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24 Cards in this Set
- Front
- Back
Functions of proteins |
Enzyme catalysts, defense, transport, support, motion, regulation, and storage |
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Stereoisomers vs enamtiomers vs diastereomers |
S: same backbone but different orientations E: mirror images that can’t be superimposed D: two/more differences between two stereoisomers |
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D or L: sugars and amino acids |
Sugars: D AA: L In humans AA are D in bacteria |
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AA non polar and aliphatic |
Val, Leu, Ile, Gly, Ala, Pro |
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AA branched chain |
Val, Leu, and Ile Also metabolized in the liver and the skeletal muscle |
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AA sulphur containing |
Cys (polar) and Met (non polar) |
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AA aromatic |
Phe (non polar), Tyr (polar), and Trp (non polar) Also absorbs UV light At 280 nm |
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Phenylalanine facts you should know |
Essential and forms tyrosine |
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Tyrosine facts |
Precursor of melanin and is used for O-linked glycosylation Catecholamines: dopamine, norepinephrine, and epinephrine act as neurotransmitters Parkinson’s is a deficiency of dopamine Synthesis of thryoxine |
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Tryptophan facts |
Important for melatonin(circadian rhythm), serotonin(mood alterations), and source of niacin(deficiency causes hartnup disease) |
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AA with OH groups |
Ser, Thr, and Tyr these are all polar Used as targets for phosphorylation |
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AA acidic groups (polar) |
Asp, Asn, Glu, Gln |
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Asparagine (Asn) is used for what |
N-linked glycosylation |
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Chinese restaurant syndrome |
Caused by MSG and symptoms due to excitogenic effects on Glutamate. Will be flushed and tired |
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AA with basic groups (polar) |
Arg, Lys, and His(sometimes) |
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Arginine will be seen where |
In synthesis of NO (which cause vasodilation), release of urea |
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Histidine |
Neutral at physiological pH but can be positive or neutral depending on environment Important buffer in plamsa |
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Essential AA |
PVT TIM HALL Phenylalanine, Valine, Tryptophan Threonine, Isoleucine, Methionine Histidine, Arginine, Leucine, lysine |
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Semi essential AA |
Cys from Met Tyr from Phe |
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Glucogenic, ketogenic, both? |
Most are Gluco- Keto- Leu and Lys Both: Tyr, Ile, Phe, and Trp |
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pKa which have two or three values |
AA with ionizable groups have 3 AA w/ Out ionizable groups have 2 |
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Isoelectric focusing technique |
Use pI to separate proteins |
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Maple syrup disease |
Defect in breaking down of Val, Leu, and/or Ile Sweet pee |
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AA with three pKa curves |
His, Arg, Lys, Asp, Glu, Cys, and Tyr |