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69 Cards in this Set

  • Front
  • Back

Disinfection

A process to destroy vegetative pathogens, not endospores, on inanimate objects.

Sterilization

A process that destroys all viable microbes, including viruses and endospores. (Kills all bacteria and endospores).

Antisepsis

Disinfection of exposed body surfaces (living) .(on the baby)

Sanitization

Any cleansing technique that mechanically removes microbes.

Thermal Death Time

Shortest length of time required to kill all test microbes at a specified temperature.

Thermal Death Point

Lowest temperature required to kill all microbes in a sample in 10 minutes.

Tyndallization

Intermittent sterilization for substances that cannot withstand autoclaving.

Pasteurization

Application of heat to kill potential agents of infection and spoilage without destroying the food flavor or value.

Pasteurization in.






Batch Method

Pasteurization at 65 C for 30 minutes. (LTLT).

Pasteurization in.




Flash Method

Pasteurization at 70 C. For 15 seconds (HTST)

Lyophilization

Freeze drying; preservation.

Antibiotics

Are common metabolic products of aerobic spore-forming bacteria and fungi, that can destroy infectious agents. Example: penicillin.

Antimicrobials

Any drug that can destroy an infective agent.

Bacteriocidad

Any drug administered to a person that kills bacteria.

Bacteriostatic

Any drug administered to a person that suppresses (holds it) bacterial growth.

Therapeutics

Any drugs used to cure ar alleviate signs and symptoms of a disease.

Prophylaxis

Any drug of immunization that prevents a person from getting a specific disease.

Broad Spectrum

Antibiotics that target cell component common to most pathogens and therefore have a greatest range of activity against microbes.

Narrow Spectrum

Antibiotics that target a specific cell component found only in certain microbes and are therefore effective only on a small range of microbes.

Antibiogram

A list of antibiotics with their effectiveness agains a bacterial culture.

Therapeutic Index

A ratio of the toxic dose of a drug to its minimum effective dose.

Therapeutic index =

Toxic dose


_______________________________________________




Minimum effective dose




Higher the therapeutic index of a drug, better the safety margin and effectiveness.

Infection

A condition in which pathogenic microbes penetrate host defenses, enter tissues and multiply.

Disease

Any deviation from health, disruption of a tissue or organ

Infectious disease

Any deviation from health, disruption of a tissue or organ caused by an infectious agent.

Normal flora

Microbes that engage in mutual or commensal associations with the host (resident flora indigenous flora)

True pathogen

Capable of causing disease in healthy persons with normal immune defenses.

Opportunistic pathogen

Causes disease when the host's defenses are compromised or when they grow in part of the boby that is not natural to them.

Virulence

Ability of a microbe to cause disease.

Virulence factors

Characteristic or structure of a pathogen that contributes to virulence.

Exogenous agent

Microbes that originate from sources outside the body to cause infection.

Endogenous agent

Microbes that already exist on or in the host body (normal flora) to cause infection.

Infectious dose

Minimum number of microbes required to cause an infection.

Endotoxins

Lipopolysachcharides found on outer membranes of Gram-negative bacteria. (Part of the organism inside).

Exotoxins

Protein secreted by Gram-positive and Gram-negative bacteria.

Stages of infection

Incubation period, prodromal stage, period of invasion, convalescent period. (Exposed to a agent).

Localized infection

Microbes enter body and remain confined to a specific tissue.

Systemic infection

Infection spreads to several sites and tissue fluids usually through the bloodstream.

Focal infection

When infectious agent breaks loose from a local infection and is carried to other tissues.

Primary infection

Initial infection by a microbe.

Secondary infection

Another infection by a different microbe subsequent to primary infection.

Mixed infection

Several microbes growing simultaneously at the infection site.

Acute infection

Infection comes on rapidly, with severe but short-lived effects.

Chronic infection

Infection progresses and persist over a long period of time.

Signs of disease

Objective evidence (can be measured or visualized) of disease as noted by an observer.

Symptoms of disease

Subjective evidence of disease as sensed by the patient.

Bacteremia

Bacteria in small numbers in blood and may not cause systemic disease.

Viremia

Virus in small numbers in blood and may not cause systemic disease.

Septicemia

Bacteria in large number in blood circulation and can cause disease in any organ.

Portals of entry

Part of body of a host through which a microbe gains entry to cause infection.

Portals of exit

Part of body of an infected host through which a microbe exists.

Reservoir of pathogen

Primary habitat of pathogen in the natural world.

Source of infection

Individual or object from which an infection is actually acquired.

Asymptomatic carriers

An individual who inconspicuously shelters a pathogen and spreads it to others.

Passive carriers

A healthcare provider who picks up pathogens from a patient and transfers them to other patients is considered a passive carrier.

Vector

Any animal (usually arthropods) that transmit microbes from one host to another.

Biological vector

Vector which actively participates in a pathogen's life cycle.

Mechanical vector

Vector that is not necessary to the life cycle of an infectious agent and merely transport it without being infected.

Communicable disease

When an infected host can transmit the infectious agent to another host and establish infection in that host.

Contagious disease

Highly communicable disease.

Notifiable disease

A communicable disease that, when diagnosed or suspected by a clinician, must be notified to the health authorities.

Prevalence

Total number of existing cases with respect to the entire population usually represented by a percentage of the population.

Incidence

Measures the number of new cases over a certain time period, as compared with the general healthy population.

Mortality rate

The total number of deaths in a population due to a certain disease.

Morbidity rate

Number of people afflicted with a certain disease. Example: Ebolla.

Endemic

Disease that exhibits a relatively steady frequency over a long period of time in a particular geographic locale.

Epidemic

When prevalence of a disease is increasing beyond what is expected.

Pandemic

Disease epidemic across continents.

Sporadic outbreak

When occasional cases of a disease are reported at irregular intervals.