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28 Cards in this Set

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nephron consists of two embryologically different parts:
Renal corpuscle

collecting tubule

derived from =
intermediate mesoderm

metanephric diverticulum.
***
The kidneys are first located in the ________ ventral to the ______ but gradually _______ =
pelvis

sacrum

ascend to the abdomen

They reach the adult position by week =
wk 9
The kidneys rotate 90 degrees from _____ to _____ =
anterior to medial.
Dz Clinical Considerations
5ct
Accessory Renal arteries
Renal agenesis
Ectopic kidneys
Horseshoe kidney
Cystic kidney disease
. Accessory Renal arteries : associated with Hydronephrosis =
dictate
Renal vein
renal artery
interlobar vessels
interlobar arteries
interlobar veins
arcuate vessels

Accessory renal arteries associated with hydronephrosis
2. Renal agenesis :
occurs when the
ureteric bud fails to develop, thereby eliminating the induction of metanephric vesicles and nephron formation.
2 types of renal agenisis
Unilateral renal agenesis
Bilateral renal agenesis
1 Unilateral renal agenesis :
is relatively common (more common in males). This situation is asymptomatic and compatible with life because the remaining kidney hypertrophies.
2. Bilateral renal agenesis
▪is relatively uncommon
▪It causes oligohydramnios, causing compression of fetus, aka =

▪Infants with bilateral renal agenesis are usually stillborn or die shortly after birth.
Potter syndrome
(deformed limbs, wrinkly skin, and abnormal facial appearance).
occurs when there is a congenitally small kidney with no pathologic evidence of dysplasia =
Renal hypoplasia :
there is a disorganization of renal parenchyma with abnormally developed and immature nephrons. =
Renal dysplasia :
Renal dysplasia :
occurs when there is a =
there is a disorganization of renal parenchyma with abnormally developed and immature nephrons.
occurs when one or both kidneys fail to ascend and therefore remain in the pelvis or lower lumbar area (i.e., pelvic kidney).
Renal ectopia :

In some cases, two pelvic kidneys fuse to form a solid mass, commonly called a =
pancake kidney.
Ectopic kidneys take their blood supply from =
the vessels closest to them at the end of their limited ascent.
The most common type of renal fusion
horseshoe kidney.
A horseshoe kidney occurs when
the inferior poles of the kidneys fuse across the midline.
Normal ascent of the kidneys is arrested because the fused portion gets trapped behind the =
inferior mesenteric artery.
Kidney rotation is also arrested so that the hilum faces
ventrally
►Horseshoe kidney is found in =

►The prevalence of horseshoe kidneys in females with Turner Syndrome is about =
1/600 people (1 in 400 people).

15%.

►It can be associated with trisomy ___ =
18
Renal fusion :
The most common type of renal fusion is =
horseshoe kidney
is the most common cause of renovascular hypertension in children.=
Renal artery stenosis :
The stenosis may occur in the main renal artery (of segmental renal arteries).
The stenosis may occur in the main renal artery (of segmental renal arteries).
Renal artery stenosis :
is the most common cause of renovascular hypertension in children.=
Renal artery stenosis :
THIS Dz CAN PRESENT FROM EITHER

autosomal recessive
or
autosomal dominant disorder
Congenital polycystic kidney:
characterized by the presence of multiple cysts in both kidneys
PCKD

It may be inherited as an =
autosomal recessive
or
autosomal dominant disorder
PCKD
2 types:
Childhood
autosomal recessive disease

Adult
Autosomal Dominent disease
Chromosome # __ ?
16
PCKD
Autosomal Dominent (kind) =
autosomal recessive disease (kind) =
Adult Chromosome number ? =

Childhood
16
16
Renal blood vessels:
-Renal artery
-segmental artery
-interlobar artery
-arcuate artery
-interlobular artery
-afferent arterial
-glomerulus
-efferent
peritubular capillaries
(cortical nephron)
-vasa recta
(juxtamedullary nephron)

Nm Veins =
peritubular capillaries (cortical nephron)
vasa recta (juxtamedullary nephron)
interlobular vein
arcuate vein
interlobar vein
Renal vein
-interlobular vein
-arcuate vein
-interlobar vein
-Renal vein