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15 Cards in this Set
- Front
- Back
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Who was the first to describe DNA structure and propose a mechanism for DNA replication? What year was this acomplished?
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In 1953 WATSON AND CRICK described DNA structure and proposed a mechanism for DNA replication.
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All of the Following are Pyrimidines except?
a) Uracil b) Thymine c) Guanine d) Cytosine |
Guanine is a purine and not a pyrimidine
Remember CUT Py! |
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Who established that the DNA of closely related species had similar base composition?
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Erwin Chargaff in 1940
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What 3 things make up DNA?
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Base: Purine (A or T) or Pyrimidine (C or U)
Sugar: 2 deoxyribose Phosphate: Inorganic Phosphate |
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The human genome contains how many nucleotides?
a) 300 b) 3000 c) 3 Trillion d) 3 Million e) 3 billion f) Way to many to count |
The human genome contains approx. 3 BILLION nucleotides
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True or False?
DNA bio synthesis occurs in a 3'----5' Direction ? |
FALSE!!!!
DNA replicates in the 5'-----3' direction. |
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True or False
The secondary Structure of DNA is rigid and can bend |
TRUE
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Why is that the regions of the DNA that are high in A-T are the FIRST to denature during DNA replication and Transcription?
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The A-T Bond is easily denatured do to only having 2 hydrogen bonds!
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Which Form is the most common form of DNA?
A: a form B: b form C: c Form D: d form |
The B from is the most common form of DNA
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Histones are basic proteins with an abundance of ________ & _______ residues that readily form ionic links with the DNA ?
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Histones are basic proteins with an abundance of ARGININE & LYSINE residues that readily form ionic links with the DNA
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True or False
In Eukaryotes, the DNA polymerase alpha primase complex is the ONLY enzyme that exhbits primase activity |
TRUE
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Who coined the term "Polymerase"
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Aurthur Kornberg
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What two things the DNA-Dependent DNA polymerase require in order to synthezise a new strand of DNA?
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1) Template
2) Primer |
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What enzyme is responsible for proof reading the New DNA Strand?
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Exonuclease is responsible for Proof reading of the new DNA sequence.
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True or False
DNA polymerase 1 posesses only a 5'----3' EXONUCLEASE enzyme? |
FALSE, the unique thing about DNA polymerase 1 is that it has both a 5'------3' and a 3'-------5' Exonuclease.
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