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41 Cards in this Set

  • Front
  • Back
________ means that information flows from genes to proteins.
Gene expression
In gene expression, information flows from _____ to _____.
genes, proteins
Gene expression is mainly controlled by controlling _______?
transcription
Differentiation involves cell specialization in both _____ and _____.
structure, function
Differentiation is controlled by turning specific sets of genes ___ or ___.
on, off
Each cell in a human body has ____ chromosomes?
46
DNA wrapped around histone proteins
nucleosomes
In nucleosomes, each bead includes ___ plus 8 ____ molecules?
DNA, histone
DNA packing can prevent ______?
transcription
a coiling of the tight helical fiber
supercoil
In female mammals, one X chromosome is _____ in each somatic cell.
inactive
An inactivated X chromosome is called _____?
a Barr Body
Athletes may be tested for _____ to determine sex?
Bar bodies
In female mammals, one of the two X chromosomes is coiled tightly and not ______.
transcribed
In eukaryotic transcription, each gene has a _____ and a ______.
promoter, terminator
Interactions between ______ proteins and control sequences maintain control of activation/expression?
regulatory proteins
______, a type of regulatory protein, inhibit transcription?
Silencers
replacing the nucleus of an egg cell or zygote with a nucleus from an adult somatic cell
nuclear transportation
implant embryo in surrogate mother for development; new animal is genetically identical to nuclear donor
reproductive cloning
remove embryonic stem cells and grow in culture for medical treatments; induce stem cells to differentiate
therapeutic cloning
early embryo
blastocyst
Cloned animals can show differences from their parent due to a _____ of influences during development.
variety
Reproductive cloning is used to produce animals with _____ traits.
desirable- agricultural products, therapeutic agents, restoring endangered animals
In therapeutic cloning, stem cells can be induced to give rise to _____?
differentiated cells
Cancer results from _____ in genes that control cell division.
Mutations
Mutations in two types of genes can cause cancer:
oncogenes, tumor-suppressor genes
Proto-oncogenes normally ____?
promote cell division
Mutations to oncogenes _____ activity.
enhance
Tumor suppressor genes normally ______?
inhibit cell division
Mutations to tumor suppressor genes inactivate the genes and allow ______ division to occur.
uncontrolled
What type of genes promote cancer when present in a single copy?
oncogenes
Oncogenes can be ____ genes inserted into host chromosomes.
viral
Oncogenes can be mutated version of _____, which are normal genes that promote cell division and differentiation.
proto-oncogenes
Converting a proto-oncogene to an oncogene can occur by a mutation increasing ____ activity, an increased number of _____ copies causing more protein to be produced, or a change in location that puts the gene under the control of a new promoter for increased _____.
protein, gene, transcription
When both copies of ______ genes are mutated, they promote cancer.
tumor-suppressor
____ or more somatic mutations are usually required to produce a cancer cell.
4
cancer causing agents that damage DNA and promote cell division
carcinogens
types of cancer caused by cigarettes
lung, colon/rectum, urinary bladder, kidney, pancreas, mouth and throat, stomach, cervix
a group of genes under coordinated control in bacteria
operon
two types of operon control
1. inducible operon
2. repressible operon
For many operons, ______ enhance RNA polymerase binding to the promoter.
activators