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78 Cards in this Set

  • Front
  • Back

How are exocrine glands classified?

By mode of secretion


number of cells


Morphology of gland

Modes of Secretion: Merocrine

Product released by exocytosis

Modes of Secretion: Aprocrine

Apical portion of cytoplasm of cell becomes packed with secretory vesicles containing product and is then shed

Modes of Secretion: Holocrine

The entire cell becomes packed with secretions and bursts apart

Unicellular glands/Multicellular glands

composed of only one cell


composed of more than one cell

Goblet cells

Unicellular exocrine glands that produce mucus that protects and lubricates many internal body surfaces

What are the 2 basic parts that make up multicellular glands?

1. Epithelium-walled duct: conducts secretion to the surface of the epithelium


2. Secretory Unit: cells are specialized for secretion

What are the most diverse and abundant tissues in the human body?

Connective tissues

What do all connective tissue derive from?

A common embryonic origin, embryonic tissue called mesenchyme

General connective tissue characteristics

- cells are specialized and separated by large amounts of extracellular matrix


- often underlies epithelial tissues


- highly vascularized (lots of blood supply) and richly innervated (supplied with nerves)

What is extracellular matrix composed of?

A ground substance and protein fibers

Connective Tissue Functions

- structural framework of the body


- fluid and solute transport throughout the body


- physical protection


- tissue interconnection and binding


- fat storage


- microorganism defense

Connective Tissue (c.t.) equation

c.t. = cells + extracellular matrix

Extracellular matrix composition (ECM) equation

ECM = protein fibers + ground substance

Connective Tissues are made up of what?

cells, fibers, and ground substance

Fibroblast

cells that produce the protein portion of the extracellular matrix and secrete molecules that form the ground substance

Chondroblast

In cartilage, specialized cells secrete the extracellular matrix (while in bone called osteoblasts) FIBROBLASTS

Fibrocytes

Cells that are no longer secreting matrix; instead they maintain and repair existing extracellular matrix

Chondrocytes

In cartilage, specialized maintenance cells (while in bone called osteocytes) FIBROCYTES

Macrophages

cells that phagocytize (engulf and destroy) pathogens, cell debris, and other foreign material

Adipocytes (fat cells)

Resident cells that fill with liquid fat to store nutrients and have nuclei flattened and pushed to one side of the fat droplet

Mast cells

promote inflammation in response to infection or allergic reactions

What is the extracellular matrix produced by and composed of?

1. fibroblasts


2. ground substance and protein fibers

Ground Substance

Hydrophilic substance in which the cells and protein fibers are embedded. Usually syrupy consistency, but ground substance can vary in consistency

Protein fibers

Provide support in the extracellular matrix

3 types of protein fibers in extracellular matrix

Collagen fibers, reticular fibers, elastic fibers

Collagen fibers

Strongest and most abundant fibers that resist tension and provide flexibility to tissues

Reticular fibers

Mesh-like network of protein fibers that provide tissue flexibility and support structures within

Elastic Fibers

Contain elastin that has the ability to stretch and then recoil

4 broad classes of connective tissues

1. Connective tissue proper: syrupy consistency to the ground substance


2. Cartilage: gelatinous consistency to the ground substance


3. Bone: crystalized consistency to the ground substance


4. Blood: liquid consistency to the ground substance

What is connective tissue proper characterized by?

A syrupy ground substance and the presence of fibroblasts, fibrocytes, defense cells, and adipocytes

Loose connective tissues

Protein fibers are present but they are separated from one another by ground substance


- areolar connective tissue


- adipose connective tissue


- reticular connective tissue

Dense connective tissues

Protein fibers are densely packed with little ground substance between them


- dense irregular connective tissue


- dense regular connective tissue


- elastic connective tissue

Areolar Connective Tissue Functions

- wraps and cushions organs


- holds and conveys tissue fluid


- important role in inflammation


- main defense site against infection


(highly regenerative!)

Areolar Connective Tissue Locations

- widely distributed under epithelia


- packages organs

Adipose Connective Tissue Functions

- provides reserve food fuel


- insulates against heat loss


- supports and protects organs

Adipose Connective Tissue Locations

- under skin


- around kidneys


- within abdomen and in breasts

Reticular Connective Tissue Functions

Forms a soft, internal skeleton for lymphoid organs that supports other cell types

Reticular Connective Tissue Locations

- lymph nodes


- spleen

Dense Irregular Connective Tissue Functions

- withstands tension from many directions


- provides structural strength


(highly regenerative!)

