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29 Cards in this Set

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Alpha glucose

Hexose sugar

Beta glucose

Hexose sugar

Ribose

Pentose sugar

Saturated fatty acid

Amino acid- labelled

Nucleotide

Triglyceride

Phospholipid

Steroid

Dipeptide formation

DNA chain

General monosaccharide

Anabolism

Build up polymers from monomers via condensation reaction.

Anna the builder

Catabolism

Break polymers into monomers via hydrolysis reaction

Break-dancing cat

Lactose

Enzyme-substrate complex

Substrate binds to enzyme's active site

Enzyme-product complex

Enzyme catalyses conversion of substrate into product

Benefits of lactose-free milk

- increases sweetness of milk


- reduces crystallization of ice cream


- cheese/yoghurt made faster


- lactose intolerant people can still drink it

Alginate beads

Inert substance used to make lactose free milk. Lactase bound to them.

Metabolic chain example

Glycolysis- cell respiration


Coagulation cascade- blood clotting

Metabolic cycle example

Krebs cycle- cell respiration


Calvin cycle- photosynthesis

Competitive inhibition

A molecule similar to the substrate binds to the active site which prevents the substrate from binding. It's effect can be reduced by increasing the substrate concentration.

Non competitive inhibition

A molecule binds to the allosteric site causing a structural change to enzyme's active site so the substrate is no longer complementary.

Competitive inhibitor example

Relenza- drug to treat influenza.


Enzyme neuramindase cleaves a docking protein to prevent virioles from being released.

Non competitive inhibitor example

Cyanide- prevents ATP production via aerobic respiration. Binds to allosteric site of cytochrome oxidase so it can't pass electrons to oxygen.

End- product inhibition

Negative feedback.


Final product inhibits an enzyme from earlier in the reaction. Product binds to allosteric site to temporarily inactivate the enzyme so reaction sequence is halted. Ensures production is regulated.

End- product inhibition example

Isoleucine- essential amino acids. Foods rich in it include cheese, fish and eggs. In plants and bacteria it may be synthesized from threonine deaminase and isoleucine binds to its allosteric site.

Effect of inhibitors

Malaria

Parasitic protozoans of plasmodium- requires a human and mosquito host. Enzymes involved in parasites metabolism can be targeted as their proteom has been mapped.