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13 Cards in this Set

  • Front
  • Back
Which protein functions to facilitate diffusion of oxygen through cells to mitochondria where it is consumed?
Myoglobin
non-polypeptide portions of proteins necessary for activity
Prosthetic Group
is a porphyrin with iron at its center
heme
The type of porphyrin found in hemoglobin and myoglobin
Protoporphyrin IX
Which state must heme iron be in to bind oxygen?
Fe2+
Structure has 153 amino acids which assumes a compact globular shape
Myoglobin
Proximal Histidine
HisF8
Distal Histidine
HisE7
Which residue in myoglobin forms a bond with heme iron
His F8, proximal histidine
Which residue in myoglobin forms a bond with oxygen?
His E7, distal histidine
indicates whether the binding of one ligand influences the binding of another
cooperativity
Hb exhibits ________ cooperativity.
Positive
Changes in residues on the _______ surface of the hemoglobin molecule rarely affect function or have pathological effects.
Outer