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31 Cards in this Set
- Front
- Back
Why is water an excellent solvent for bio molecules?
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Most bio molecules are charged or polar.
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pH = what?
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pH = -log [H+]
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pKa = what?
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pKa = -log Ka
(Ka = [products]/[reactants]) |
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What does Ka represent?
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Ka = [products]/[reactants]
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What is specific heat?
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the heat required to raise the temperature of one gram of a substance one degree centigrade
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Which elements can H-bond?
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F, O, N, S
(F is rarely found in bio molecules) |
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Why are straight H-bonds stronger than bent ones?
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Just because...
Think of them like vectors... |
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What kind of bond holds together DNA?
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H-bonds
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What does amphipathic mean?
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Having both polar and non-polar characteristics.
amphi- both -pathy feeling (sympathy) |
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What percent of a molecule is acidic and what percent is basic at the molecule's pKa?
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Both are 50/50 percent
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Why are micelles more entropically favorable than single fatty acids in a water solution?
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More molecules together means more water molecules not in hydration shells (there are more pieces to the systems and more entropy).
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Why is CO2 not soluble in water?
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It is a linear molecule and therefore non-polar.
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What is a polymorphic protein?
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Proteins with AA variants found in different members of the same species.
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What percent of proteins are polymorphic?
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20-30%
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Which is the only AA that has no chiral center?
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Glycine
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What is the average AA mass?
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110 Daltons
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What is a Zwitter ion?
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A molecule that has both positive and negative charges and is neutral.
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What is the pI?
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The isoelectric point, or the point at which a molecule has a 0 net charge.
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What is activity of proteins vs. specific activity of proteins?
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activity = amount of a certain protein in a solution (the physical number)
specific activity = the ratio of a specific protein to the solution (a measure of purity) |
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What is a polymorphic protein?
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A protein with amino acid variants found within the same species of organism (20-30% of all proteins are polymorphic)
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What does the L stand for in an L-configuration?
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Levorotary (rotating polarized light to the left)
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What does the D stand for in an D-configuration?
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Dextrorotary (rotating polarized light ot the right)
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How can one determine if an amino acid is in an L or D configuration?
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In a fisher projection, when the carboxyl group is at the top, the H on the right and the functional group on the left, it's L. If conversely, it's D.
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Which AA is not chiral?
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glycine (two H's off normally chiral carbon)
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What is the average amino acid mass?
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110 AMU
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What are the non-polar AA's?
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M, A, L, P, G, I, V
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What are the polar AA's?
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Q, C, S, T, N
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What are the aromatic AA's?
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W, Y, F
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What are the basic AA's?
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K, H, R
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What are the acidic AA's?
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D, E
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What is the isoelectric point?
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The pH at which a molecule is electrically neutral (having a positive and a negative charge)
Abbreviated pI |