Biochemistry Cho, Cholesterol And Lipid Metabolism

Front 1

Pyruvate Dehydrogenase complex E1- name its major reactants, products, cofactors and regulators

Back 1

Reactant: pyruvate
Product: 2C pyruvate fragment
Cofactor: thiamine pyrophosphate (prosthetic)
Regulation: Phosphorylation (deactivated by PDH kinase/activated by PDH phophotase) Allosterically by: acetyl CoA and NADH

Front 2

Pyruvate Dehydrogenase complex E2- name its major reactants, products, cofactors and regulators

Back 2

R: 2C pyruvate fragment
P: acetyl CoA
C: CoA (co-substrate) from pantothenic acid / Lipoamide (prosthetic)
Reg: feedback inhibition by acetyl CoA product

Front 3

Pyruvate Dehydrogenase complex E3- name its major reactants, products, cofactors and regulators

Back 3

R: lipoate, FADH2, NAD+
P:oxidized lipoate on E2 and NADH
C: FAD (prosthetic) from riboflavin / NAD+ (co-substrate) from niacin
Reg:

Front 4

Citric acid Cycle enzymes that produce NADH

Back 4

Isocitrate Dehydrogenase
a-Ketoglutarate Dehydrogenase
Malate Dehydrogenase

Front 5

Citric acid cycle enzyme that produces FADH2

Back 5

Succinate Dehydrogenase

Front 6

Citric acid cycle enzyme that Produces GTP

Back 6

Succinyl CoA synthetase