Reading...
Play button
Play button
Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
23 Cards in this Set
- Front
- Back
|
6 Inner mitochondrial membrane proteins for ETC (In order of the chain)
(Embedded, inside, or outside inner membrane of mitochrondria???) |
1. NADH dehydrogenase complex (Embedded) (Complex 1)
2. ubiquinone (Inside) 3. Succinate Dehydrogenase (Outside) (Complex II - for FADH2) 4. Cytochrome b-c complex (Embedded) (Complex III) 5. Cytochrome c (outside) 6. Cytochrome Oxidase complex (Embedded) (Complex IV) |
|
|
Which of the 2 components in ETC are mobile carriers? Not complexes
|
Ubiquinone (Coenzyme Q10 (Q10 or CoQ) and Cytochrome C
|
|
|
What is special about Succinate Dehydrogenase?
|
Used in TCA cycle for FADH2 (converted back into FAD)
|
|
|
What is special about Ubiquinone?
|
Coenzyme Q10 (Q10 or CoQ)
Not protein but large complex organic lipid soluble organic mobile electron carrier |
|
|
What is special about Cytochrome C?
|
Small protein that contains Heme group.
Highly conserved |
|
|
What is involved in all 4 clusters (metal)?
|
Iron
(Iron sulphur clusters and heme groups) |
|
|
Which metal is in complex 4?
|
Copper
|
|
|
What are the 3 proton pumping sites?
|
NADH dehydrogenase (complex I)
Cytochrome bc1 complex (Complex III) Cytochrome oxidase (Complex IV) |
|
|
Rotenone, an insecticide, inhibits at ________
|
complex I
|
|
|
Antibiotic Antimycin A inhibits at complex _______
|
Complex III
|
|
|
Cyanide, Azide, CO inhibit at _______
|
complex IV
|
|
|
Ceramide inhibits _______
|
complex III
|
|
|
Methamphetamine inhibits _______
|
Complex IV
|
|
|
Barbiturates inhibit at _______
|
Complex I
|
|
|
3 ways ATP can be synthesized
|
1. Substrate level phosphorylation
2. photophosphorylation 3. Oxidative phosphorylation |
|
|
Substrate Phosphorylation?
|
Direct transfer of phosphate group from a sugar phosphate to ADP = ATP
|
|
|
Photophosphorylation?
|
ATP generated during photosynthesis in chloroplasts of plant/algae cells.
Protons go to THylakoid space and back into stroma to generate ATP |
|
|
Oxidative Phosphorylation (OxPh)
|
Prokaryotes = plasma membrane
ATP formed via ATP synthase Chemiosmosis |
|
|
Chemiosmosis? Creates what?
|
Generating ATP from proton gradient = forming Proton Motive Force
|
|
|
ATP Synthase important info
|
pumps protons from Mitochondrial Matrix into intermembrane space
Complex V of respiratory system Located on inner mitochondrial membrane Can hydrolyze ATP also |
|
|
2 components of ATP synthase
3 named parts of ATP synthase? |
F[1] and F[0]
Catalytic Head, Stalk, and Rotor |
|
|
What happens when ETC and ATP synthase are uncoupled
|
H+ does not travel back through ATP synthase (ETC continues but ATP synthase does not)
Energy released as heat - hibernation |
|
|
P/O ratio tells us?
|
tells us how many moles of ATP are made for each mole of oxygen atom used
|