Dense Irregular Connective Tissue Locations

- dermis of skin


- fibrous capsules of joints and organs

Dense Regular Connective Tissue Functions

- attaches muscle to bone (tendons) and bone to bone (ligaments)


- withstands great stress in one direction

Dense Regular Connective Tissue Locations

- tendons


- ligaments

Elastic Connective Tissue Functions

Allows recoil after stretching

Elastic Connective Tissue Locations

- within walls of arteries


- surrounding bronchial tubes

What is cartilage characterized by?

A firm, flexible gel matrix containing mostly water and protein fibers

What are the specialized cells found in cartilage?

Chondroblasts (immature cells that lay down new extracellular matrix in cartilage) and Chondrocytes (mature cells that maintain the extracellular matrix in cartilage)

What are cartilages?

Avascular and non-innervated so it is only weakly regenerative

3 types of cartilage

1. hyaline cartilage


2. elastic cartilage


3. fibrocartilage

Hyaline Cartilage Functions

- supports and reinforces


- resists repetitive stress

Hyaline Cartilage Locations

- fetal skeleton


- ends of long bones


- costal cartilage of ribs

Elastic Cartilage Functions

- maintains shape of structure


- allows great flexbility

Elastic Cartilage Locations

- supports external ear


- epiglottis

Fibrocartilage Functions

Resists Compression


Absorbs Shock

Fibrocartilage Locations

- Intervertebral Discs


- Discs of Knee Joints

What is bone characterized by?

A hard, calcified extracellular matrix through which many collagen fibers run

What are the specialized cells found within bone?

Osteoblast (immature cells that secrete the extracellular matrix) and Osteocytes (mature cells that maintain the bone matrix)

2 types of bones

Compact and Spongy

What is blood?

An atypical connective tissue consisting of cells surrounded by nonliving, liquid matrix (plasma)

Blood Functions

- transport of respiratory gases, nutrients, and wastes

Blood Locations

- within blood vessels

4 types of membranes

1. Cutaneous: skin; designed to secrete sweat and oil


2. Mucosa: line hollow organs that open to the surface of the body; designed to secrete mucus


3. Serous: line closed ventral cavities; designed to secrete serous fluid


4. Synovial: line the joint cavity between adjacent bones; designed to secrete synovial fluid

What are the 2 layers of serous membrane

Parietal layer: will always line the body cavity wall


Visceral layer: will lie directly on the organ

What do these line?


1. Pleural Membranes


2. Pericardial Membranes


3. Peritoneal Membranes

1. Lungs


2. Heart


3. Organs of the abdominopelvic cavity

What is muscle tissue characterized of?

An abundance of muscle cells (muscle fibers) with an elongated shape that are specialized to contract or shorten

3 types of muscle tissue

1. skeletal muscle tissue


2. cardiac muscle tissue


3. smooth muscle tissue

Skeletal Muscle Tissue Functions

- Voluntary Movement


- Manipulation of environment


- Facial Expression



Skeletal Muscle Tissue Locations

skeletal muscles attached to bones

What is skeletal muscle tissue composed of?

Long, cylindrical muscle cells that are multinucleated and contain obvious striations (alternating pattern of light and dark staining)

Specialized Junctions

Cardiac Muscle fibers interconnect at intercalated discs (complex junctions containing desmosome-type junctions and gap junctions that allow ions to pass between cells, transmitting the contraction signal from one cell to the next)

Cardiac muscle tissue composed of?

Branching muscle cells with striations and usually one nucleus

Cardiac Muscle Tissue Function/Location

- Contracts involuntarily to propel blood


- Occurs in walls of heart

What is smooth muscle tissue composed of?

Spindle-shaped cells with one central nucleus and no striations. Arranged closely to form sheets

Smooth Muscle Tissue Functions/Location

1. propels substances along internal passageways by alternately contracting and relaxing


2. involuntary control




- mostly walls of hollow organs

Nervous tissue characterized by?

An abundance of neurons and neuroglial cells with minimal connective tissue support

Neurons

Specialized nerve cells that generate and conduct electrical impluses

Neuroglial Cells

Supporting cells that nourish, isolate and protect neurons

Nervous Tissue Functions/Location

1. Transmit electrical signals from sensory receptors


2. Integrate Information


3. Transmit Electrical Signals to Effectors




- Brain, Spinal Cord, and Nerves