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19 Cards in this Set
- Front
- Back
SOD
|
reactive O2* -> H2O2
|
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Myeloperoxidase
|
H2O2 -> HOCl*
(makes bleach to kill bac) |
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Catalase
|
H2O2 -> H2O
(neutralizes excess peroxide) |
|
NADPH oxidase
|
O2 -> O2*
(makes reactive O2 species, NADPH becomes NADP+ as a result of this enzymatic rxn) |
|
aldose reductase
|
glucose -> sorbitol
(lens, retina, schwann, seminal vesicles) **Hyperglycemia-> inc glucose in cell, add NADPH and aldose reductase makes sorbitol, which gets trapped inside, accumulates -> osmotic swelling -> cataracts, peripheral neuropathy in diabetes) |
|
Acidic amino acids
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Asp, Glu
(acidic AA are NEGATIVELY charged) |
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Basic amino acids
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Arg, Lys
(basic AA are POSITIVELY charged; this is why histones bind negatively-charged DNA so well) |
|
Which AAs have extra NH3 group?
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Arg, Lys
|
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Which AA is most basic? (=most positive)
|
Arg
|
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Which AA is involved in vasodilation?
|
Arg
(Arg + NOS -> NO) |
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Which AA has no net charge?
|
His
(a basic amino acid) |
|
Why is hyperammonemia bad?
|
alpha-ketoglutarate+NH3 <=>glutamate
excess NH3 makes more glutamate and less alpha-KG, which is needed for TCA, which the brain depends on (NH3 steals energy from the brain) |
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DNA polymerase I
|
polymerization of nucleotides; also functions in processing and repair mechanisms
|
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DNA polymerase III
|
major replicating enzyme in e.coli?
|
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chiasma
|
cross-like structure formed when 2 homologous chromosomes exchange material
|
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synapsis
|
proper name for the pairing of homolougous chromosomes with which meiosis begins
|
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Tripolar mitoses
|
abnl mitoses resulting from abnl mitotic spindles
-in tumor cells, evidence of malignancy |
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AAUAAA
|
sequence that must be recognized in order for mRNA polyadenylation to occur
|
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AAUAAA
|
sequence that must be recognized in order for mRNA polyadenylation to occur
|