTION (4th or 5th month of gestation)

VIRULENCE- outer membrane proteins in the elem. bodies are involved in bacterial adherence and invasion of cells and inhibition of phagosome-lysosome fusion; damage due to cell lysis and the inflamm. response that is induce

Found in the respiratory, intestinal, and genital tracts of mammals and birds; infection is by ingestion of infectious material

ZOONOTIC
Characterize the bacteria Listeria monocytogenes in regards to Urogenital tract infections.
GM+ bacilli; fac. anaerobes

CATTLE- ABORTIONS in last 2 months of gestation

VIRULENCE- produce an invasion protein called internalin, which binds E-cadherin on intestinal epithelium and induces uptake of bacteria--> phagocytic cells where they escape from the phagocytic vacuole due to production of the membrane damaging toxins listeriolysin O

Found in SOIL, SILAGE, SEWAGE, WATER and Alimentary tract of a variety of animals; infection via ORAL route (often w/ feeding of silage w/ elevated pH)

ZOONOTIC
Characterize the bacteria Listeria ivanoii in regards to Urogenital tract infections.
GM+ bacilli; fac. anaerobes

SHEEP & GOATS- ABORTIONS

VIRULENCE- produce an invasion protein called internalin, which binds E-cadherin on intestinal epithelium and induces uptake of bacteria--> phagocytic cells where they escape from the phagocytic vacuole due to production of the membrane damaging toxins listeriolysin O

Found in SOIL, SILAGE, SEWAGE, WATER and Alimentary tract of a variety of animals;

ZOONOTIC
Characterize the bacteria Mycoplasma bovigenitalium.
NO CELL WALL; contains cholesterol from host; small pleiomorphic cells; fac. anaerobes.

CATTLE- granular vulvovaginitis and less commonly endometritis; often get INFERTILITY

COMMENSAL of MM of genital tract; trans venereally.
Characterize the bacteria Ureaplasma diversum.
NO CELL WALL; cholesterol derived from host; small pleomorphic cells; fac. anaerobes

CATTLE- granular vulvitis--> reddish nodules on the vulvar mucosa accomp by mucopurulent discharge; Uterine involvment is rate--> if present may cause conception failure, early embryonic death or abortion.

Found in prepuce and semen of clinically normal males; Trans venereally